Search Results - "Hogan, Louise E."

HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study by Henrich, Timothy J, Hatano, Hiroyu, Bacon, Oliver, Hogan, Louise E, Rutishauser, Rachel, Hill, Alison, Kearney, Mary F, Anderson, Elizabeth M, Buchbinder, Susan P, Cohen, Stephanie E, Abdel-Mohsen, Mohamed, Pohlmeyer, Christopher W, Fromentin, Remi, Hoh, Rebecca, Liu, Albert Y, McCune, Joseph M, Spindler, Jonathan, Metcalf-Pate, Kelly, Hobbs, Kristen S, Thanh, Cassandra, Gibson, Erica A, Kuritzkes, Daniel R, Siliciano, Robert F, Price, Richard W, Richman, Douglas D, Chomont, Nicolas, Siliciano, Janet D, Mellors, John W, Yukl, Steven A, Blankson, Joel N, Liegler, Teri, Deeks, Steven G

“…It is unknown if extremely early initiation of antiretroviral therapy (ART) may lead to long-term ART-free HIV remission or cure. As a result, we studied 2…”
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Increased HIV-1 transcriptional activity and infectious burden in peripheral blood and gut-associated CD4+ T cells expressing CD30 by Hogan, Louise E, Vasquez, Joshua, Hobbs, Kristen S, Hanhauser, Emily, Aguilar-Rodriguez, Brandon, Hussien, Rajaa, Thanh, Cassandra, Gibson, Erica A, Carvidi, Alexander B, Smith, Louis C B, Khan, Shahzada, Trapecar, Martin, Sanjabi, Shomyseh, Somsouk, Ma, Stoddart, Cheryl A, Kuritzkes, Daniel R, Deeks, Steven G, Henrich, Timothy J

“…HIV-1-infected cells persist indefinitely despite the use of combination antiretroviral therapy (ART), and novel therapeutic strategies to target and purge…”
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Rapid development of HIV elite control in a patient with acute infection by Morley, Deirdre, Lambert, John S, Hogan, Louise E, De Gascun, Cillian, Redmond, Niamh, Rutishauser, Rachel L, Thanh, Cassandra, Gibson, Erica A, Hobbs, Kristen, Bakkour, Sonia, Busch, Michael P, Farrell, Jeremy, McGetrick, Padraig, Henrich, Timothy J

“…Abstract Background Elite controllers (EC), a small subset of the HIV-positive population (< 1%), suppress HIV viremia below the limit of quantification of…”
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Human Herpes Virus 8 in HIV-1 infected individuals receiving cancer chemotherapy and stem cell transplantation by Hogan, Louise E, Hanhauser, Emily, Hobbs, Kristen S, Palmer, Christine D, Robles, Yvonne, Jost, Stephanie, LaCasce, Anne S, Abramson, Jeremy, Hamdan, Ayad, Marty, Francisco M, Kuritzkes, Daniel R, Henrich, Timothy J

“…Human Herpes Virus 8 (HHV8) can cause Kaposi's Sarcoma (KS) in immunosuppressed individuals. However, little is known about the association between…”
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High-throughput Characterization of HIV-1 Reservoir Reactivation Using a Single-Cell-in-Droplet PCR Assay by Yucha, Robert W., Hobbs, Kristen S., Hanhauser, Emily, Hogan, Louise E., Nieves, Wildaliz, Ozen, Mehmet O., Inci, Fatih, York, Vanessa, Gibson, Erica A., Thanh, Cassandra, Shafiee, Hadi, El Assal, Rami, Kiselinova, Maja, Robles, Yvonne P., Bae, Helen, Leadabrand, Kaitlyn S., Wang, ShuQi, Deeks, Steven G., Kuritzkes, Daniel R., Demirci, Utkan, Henrich, Timothy J.

“…Reactivation of latent viral reservoirs is on the forefront of HIV-1 eradication research. However, it is unknown if latency reversing agents (LRAs) increase…”
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Correction to: Rapid development of HIV elite control in a patient with acute infection by Morley, Deirdre, Lambert, John S, Hogan, Louise E, De Gascun, Cillian, Redmond, Niamh, Rutishauser, Rachel L, Thanh, Cassandra, Gibson, Erica A, Hobbs, Kristen, Bakkour, Sonia, Busch, Michael P, Farrell, Jeremy, McGetrick, Padraig, Henrich, Timothy J

“…After publication of the original article [1], we were notified in Table 1 a column should be removed…”
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Cerebrospinal fluid soluble CD30 elevation despite suppressive antiretroviral therapy in individuals living with HIV-1 by Peluso, Michael J, Thanh, Cassandra, Prator, Cecilia A, Hogan, Louise E, Arechiga, Victor M, Stephenson, Sophie, Norris, Philip J, Di Germanio, Clara, Fuchs, Dietmar, Zetterberg, Henrik, Deeks, Steven G, Gisslén, Magnus, Price, Richard W, Henrich, Timothy J

