Search Results - "Hogg, K. J."

Heterocellular OSM-OSMR signalling reprograms fibroblasts to promote pancreatic cancer growth and metastasis by Lee, Brian Y., Hogg, Elizabeth K. J., Below, Christopher R., Kononov, Alexander, Blanco-Gomez, Adrian, Heider, Felix, Xu, Jingshu, Hutton, Colin, Zhang, Xiaohong, Scheidt, Tamara, Beattie, Kenneth, Lamarca, Angela, McNamara, Mairéad, Valle, Juan W., Jørgensen, Claus

“…Pancreatic ductal adenocarcinoma (PDA) is a lethal malignancy with a complex microenvironment. Dichotomous tumour-promoting and -restrictive roles have been…”
Get full text

A CDK1 phosphorylation site on Drosophila PAR-3 regulates neuroblast polarisation and sensory organ formation by Loyer, Nicolas, Hogg, Elizabeth K J, Shaw, Hayley G, Pasztor, Anna, Murray, David H, Findlay, Greg M, Januschke, Jens

“…The generation of distinct cell fates during development depends on asymmetric cell division of progenitor cells. In the central and peripheral nervous system…”
Get full text

Proteomic and functional comparison between human induced and embryonic stem cells by Brenes, Alejandro J, Griesser, Eva, Sinclair, Linda V, Davidson, Lindsay, Prescott, Alan R, Singh, Francois, Hogg, Elizabeth KJ, Espejo-Serrano, Carmen, Jiang, Hao, Yoshikawa, Harunori, Platani, Melpomeni, Swedlow, Jason R, Findlay, Greg M, Cantrell, Doreen A, Lamond, Angus I

“…Human induced pluripotent stem cells (hiPSCs) have great potential to be used as alternatives to embryonic stem cells (hESCs) in regenerative medicine and…”
Get full text

Limited clinical utility of CT coronary angiography in a district hospital setting by JENKINS, S. M. M, JOHNSTON, N, DUNN, F. G, HAWKINS, N. M, MESSOW, C.-M, SHAND, J, HOGG, K. J, ETEIBA, H, MCKILLOP, G, GOODFIELD, N. E. R, MCCONNACHIE, A

“…Studies have demonstrated considerable accuracy of multi-slice CT coronary angiography (MSCT-CA) in comparison to invasive coronary angiography (I-CA) for…”
Get full text

Resolution of dynamic left ventricular outflow tract obstruction caused by retained native leaflets following mitral valve replacement using medical treatment by Watt, J, Hogg, K J, Danton, M

“…Peak LVOT gradient was 120 mm Hg and the patient remained breathless on minimal exertion. Because the patient was frail she was managed medically by cessation…”
Get full text

Effect of subcutaneous sumatriptan, a selective 5HT1 agonist, on the systemic, pulmonary, and coronary circulation by MACINTYRE, P. D, BHARGAVA, B, HOGG, K. J, GEMMILL, J. D, HILLIS, W. S

“…Sumatriptan (GR43175) is a selective 5-hydroxytryptamine (5HT1) receptor agonist effective in the acute treatment of migraine. Recent in vitro experiments…”
Get full text

Comparison of survival following coronary artery bypass grafting vs. percutaneous coronary intervention in diabetic and non-diabetic patients: retrospective cohort study of 6320 procedures by Pell, J. P., Pell, A. C. H., Jeffrey, R. R., Jennings, K., Oldroyd, K., Eteiba, H., Hogg, K. J., Murday, A., Faichney, A., Colquhoun, I., Berg, G., Starkey, I. R., Flapan, A., Mankad, P.

“…Aim  To determine whether mortality following percutaneous coronary intervention vs. coronary bypass grafting varies according to whether or not patients have…”
Get full text

Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity by Hutton, Colin, Heider, Felix, Blanco-Gomez, Adrian, Banyard, Antonia, Kononov, Alexander, Zhang, Xiaohong, Karim, Saadia, Paulus-Hock, Viola, Watt, Dale, Steele, Nina, Kemp, Samantha, Hogg, Elizabeth K.J., Kelly, Joanna, Jackstadt, Rene-Filip, Lopes, Filipa, Menotti, Matteo, Chisholm, Luke, Lamarca, Angela, Valle, Juan, Sansom, Owen J., Springer, Caroline, Malliri, Angeliki, Marais, Richard, Pasca di Magliano, Marina, Zelenay, Santiago, Morton, Jennifer P., Jørgensen, Claus

“…Fibroblasts display extensive transcriptional heterogeneity, yet functional annotation and characterization of their heterocellular relationships remains…”
Get full text

