Search Results - "Hogenesch, Harm"

Mechanism of immunopotentiation and safety of aluminum adjuvants by Hogenesch, Harm

“…Aluminum-containing adjuvants are widely used in preventive vaccines against infectious diseases and in preparations for allergy immunotherapy. The mechanism…”
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Optimizing the utilization of aluminum adjuvants in vaccines: you might just get what you want by HogenEsch, Harm, O’Hagan, Derek T., Fox, Christopher B.

“…Aluminum-containing adjuvants have been used for over 90 years to enhance the immune response to vaccines. Recent work has significantly advanced our…”
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Intestinal colonization with Candida auris and mucosal immune response in mice treated with cefoperazone oral antibiotic by Das, Diprasom, HogenEsch, Harm, Thangamani, Shankar

“…, an emerging multi-drug resistant fungal pathogen, causes invasive infections in humans. The factors regulating the colonization of in host niches are not…”
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Kinetics of the inflammatory response following intramuscular injection of aluminum adjuvant by Lu, Fangjia, HogenEsch, Harm

“…Highlights • The inflammation after intramuscular injection of aluminum adjuvant was examined. • Early infiltration by neutrophils, followed by macrophages,…”
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Mechanisms of stimulation of the immune response by aluminum adjuvants by HogenEsch, Harm

“…Aluminum adjuvants are widely used in human and veterinary vaccines. They are appropriate adjuvants for vaccines that confer protection by inducing antibodies…”
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Challenges in pre-clinical testing of anti-cancer drugs in cell culture and in animal models by HogenEsch, Harm, Nikitin, Alexander Yu

“…Experiments with cultures of human tumor cell lines, xenografts of human tumors into immunodeficient mice, and mouse models of human cancer are important tools…”
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Mucosal Immunity and Protective Efficacy of Intranasal Inactivated Influenza Vaccine Is Improved by Chitosan Nanoparticle Delivery in Pigs by Dhakal, Santosh, Renu, Sankar, Ghimire, Shristi, Shaan Lakshmanappa, Yashavanth, Hogshead, Bradley T, Feliciano-Ruiz, Ninoshkaly, Lu, Fangjia, HogenEsch, Harm, Krakowka, Steven, Lee, Chang Won, Renukaradhya, Gourapura J

“…Annually, swine influenza A virus (SwIAV) causes severe economic loss to swine industry. Currently used inactivated SwIAV vaccines administered by…”
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Aluminum Adjuvants-'Back to the Future' by Laera, Donatello, HogenEsch, Harm, O'Hagan, Derek T

“…Aluminum-based adjuvants will continue to be a key component of currently approved and next generation vaccines, including important combination vaccines. The…”
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Relationship between physical and chemical properties of aluminum-containing adjuvants and immunopotentiation by Hem, Stanley L, Hogenesch, Harm

“…Aluminum-containing adjuvants are an important component of many vaccines because they safely potentiate the immune response. The structure and properties of…”
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Mechanism of activation of porcine dendritic cells by an α-D-glucan nanoparticle adjuvant and a nanoparticle/poly(I:C) combination adjuvant by Hernandez-Franco, Juan F., Xie, Shaojun, Thimmapuram, Jyothi, Ragland, Darryl, HogenEsch, Harm

“…Recent studies have shown that corn-derived cationic α-D-glucan nanoparticles, known as Nano-11, significantly increase the immune response when used as a…”
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Effect of medium-chain fatty acids on growth, health, and immune response of dairy calves by Klopp, Rebecca N., Hernandez Franco, Juan F., Hogenesch, Harm, Dennis, Tana S., Cowles, Kate E., Boerman, Jacquelyn P.