“…Objectives: The aim of this study was to assess soluble CD30 (sCD30), a protein that colocalises with HIV-1 RNA and DNA in lymphoid cells and tissues, in…”
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NK-cell activation is associated with increased HIV transcriptional activity following allogeneic hematopoietic cell transplantation by Hogan, Louise E., Körner, Christian, Hobbs, Kristen, Simoneau, Camille R., Thanh, Cassandra, Gibson, Erica A., Palmer, Christine D., Pandit, Alisha, Marty, Francisco M., Kuritzkes, Daniel R., Jost, Stephanie, Ritz, Jerome, Henrich, Timothy J.

“…•Graft-versus-host effects may lead to HIV-1 reactivation and cell death of infected pre-HCT CD4+ T cells.•Natural killer cell activation correlates with in…”
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A humanized mouse-based HIV-1 viral outgrowth assay with higher sensitivity than in vitro qVOA in detecting latently infected cells from individuals on ART with undetectable viral loads by Charlins, Paige, Schmitt, Kimberly, Remling-Mulder, Leila, Hogan, Louise E, Hanhauser, Emily, Hobbs, Kristen S, Hecht, Frederick, Deeks, Steven G, Henrich, Timothy J, Akkina, Ramesh

“…Abstract Assays that can verify full viral eradication are essential in the context of achieving a cure for HIV/AIDS. In vitro quantitative viral out growth…”
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Expression of the innate immune receptor LILRB5 on monocytes is associated with mycobacteria exposure by Hogan, Louise E., Jones, Des C., Allen, Rachel L.

“…Antigen presenting cells (APC) are critical components of innate immunity and consequently shape the adaptive response. Leukocyte Ig Like Receptors (LILR) are…”
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Everolimus, an mTORC1/2 inhibitor, in ART‐suppressed individuals who received solid organ transplantation: A prospective study by Henrich, Timothy J., Schreiner, Corinna, Cameron, Cheryl, Hogan, Louise E., Richardson, Brian, Rutishauser, Rachel L., Deitchman, Amelia N., Chu, Simon, Rogers, Rodney, Thanh, Cassandra, Gibson, Erica A., Zarinsefat, Arya, Bakkour, Sonia, Aweeka, Francesca, Busch, Michael P., Liegler, Teri, Baker, Christopher, Milush, Jeffrey, Deeks, Steven G., Stock, Peter G.

“…Pharmacologic inhibition of the mammalian target of rapamycin (mTOR) in the setting of renal transplantation has previously been associated with lower human…”
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Human Immunodeficiency Virus Type 1 Persistence Following Systemic Chemotherapy for Malignancy by Henrich, Timothy J., Hobbs, Kristen S., Hanhauser, Emily, Scully, Eileen, Hogan, Louise E., Robles, Yvonne P., Leadabrand, Kaitlyn S., Marty, Francisco M., Palmer, Christine D., Jost, Stephanie, Körner, Christian, Li, Jonathan Z., Gandhi, Rajesh T., Hamdan, Ayad, Abramson, Jeremy, LaCasce, Ann S., Kuritzkes, Daniel R.

“…Background. Systemic chemotherapies for various malignancies have been shown to significantly, yet transiently, decrease numbers of CD4+ T lymphocytes, a major…”
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Evaluating a New Class of AKT/mTOR Activators for HIV Latency Reversing Activity Ex Vivo and In Vivo by Gramatica, Andrea, Schwarzer, Roland, Brantley, William, Varco-Merth, Benjamin, Sperber, Hannah S, Hull, Philip A, Montano, Mauricio, Migueles, Stephen A, Rosenthal, Danielle, Hogan, Louise E, Johnson, Jeffrey R, Packard, Thomas A, Grimmett, Zachary W, Herzig, Eytan, Besnard, Emilie, Nekorchuk, Michael, Hsiao, Feng, Deeks, Steven G, Snape, Michael, Kiernan, Bernard, Roan, Nadia R, Lifson, Jeffrey D, Estes, Jacob D, Picker, Louis J, Verdin, Eric, Krogan, Nevan J, Henrich, Timothy J, Connors, Mark, Ott, Melanie, Pillai, Satish K, Okoye, Afam A, Greene, Warner C

“…An ability to activate latent HIV-1 expression could benefit many HIV cure strategies, but the first generation of latency reversing agents (LRAs) has proven…”
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Elucidating the Burden of HIV in Tissues Using Multiplexed Immunofluorescence and In Situ Hybridization: Methods for the Single-Cell Phenotypic Characterization of Cells Harboring HIV In Situ by Vasquez, Joshua J., Hussien, Rajaa, Aguilar-Rodriguez, Brandon, Junger, Henrik, Dobi, Dejan, Henrich, Timothy J., Thanh, Cassandra, Gibson, Erica, Hogan, Louise E., McCune, Joseph, Hunt, Peter W., Stoddart, Cheryl A., Laszik, Zoltan G.

