Search Results - "Hogervorst, F."

Triple-negative breast cancer: BRCAness and concordance of clinical features with BRCA1-mutation carriers by Lips, E H, Mulder, L, Oonk, A, van der Kolk, L E, Hogervorst, F B L, Imholz, A L T, Wesseling, J, Rodenhuis, S, Nederlof, P M

“…Background: BRCAness is defined as shared tumour characteristics between sporadic and BRCA-mutated cancers. However, how to exactly measure BRCAness and its…”
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Cancer risks in BRCA2 families: estimates for sites other than breast and ovary by van Asperen, C J, Brohet, R M, Meijers-Heijboer, E J, Hoogerbrugge, N, Verhoef, S, Vasen, H F A, Ausems, M G E M, Menko, F H, Gomez Garcia, E B, Klijn, J G M, Hogervorst, F B L, van Houwelingen, J C, van’t Veer, L J, Rookus, M A, van Leeuwen, F E

“…Background: In BRCA2 mutation carriers, increased risks have been reported for several cancer sites besides breast and ovary. As most of the families included…”
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Clinical spectrum of ataxia-telangiectasia in adulthood by VERHAGEN, M. M. M, ABDO, W. F, BROEKS, A, LAST, J. I, VAN'T VEER, L. J, TIJSSEN, M. A. J, DUBOIS, A. M. I, KREMER, H. P. H, WEEMAES, C. M. R, TAYLOR, A. M. R, VAN DEUREN, M, WILLEMSEN, M. A. A. P, HOGERVORST, F. B. L, SMEETS, D. F. C. M, HIEL, J. A. P, BRUNT, E. R, VAN RIJN, M. A, KRAKAUER, D. Majoor, OLDENBURG, R. A

“…To describe the phenotype of adult patients with variant and classic ataxia-telangiectasia (A-T), to raise the degree of clinical suspicion for the diagnosis…”
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A multiplex PCR predictor for aCGH success of FFPE samples by VAN BEERS, E. H, JOOSSE, S. A, LIGTENBERG, M. J, FLES, R, HOGERVORST, F. B. L, VERHOEF, S, NEDERLOF, P. M

“…Formalin-fixed, paraffin-embedded (FFPE) tissue archives are the largest and longest time-spanning collections of patient material in pathology archives…”
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The carcinogenicity of dietary acrylamide intake: A comparative discussion of epidemiological and experimental animal research by Hogervorst, Janneke G. F., Baars, Bert-Jan, Schouten, Leo J., Konings, Erik J. M., Goldbohm, R. Alexandra, van den Brandt, Piet A.

“…Since 2002, it is known that the probable human carcinogen acrylamide is present in commonly consumed carbohydrate-rich foods, such as French fries and potato…”
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Impact of rapid genetic counselling and testing on the decision to undergo immediate or delayed prophylactic mastectomy in newly diagnosed breast cancer patients: findings from a randomised controlled trial by Wevers, M R, Aaronson, N K, Verhoef, S, Bleiker, E M A, Hahn, D E E, Kuenen, M A, van der Sanden-Melis, J, Brouwer, T, Hogervorst, F B L, van der Luijt, R B, Valdimarsdottir, H B, van Dalen, T, Theunissen, E B M, van Ooijen, B, de Roos, M A, Borgstein, P J, Vrouenraets, B C, Vriens, E, Bouma, W H, Rijna, H, Vente, J P, Witkamp, A J, Rutgers, E J T, Ausems, M G E M

“…Background: Female breast cancer patients with a BRCA1/2 mutation have an increased risk of contralateral breast cancer. We investigated the effect of rapid…”
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Ataxia–telangiectasia patients presenting with hyper-IgM syndrome by Noordzij, J G, Wulffraat, N M, Haraldsson, Á, Meyts, I, Veer, L J van’t, Hogervorst, F B L, Warris, A, Weemaes, C M R

“…Ataxia–telangiectasia (A–T) is characterised by progressive neurological abnormalities, oculocutaneous telangiectasias and immunodeficiency (decreased serum…”
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Dietary acrylamide intake and the risk of lymphatic malignancies: the Netherlands Cohort Study on diet and cancer by Bongers, Mathilda L, Hogervorst, Janneke G F, Schouten, Leo J, Goldbohm, R Alexandra, Schouten, Harry C, van den Brandt, Piet A

“…Acrylamide, a probable human carcinogen, is present in many everyday foods. Since the finding of its presence in foods in 2002, epidemiological studies have…”
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Interaction between dietary acrylamide intake and genetic variants for estrogen receptor-positive breast cancer risk by Hogervorst, Janneke G. F., van den Brandt, Piet A., Godschalk, Roger W. L., van Schooten, Frederik-Jan, Schouten, Leo J.

“…Purpose The association between dietary acrylamide intake and estrogen receptor-positive (ER+) breast cancer risk in epidemiological studies is inconsistent…”
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A non-BRCA1/2 hereditary breast cancer sub-group defined by aCGH profiling of genetically related patients by Didraga, M. A., van Beers, E. H., Joosse, S. A., Brandwijk, K. I. M., Oldenburg, R. A., Wessels, L. F. A., Hogervorst, F. B. L., Ligtenberg, M. J., Hoogerbrugge, N., Verhoef, S., Devilee, P., Nederlof, P. M.