Functions of SRPK, CLK and DYRK kinases in stem cells, development, and human developmental disorders by Hogg, Elizabeth K J, Findlay, Greg M

“…Human developmental disorders encompass a wide range of debilitating physical conditions and intellectual disabilities. Perturbation of protein kinase…”
Get full text

Outcomes following coronary artery bypass grafting and percutaneous transluminal coronary angioplasty in the stent era: a prospective study of all 9890 consecutive patients operated on in Scotland over a two year period by Pell, J P, Walsh, D, Norrie, J, Berg, G, Colquhoun, A D, Davidson, K, Eteiba, H, Faichney, A, Flapan, A, Hogg, K J, Jeffrey, R R, Jennings, K, McArthur, J, Mankad, P, Oldroyd, K, Pell, A C H, Starkey, I R

“…OBJECTIVE To determine current outcomes of percutaneous transluminal coronary angioplasty (PTCA) and coronary artery bypass grafting (CABG). DESIGN The…”
Get full text

How should we optimize cardiac resynchronization therapy? by Stanton, Tony, Hawkins, Nathaniel M., Hogg, Kerry J., Goodfield, Nicholas E.R., Petrie, Mark C., McMurray, John J.V.

“…Optimization of cardiac resynchronization therapy is increasingly performed. Numerous methods have been proposed, many being echocardiographic. Both the…”
Get full text

Direct admission to the coronary care unit by the ambulance service for patients with suspected myocardial infarction by Prasad, N, Wright, A, Hogg, K J, Dunn, F G

“…Background Direct access to the coronary care unit (CCU) for general practitioner (GP) referred cases of suspected acute myocardial infarction (AMI) (fast…”
Get full text

Use of fax facility improves decision making regarding thrombolysis in acute myocardial infarction by Srikanthan, V. S., Pell, A. C., Prasad, N., Tait, G. W., Rae, A. P., Hogg, K. J., Dunn, F. G.

“…BACKGROUND: Electrocardiography is the fundamental investigation for decision making regarding thrombolytic treatment in acute myocardial infarction (MI)…”
Get full text

Pre-dosing antibody levels and efficacy of thrombolytic drugs containing streptokinase by Gemmill, J D, Hogg, K J, Dunn, F G, Rae, A P, Hillis, W S

“…OBJECTIVE--To evaluate the influence of pretreatment streptokinase resistance titre and the concentration of IgG antibodies to streptokinase on the efficacy of…”
Get full text

Balsalazide-induced myocarditis by Robertson, E, Austin, D, Jamieson, N, Hogg, K.J

“…Abstract A 38 year-old man with ulcerative colitis recently treated with balsalazide was admitted with chest pain. Investigations demonstrated myocardial…”
Get full text

Angiographic patency study of anistreplase versus streptokinase in acute myocardial infarction by Hogg, K J, Gemmill, J D, Burns, J M, Lifson, W K, Rae, A P, Dunn, F G, Hillis, W S

“…128 patients with acute myocardial infarction of duration 6 h or less were randomised in double-blind fashion to receive 30 U anistreplase over 5 min or 1.5 MU…”
Get more information

A pilot study of the efficacy and safety of bolus administration of alteplase in acute myocardial infarction by Gemmill, J D, Hogg, K J, MacIntyre, P D, Booth, N, Rae, A P, Dunn, F G, Hillis, W S

“…OBJECTIVE--To examine the efficacy, safety, and the pharmacokinetic profile of a bolus dose administration regimen of alteplase in the treatment of acute…”
Get full text

Electrocardiographic prediction of coronary artery patency after thrombolytic treatment in acute myocardial infarction: use of the ST segment as a non-invasive marker by Hogg, K J, Hornung, R S, Howie, C A, Hockings, N, Dunn, F G, Hillis, W S

“…The predictive value of the measurement of changes in ST segment elevation was assessed as a non-invasive marker of coronary artery reperfusion after…”
Get full text

Rapid access chest pain clinics--can they be justified? by McGavigan, A D, Begley, P E, Moncrieff, J, Hogg, K J, Dunn, F G

“…Rapid access chest pain clinics are expanding across the country with marked resource implications despite a paucity of data regarding their efficacy. Early…”
Get more information

The incidence and mechanism of hypotension following thrombolytic therapy for acute myocardial infarction with streptokinase-containing agents--lack of relationship to pretreatment streptokinase resistance by Gemmill, J D, Hogg, K J, Douglas, J T, Dunn, F G, Lowe, G D, Rae, A P, Hillis, W S

“…The incidence, amplitude, mechanism and relationship to prior exposure to streptococcal antigen of blood pressure changes to streptokinase-containing…”
Get more information