Search Results - "Hogg, JC"
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Pathophysiology of airflow limitation in chronic obstructive pulmonary disease
Published in The Lancet (British edition) (21-08-2004)“…The airflow limitation that defines chronic obstructive pulmonary disease (COPD) is the result of a prolonged time constant for lung emptying, caused by…”
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2
The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease
Published in The New England journal of medicine (24-06-2004)“…Physiological observations indicate that the small airways are the predominant site of airway obstruction in patients with chronic obstructive pulmonary…”
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3
Decreased Histone Deacetylase Activity in Chronic Obstructive Pulmonary Disease
Published in The New England journal of medicine (12-05-2005)“…The balance between histone deacetylase activity and histone acetyltransferase activity is one of the mechanisms controlling and limiting inflammatory cell…”
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4
Bacterial microbiome of lungs in COPD
Published in International journal of chronic obstructive pulmonary disease (01-01-2014)“…Chronic obstructive pulmonary disease (COPD) is currently the third leading cause of death in the world. Although smoking is the main risk factor for this…”
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5
The Prediction of Small Airway Dimensions Using Computed Tomography
Published in American journal of respiratory and critical care medicine (15-01-2005)“…Chronic obstructive pulmonary disease is characterized by destruction of the lung parenchyma and/or small airway narrowing. To determine whether the dimensions…”
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Why does airway inflammation persist after the smoking stops?
Published in Thorax (01-02-2006)“…A cross sectional study of small airway pathology across the GOLD categories of COPD has shown that the decline in FEV1 is more closely associated with a…”
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7
Particulate air pollution induces progression of atherosclerosis
Published in Journal of the American College of Cardiology (20-03-2002)“…We sought to determine the effect of exposure to air pollution particulate matter <10 μm (PM10) on the progression of atherosclerosis in rabbits. Epidemiologic…”
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The Prevalence of Chronic Obstructive Pulmonary Disease (COPD) and the Heterogeneity of Risk Factors in the Canadian Population: Results from the Canadian Obstructive Lung Disease (COLD) Study
Published in International journal of chronic obstructive pulmonary disease (01-01-2021)“…To determine the spirometric-based prevalence of COPD across different regions in Canada and to evaluate the site heterogeneity of risk factors. In this…”
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9
Convergence of the epidemiology and pathology of COPD
Published in Thorax (01-01-2006)“…The epidemiology of chronic obstructive pulmonary disease (COPD) has been dominated by one hypothesis stating that cigarette smoking and chronic bronchitis…”
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Cytokines Involved in the Systemic Inflammatory Response Induced by Exposure to Particulate Matter Air Pollutants (PM10)
Published in American journal of respiratory and critical care medicine (01-09-2001)“…Elevated levels of ambient particulate matter (PM(10)) have been associated with increased cardiopulmonary morbidity and mortality. We previously showed that…”
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11
Comprehensive Gene Expression Profiles Reveal Pathways Related to the Pathogenesis of Chronic Obstructive Pulmonary Disease
Published in Proceedings of the National Academy of Sciences - PNAS (12-10-2004)“…To better understand the molecular basis of chronic obstructive pulmonary disease (COPD), we used serial analysis of gene expression (SAGE) and microarray…”
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12
Association of Chronic Obstructive Pulmonary Disease Severity and Pneumocystis Colonization
Published in American journal of respiratory and critical care medicine (15-08-2004)“…Factors modulating the variable progression of chronic obstructive pulmonary disease (COPD) are largely unknown, but infectious agents may play a role. Because…”
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13
Characterization of airway plugging in fatal asthma
Published in The American journal of medicine (01-07-2003)“…Case reports suggest that deaths due to asthma can occur without airway plugging. In this study, we examined the hypothesis that obstruction of the airway…”
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14
Role of latent viral infections in chronic obstructive pulmonary disease and asthma
Published in American journal of respiratory and critical care medicine (15-11-2001)“…Acute viral respiratory tract infections are well known to precipitate asthma attacks and acute exacerbations of chronic obstructive pulmonary disease, but…”
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15
Radiologic findings are strongly associated with a pathologic diagnosis of usual interstitial pneumonia
Published in Chest (01-10-2003)“…To determine which clinical and radiologic findings are independently associated with a pathologic diagnosis of usual interstitial pneumonia (UIP). We recently…”
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16
Computed tomographic measurements of airway dimensions and emphysema in smokers: Correlation with lung function
Published in American journal of respiratory and critical care medicine (01-09-2000)“…Chronic obstructive pulmonary disease (COPD) is characterized by the presence of airflow obstruction caused by emphysema or airway narrowing, or both. Low…”
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17
Amplification of Inflammation in Emphysema and Its Association with Latent Adenoviral Infection
Published in American journal of respiratory and critical care medicine (01-08-2001)“…This study examines the hypothesis that the cigarette smoke-induced inflammatory process is amplified in severe emphysema and explores the association of this…”
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18
Reduction in airway hyperresponsiveness to methacholine by the application of RF energy in dogs
Published in Journal of applied physiology (1985) (01-11-2004)“…1 Asthmatx, 5 Broncus Technologies, Mountain View 94043; 2 Department of Pathology, Stanford University-El Camino Hospital, Mountain View 94040; 3 Department…”
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Particulate Matter Induces Cytokine Expression in Human Bronchial Epithelial Cells
Published in American journal of respiratory cell and molecular biology (01-09-2001)“…The present study was designed to determine cytokines produced by primary human bronchial epithelial cells (HBECs) exposed to ambient air pollution particles…”
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Interaction of Alveolar Macrophages and Airway Epithelial Cells Following Exposure to Particulate Matter Produces Mediators that Stimulate the Bone Marrow
Published in American journal of respiratory cell and molecular biology (01-07-2002)“…Exposure to ambient air pollution particles with a diameter of < 10 microm (PM(10)) has been associated with increased cardiopulmonary morbidity and mortality…”
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