Search Results - "Hogan, P"

The eosinophil by Rothenberg, Marc E, Hogan, Simon P

“…Eosinophils have been considered end-stage cells involved in host protection against parasites. However, numerous lines of evidence have now changed this…”
Get full text

Intestinal barrier function: Molecular regulation and disease pathogenesis by Groschwitz, Katherine R., BS, Hogan, Simon P., PhD

“…The intestinal epithelium is a single-cell layer that constitutes the largest and most important barrier against the external environment. It acts as a…”
Get full text

Induction of Interleukin-9-Producing Mucosal Mast Cells Promotes Susceptibility to IgE-Mediated Experimental Food Allergy by Chen, Chun-Yu, Lee, Jee-Boong, Liu, Bo, Ohta, Shoichiro, Wang, Pin-Yi, Kartashov, Andrey V., Mugge, Luke, Abonia, J. Pablo, Barski, Artem, Izuhara, Kenji, Rothenberg, Marc E., Finkelman, Fred D., Hogan, Simon P., Wang, Yui-Hsi

“…Experimental IgE-mediated food allergy depends on intestinal anaphylaxis driven by interleukin-9 (IL-9). However, the primary cellular source of IL-9 and the…”
Get full text

The dynamics of the Mississippi River plume: Impact of topography, wind and offshore forcing on the fate of plume waters by Schiller, R. V., Kourafalou, V. H., Hogan, P., Walker, N. D.

“…High‐resolution numerical simulations of the northern Gulf of Mexico region using the Hybrid Coordinate Ocean Model (HYCOM) were employed to investigate the…”
Get full text

New Mixing Diagnostic and Gulf Oil Spill Movement by Mezić, Igor, Loire, S, Fonoberov, Vladimir A, Hogan, P

“…Chaotic advection has served as the paradigm for mixing in fluid flows with simple time dependence. Its skeletal structure is based on analysis of invariant…”
Get full text

Identification of 5‑HT2 Serotonin Receptor Modulators through the Synthesis of a Diverse, Tropane- and Quinuclidine-alkaloid-Inspired Compound Library by Yao, Ruwei, Jensen, Anders A., Bryce-Rogers, Hogan P., Schultz-Knudsen, Katrine, Zhou, Libin, Hovendal, Nicklas P., Pedersen, Henrik, Kubus, Mariusz, Ulven, Trond, Laraia, Luca

“…The recombination of natural product (NP) fragments in unprecedented ways has emerged as an important strategy for bioactive compound discovery. In this…”
Get full text

Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling by Giles, Daniel A, Moreno-Fernandez, Maria E, Stankiewicz, Traci E, Graspeuntner, Simon, Cappelletti, Monica, Wu, David, Mukherjee, Rajib, Chan, Calvin C, Lawson, Matthew J, Klarquist, Jared, Sünderhauf, Annika, Softic, Samir, Kahn, C Ronald, Stemmer, Kerstin, Iwakura, Yoichiro, Aronow, Bruce J, Karns, Rebekah, Steinbrecher, Kris A, Karp, Christopher L, Sheridan, Rachel, Shanmukhappa, Shiva K, Reynaud, Damien, Haslam, David B, Sina, Christian, Rupp, Jan, Hogan, Simon P, Divanovic, Senad

“…Current mouse models of nonalcoholic steatohepatitis are limited, making identification and preclinical testing of new treatments challenging. Housing mice at…”
Get full text

High Thermoelectric Performance via Hierarchical Compositionally Alloyed Nanostructures by Zhao, Li-Dong, Hao, Shiqiang, Lo, Shih-Han, Wu, Chun-I, Zhou, Xiaoyuan, Lee, Yeseul, Li, Hao, Biswas, Kanishka, Hogan, Timothy P, Uher, Ctirad, Wolverton, C, Dravid, Vinayak P, Kanatzidis, Mercouri G

“…Previous efforts to enhance thermoelectric performance have primarily focused on reduction in lattice thermal conductivity caused by broad-based phonon…”
Get full text

Flipping the switch on the hub cell: Islet desynchronization through cell silencing by Hogan, Janita P, Peercy, Bradford E

“…Pancreatic β cells, responsible for secreting insulin into the bloodstream and maintaining glucose homeostasis, are organized in the islets of Langerhans as…”
Get full text

High Performance Thermoelectrics from Earth-Abundant Materials: Enhanced Figure of Merit in PbS by Second Phase Nanostructures by Zhao, Li-Dong, Lo, Shih-Han, He, Jiaqing, Li, Hao, Biswas, Kanishka, Androulakis, John, Wu, Chun-I, Hogan, Timothy P, Chung, Duck-Young, Dravid, Vinayak P, Kanatzidis, Mercouri G

“…Lead sulfide, a compound consisting of elements with high natural abundance, can be converted into an excellent thermoelectric material. We report extensive…”
Get full text