“…Germline mutations in BRCA1 and BRCA2 explain approximately 25% of all familial breast cancers. Despite intense efforts to find additional high-risk breast…”
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TP53 germline mutation testing in early-onset breast cancer: findings from a nationwide cohort by Bakhuizen, J. J., Hogervorst, F. B., Velthuizen, M. E., Ruijs, M. W., van Engelen, K., van Os, T. A., Gille, J. J., Collée, M., van den Ouweland, A. M., van Asperen, C. J., Kets, C. M., Mensenkamp, A. R., Leter, E. M., Blok, M. J., de Jong, M. M., Ausems, M. G.

“…Early-onset breast cancer may be due to Li–Fraumeni Syndrome (LFS). Current national and international guidelines recommend that TP53 genetic testing should be…”
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Potential role of gene-environment interactions in ion transport mechanisms in the etiology of renal cell cancer by Deckers, Ivette A. G., van den Brandt, Piet A., van Engeland, Manon, van Schooten, Frederik J., Godschalk, Roger W. L., Keszei, András P., Hogervorst, Janneke G. F., Schouten, Leo J.

“…We investigated the ion transport mechanism (ITM) in renal cell cancer (RCC) etiology using gene-environment interactions between candidate single nucleotide…”
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Bias Explains Most of the Parent-of-Origin Effect on Breast Cancer Risk in BRCA1/2 Mutation Carriers by Vos, Janet R, Oosterwijk, Jan C, Aalfs, Cora M, Rookus, Matti A, Adank, Muriel A, van der Hout, Annemarie H, van Asperen, Christi J, Gómez Garcia, Encarna B, Mensenkamp, Arjen R, Jager, Agnes, Ausems, Margreet G E M, Mourits, Marian J, de Bock, Geertruida H

“…Paternal transmission of a BRCA mutation has been reported to increase the risk of breast cancer in offspring more than when the mutation is maternally…”
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Lung Cancer Risk in Relation to Dietary Acrylamide Intake by Hogervorst, Janneke G. F., Schouten, Leo J., Konings, Erik J. M., Goldbohm, R. Alexandra, van den Brandt, Piet A.

“…Background Acrylamide is a probable human carcinogen that is present in several heat-treated foods. In epidemiological studies, positive associations between…”
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Genomic deletions of MSH2 and MLH1 in colorectal cancer families detected by a novel mutation detection approach by GILLE, J. J. P, HOGERVORST, F. B. L, MCELGUNN, C. J, SCHOUTEN, J. P, MENKO, F. H, PALS, G, WIJNEN, J. Th, VAN SCHOOTEN, R. J, DOMMERING, C. J, MEIJER, G. A, CRAANEN, M. E, NEDERLOF, P. M, DE JONG, D

“…Hereditary non-polyposis colorectal cancer is an autosomal dominant condition due to germline mutations in DNA-mismatch-repair genes, in particular MLH1, MSH2…”
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Dietary Acrylamide Intake and the Risk of Head-Neck and Thyroid Cancers: Results From the Netherlands Cohort Study by Schouten, Leo J., Hogervorst, Janneke G. F., Konings, Erik J. M., Goldbohm, R. Alexandra, van den Brandt, Piet A.

“…Acrylamide exposure has been related to an increased incidence of oral and thyroid tumors in animal studies. In 1986, 120,852 persons (aged 55–69 years) were…”
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Dietary acrylamide and human cancer; even after 20 years of research an open question by Hogervorst, Janneke GF, Schouten, Leo J

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A field experiment with variable-suction multi-compartment samplers to measure the spatio-temporal distribution of solute leaching in an agricultural soil by Bloem, E., Hogervorst, F.A.N., de Rooij, G.H.

“…Solutes spread out in time and space as they move downwards from the soil surface with infiltrating water. Solute monitoring in the field is often limited to…”
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Validation of a database on acrylamide for use in epidemiological studies by Konings, E.J.M, Hogervorst, J.G.F, Rooij, L. van, Schouten, L.J, Sizoo, E.A, Egmond, H.P. van, Goldbohm, R.A, Brandt, P.A. van den

“…Background/Objectives: Acrylamide, a probable human carcinogen, was detected in various heat-treated foods such as French fries and potato crisps. Recently,…”
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Vegetation and soil biota response to experimentally-changed nitrogen inputs in coniferous forest ecosystems of the NITREX project by Boxman, Andries W., Blanck, Kai, Brandrud, Tor-Erik, Emmett, Bridget A., Gundersen, Per, Hogervorst, Rene F., Kjønaas, O.Janne, Persson, Hans, Timmermann, Volkmar

“…Enhancement of the atmospheric N deposition is a serious threat for the structure and function of ecosystems. Here we evaluate the ecological effects of excess…”
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