“…Persistent tissue reservoirs of HIV present a major barrier to cure. Defining subsets of infected cells in tissues is a major focus of HIV cure research…”
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Transient loss of detectable HIV-1 RNA following brentuximab vedotin anti-CD30 therapy for Hodgkin lymphoma by Wang, Chia-Ching, Thanh, Cassandra, Gibson, Erica A., Ball-Burack, Maya, Hogan, Louise E., Descours, Benjamin, Jones, Norman, Carvidi, Alexander B., Munter, Sadie, Bakkour, Sonia, Busch, Michael P., Milush, Jeffrey M., Deeks, Steven G., Henrich, Timothy J.

“…Key Points Anti-CD30 therapy for Hodgkin lymphoma led to transient loss of detectable CD4+ T-cell HIV RNA and a decrease in residual plasma viremia. Targeting…”
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CD32-RNA Co-localizes with HIV-RNA in CD3+ Cells Found within Gut Tissues from Viremic and ART-Suppressed Individuals by Vásquez, Joshua J, Aguilar-Rodriguez, Brandon L, Rodriguez, Leonardo, Hogan, Louise E, Somsouk, Ma, McCune, Joseph M, Deeks, Steven G, Laszik, Zoltan G, Hunt, Peter W, Henrich, Timothy J

“…Identifying biomarkers for cells harboring replication-competent HIV is a major research priority. Recently, there have been mixed reports addressing the…”
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Comparison of new and 3-month-old brush heads in the removal of plaque using a powered toothbrush by Hogan, Louise M. E., Daly, Christopher G., Curtis, Brad H.

“…Aim: To compare the effectiveness of new and 3‐month‐old worn brush heads in plaque removal using a rotation–oscillation‐powered toothbrush. Material and…”
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A humanized mouse-based HIV-1 viral outgrowth assay with higher sensitivity than in vitro VOA in detecting latently infected cells from individuals on ART with undetectable viral loads by Charlins, Paige, Schmitt, Kimberly, Remling-Mulder, Leila, Hogan, Louise E., Hanhauser, Emily, Hobbs, Kristen S., Hecht, Frederick, Deeks, Steven G., Henrich, Timothy J., Akkina, Ramesh

“…Assays that can verify full viral eradication are essential in the context of achieving a cure for HIV/AIDS. In vitro quantitative viral out growth assays…”
Get full text

Increased HIV-1 transcriptional activity and infectious burden in peripheral blood and gut-associated CD4.sup.+ T cells expressing CD30 by Hogan, Louise E, Vasquez, Joshua, Hobbs, Kristen S, Hanhauser, Emily, Aguilar-Rodriguez, Brandon, Hussien, Rajaa, Thanh, Cassandra, Gibson, Erica A, Carvidi, Alexander B, Smith, Louis C. B, Khan, Shahzada, Trapecar, Martin, Sanjabi, Shomyseh, Somsouk, Ma, Stoddart, Cheryl A, Kuritzkes, Daniel R, Deeks, Steven G, Henrich, Timothy J

“…HIV-1-infected cells persist indefinitely despite the use of combination antiretroviral therapy (ART), and novel therapeutic strategies to target and purge…”
Get full text

HIV-1 persistence following extremely early initiation of antiretroviral therapy by Henrich, Timothy J, Hatano, Hiroyu, Bacon, Oliver, Hogan, Louise E, Rutishauser, Rachel, Hill, Alison, Kearney, Mary F, Anderson, Elizabeth M, Buchbinder, Susan P, Cohen, Stephanie E, Abdel-Mohsen, Mohamed, Pohlmeyer, Christopher W, Fromentin, Remi, Hoh, Rebecca, Liu, Albert Y, McCune, Joseph M, Spindler, Jonathan, Metcalf-Pate, Kelly, Hobbs, Kristen S, Thanh, Cassandra, Gibson, Erica A, Kuritzkes, Daniel R, Siliciano, Robert F, Price, Richard W, Richman, Douglas D, Chomont, Nicolas, Siliciano, Janet D, Mellors, John W, Yukl, Steven A, Blankson, Joel N, Liegler, Teri, Deeks, Steven G

“…Background It is unknown if extremely early initiation of antiretroviral therapy (ART) may lead to long-term ART-free HIV remission or cure. As a result, we…”
Get full text