Search Results - "Hogan, Vanessa E"

OPA1 Deficiency Associated with Increased Autophagy in Retinal Ganglion Cells in a Murine Model of Dominant Optic Atrophy by White, Kathryn E, Davies, Vanessa J, Hogan, Vanessa E, Piechota, Malgorzata J, Nichols, Philip P, Turnbull, Douglas M, Votruba, Marcela

“…To examine retinal ganglion cell (RGC) and axonal abnormalities in an ENU-induced mutant mouse carrying a protein-truncating nonsense mutation in OPA1…”
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The p.M292T NDUFS2 mutation causes complex I-deficient Leigh syndrome in multiple families by Tuppen, Helen A. L., Hogan, Vanessa E., He, Langping, Blakely, Emma L., Worgan, Lisa, Al-Dosary, Mazhor, Saretzki, Gabriele, Alston, Charlotte L., Morris, Andrew A., Clarke, Michael, Jones, Simon, Devlin, Anita M., Mansour, Sahar, Chrzanowska-Lightowlers, Zofia M. A., Thorburn, David R., McFarland, Robert, Taylor, Robert W.

“…Isolated complex I deficiency is the most frequently observed oxidative phosphorylation defect in children with mitochondrial disease, leading to a diverse…”
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Induction of long-term B-cell depletion in refractory rheumatoid arthritis patients preferentially affects autoreactive more than protective humoral immunity by Teng, Y K Onno, Wheater, Gillian, Hogan, Vanessa E, Stocks, Philip, Levarht, E W Nivine, Huizinga, Tom W J, Toes, Rene E M, van Laar, Jacob M

“…B-cell depletion has become a common treatment strategy in anti-TNF-refractory rheumatoid arthritis (RA). Although the exact mechanism of how B-cell depletion…”
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Pretreatment synovial transcriptional profile is associated with early and late clinical response in rheumatoid arthritis patients treated with rituximab by Hogan, Vanessa E, Holweg, Cécile T J, Choy, David F, Kummerfeld, Sarah K, Hackney, Jason A, Teng, Y K Onno, Townsend, Michael J, van Laar, Jacob M

“…Personalised healthcare is contingent on the identification of biomarkers that represent disease relevant pathways and predict drug response. The authors aimed…”
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Differences in RNA processing underlie the tissue specific phenotype of ISCU myopathy by Sanaker, Petter S., Toompuu, Marina, Hogan, Vanessa E., He, Langping, Tzoulis, Charalampos, Chrzanowska-Lightowlers, Zofia M.A., Taylor, Robert W., Bindoff, Laurence A.

“…Hereditary myopathy with lactic acidosis, or myopathy with exercise intolerance, Swedish type (OMIM # 255125) is caused by mutations in the iron–sulfur cluster…”
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