“…It is necessary for the dairy industry to reduce calf morbidity and mortality, and the reliance on antibiotics to treat sick calves, to address the growing…”
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Profiling of epidermal lipids in a mouse model of dermatitis: Identification of potential biomarkers by Franco, Jackeline, Ferreira, Christina, Paschoal Sobreira, Tiago J, Sundberg, John P, HogenEsch, Harm

“…Lipids are important structural and functional components of the skin. Alterations in the lipid composition of the epidermis are associated with inflammation…”
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Alpha-D-glucan-based vaccine adjuvants: Current status and future perspectives by Patil, Veerupaxagouda, Hernandez-Franco, Juan F., HogenEsch, Harm, Renukaradhya, Gourapura J.

“…Nanoparticles (NPs) are increasingly used as efficient vaccine antigen-delivery platforms and vaccine adjuvants. Alpha (α)-D-glucans are polysaccharide…”
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Local and Systemic Changes in Lipid Profile as Potential Biomarkers for Canine Atopic Dermatitis by Franco, Jackeline, Rajwa, Bartek, Gomes, Paulo, HogenEsch, Harm

“…Lipids play a critical role in the skin as components of the epidermal barrier and as signaling and antimicrobial molecules. Atopic dermatitis in dogs is…”
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Retinoic acid determines the precise tissue tropism of inflammatory Th17 cells in the intestine by Wang, Chuanwu, Kang, Seung G, HogenEsch, Harm, Love, Paul E, Kim, Chang H

“…Th17 cells are major effector T cells in the intestine, but the regulation of their tissue tropism within the gut is poorly understood. We investigated the…”
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Keratinocyte-specific deletion of SHARPIN induces atopic dermatitis-like inflammation in mice by Sundberg, John P, Pratt, C Herbert, Goodwin, Leslie P, Silva, Kathleen A, Kennedy, Victoria E, Potter, Christopher S, Dunham, Anisa, Sundberg, Beth A, HogenEsch, Harm

“…Spontaneous mutations in the SHANK-associated RH domain interacting protein (Sharpin) resulted in a severe autoinflammatory type of chronic proliferative…”
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SHARPIN is a key regulator of immune and inflammatory responses by Wang, Zhe, Potter, Christopher S., Sundberg, John P., Hogenesch, Harm

“…Mice with spontaneous mutations in the Sharpin gene develop chronic proliferative dermatitis that is characterized by eosinophilic inflammation of the skin and…”
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Intranasal Delivery of Inactivated Influenza Virus and Poly(I:C) Adsorbed Corn-Based Nanoparticle Vaccine Elicited Robust Antigen-Specific Cell-Mediated Immune Responses in Maternal Antibody Positive Nursery Pigs by Patil, Veerupaxagouda, Renu, Sankar, Feliciano-Ruiz, Ninoshkaly, Han, Yi, Ramesh, Anikethana, Schrock, Jennifer, Dhakal, Santosh, HogenEsch, Harm, Renukaradhya, Gourapura J

“…We designed the killed swine influenza A virus (SwIAV) H1N2 antigen (KAg) with polyriboinosinic:polyribocytidylic acid [(Poly(I:C)] adsorbed corn-derived…”
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Development of a recombinant fusion protein vaccine formulation to protect against Streptococcus pyogenes by Morefield, Garry, Touhey, Graham, Lu, Fangjia, Dunham, Anisa, HogenEsch, Harm

“…Highlights • We developed a vaccine targeting Group A Strep. • A stabilized formulation of recombinant fusion protein SpeAB was determined. • Interactions…”
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Chronic proliferative dermatitis in Sharpin null mice: development of an autoinflammatory disease in the absence of B and T lymphocytes and IL4/IL13 signaling by Potter, Christopher S, Wang, Zhe, Silva, Kathleen A, Kennedy, Victoria E, Stearns, Timothy M, Burzenski, Lisa, Shultz, Leonard D, Hogenesch, Harm, Sundberg, John P

“…SHARPIN is a key regulator of NFKB and integrin signaling. Mice lacking Sharpin develop a phenotype known as chronic proliferative dermatitis (CPDM), typified…”
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