High ZT in p‑Type (PbTe)1–2x (PbSe) x ­(PbS) x Thermoelectric Materials by Korkosz, Rachel J, Chasapis, Thomas C, Lo, Shih-han, Doak, Jeff W, Kim, Yoon Jun, Wu, Chun-I, Hatzikraniotis, Euripidis, Hogan, Timothy P, Seidman, David N, Wolverton, Chris, Dravid, Vinayak P, Kanatzidis, Mercouri G

“…Lead chalcogenide thermoelectric systems have been shown to reach record high figure of merit values via modification of the band structure to increase the…”
Get full text

IL-25 and CD4+ TH2 cells enhance type 2 innate lymphoid cell–derived IL-13 production, which promotes IgE-mediated experimental food allergy by Lee, Jee-Boong, Chen, Chun-Yu, Liu, Bo, Mugge, Luke, Angkasekwinai, Pornpimon, Facchinetti, Valeria, Dong, Chen, Liu, Yong-Jun, Rothenberg, Marc E., Hogan, Simon P., Finkelman, Fred D., Wang, Yui-Hsi

“…Food-mediated allergic reactions have emerged as a major health problem. The underlying mechanisms that promote uncontrolled type 2 immune responses to dietary…”
Get full text

Modeling TH2 responses and airway inflammation to understand fundamental mechanisms regulating the pathogenesis of asthma by Foster, Paul S., Maltby, Steven, Rosenberg, Helene F., Tay, Hock L., Hogan, Simon P., Collison, Adam M., Yang, Ming, Kaiko, Gerard E., Hansbro, Philip M., Kumar, Rakesh K., Mattes, Joerg

“…Summary In this review, we highlight experiments conducted in our laboratories that have elucidated functional roles for CD4+ T‐helper type‐2 lymphocytes (TH2…”
Get full text

Eosinophils: Biological Properties and Role in Health and Disease by HOGAN, SIMON P., ROSENBERG, HELENE F., MOQBEL, REDWAN, PHIPPS, SIMON, FOSTER, PAUL S., LACY, PAIGE, KAY, A. BARRY, ROTHENBERG, MARC E.

“…SUMMARY Eosinophils are pleiotropic multifunctional leukocytes involved in initiation and propagation of diverse inflammatory responses, as well as modulators…”
Get full text

The Added Value of Different Data Types for Calibrating and Testing a Hydrologic Model in a Small Catchment by Széles, B., Parajka, J., Hogan, P., Silasari, R., Pavlin, L., Strauss, P., Blöschl, G.

“…This study investigated the added value of different data for calibrating a runoff model for small basins. The analysis was performed in the 66 ha Hydrological…”
Get full text

Intestinal goblet cells sample and deliver lumenal antigens by regulated endocytic uptake and transcytosis by Gustafsson, Jenny K, Davis, Jazmyne E, Rappai, Tracy, McDonald, Keely G, Kulkarni, Devesha H, Knoop, Kathryn A, Hogan, Simon P, Fitzpatrick, James Aj, Lencer, Wayne I, Newberry, Rodney D

“…Intestinal goblet cells maintain the protective epithelial barrier through mucus secretion and yet sample lumenal substances for immune processing through…”
Get full text

Digital Mental Health Interventions for Depression: Scoping Review of User Engagement by Lipschitz, Jessica M, Van Boxtel, Rachel, Torous, John, Firth, Joseph, Lebovitz, Julia G, Burdick, Katherine E, Hogan, Timothy P

“…While many digital mental health interventions (DMHIs) have been found to be efficacious, patient engagement with DMHIs has increasingly emerged as a concern…”
Get full text

Large Enhancements in the Thermoelectric Power Factor of Bulk PbTe at High Temperature by Synergistic Nanostructuring by Sootsman, Joseph R, Kong, Huijun, Uher, Ctirad, D'Angelo, Jonathan James, Wu, Chun -I, Hogan, Timothy P, Caillat, Thierry, Kanatzidis, Mercouri G

“…Co‐nanostructuring of PbTe with two kinds of metallic nanoparticles (Pb and Sb) can significantly increase its power factor at high temperatures (up to 87 % at…”
Get full text

Importance of Cytokines in Murine Allergic Airway Disease and Human Asthma by Finkelman, Fred D, Hogan, Simon P, Hershey, Gurjit K. Khurana, Rothenberg, Marc E, Wills-Karp, Marsha

“…Asthma is a common, disabling inflammatory respiratory disease that has increased in frequency and severity in developed nations. We review studies of murine…”
Get full text

Lipopolysaccharide suppresses IgE‐mast cell‐mediated reactions by Wang, N., McKell, M., Dang, A., Yamani, A., Waggoner, L., Vanoni, S., Noah, T., Wu, D., Kordowski, A., Köhl, J., Hoebe, K., Divanovic, S., Hogan, S. P.

“…Summary Background Clinical and experimental analyses have identified a central role for IgE/FcεRI/mast cells in promoting IgE‐mediated anaphylaxis. Recent…”
Get full text