Search Results - "Hogan, Jason M"

A targeted proteomics-based pipeline for verification of biomarkers in plasma by Paulovich, Amanda G, Whiteaker, Jeffrey R, Lin, Chenwei, Kennedy, Jacob, Hou, Liming, Trute, Mary, Sokal, Izabela, Yan, Ping, Schoenherr, Regine M, Zhao, Lei, Voytovich, Uliana J, Kelly-Spratt, Karen S, Krasnoselsky, Alexei, Gafken, Philip R, Hogan, Jason M, Jones, Lisa A, Wang, Pei, Amon, Lynn, Chodosh, Lewis A, Nelson, Peter S, McIntosh, Martin W, Kemp, Christopher J

“…Prioritizing candidate biomarkers for verification remains a formidable obstacle to the translation of protein diagnostics to clinical applications. Whiteaker…”
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A Proteomics Platform Combining Depletion, Multi-lectin Affinity Chromatography (M-LAC), and Isoelectric Focusing to Study the Breast Cancer Proteome by Zeng, Zhi, Hincapie, Marina, Pitteri, Sharon J, Hanash, Samir, Schalkwijk, Joost, Hogan, Jason M, Wang, Hong, Hancock, William S

“…The discovery of breast cancer associated plasma/serum biomarkers is important for early diagnosis, disease mechanism elucidation, and determination of…”
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Design and characterization of mouse IgG1 and IgG2a bispecific antibodies for use in syngeneic models by Wang, Feng, Tsai, Jordan C, Davis, Jonathan H, Chau, Bryant, Dong, Jia, West, Sean M, Hogan, Jason M, Wheeler, Matthew L, Bee, Christine, Morishige, Winse, Cayton, Thomas, David-Brown, Donata, Zhang, Chengyue, Kozhich, Alexander, Sproul, Tim, Dollinger, Gavin, Rajpal, Arvind, Strop, Pavel

“…The development of antibody therapeutics relies on animal models that accurately recapitulate disease biology. Syngeneic mouse models are increasingly used…”
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Antibody blockade of CD96 by distinct molecular mechanisms by Lee, Peter S, Chau, Bryant, Barman, Ishita, Bee, Christine, Jashnani, Aarti, Hogan, Jason M, Aguilar, Barbara, Dollinger, Gavin, Rajpal, Arvind, Strop, Pavel

“…The molecular interactions of mouse CD96 to CD155 ligand and to two surrogate antibodies have been investigated. Biophysical and structural studies demonstrate…”
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Effective Inertial Frame in an Atom Interferometric Test of the Equivalence Principle by Overstreet, Chris, Asenbaum, Peter, Kovachy, Tim, Notermans, Remy, Hogan, Jason M, Kasevich, Mark A

“…In an ideal test of the equivalence principle, the test masses fall in a common inertial frame. A real experiment is affected by gravity gradients, which…”
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Complementary Structural Information from a Tryptic N-Linked Glycopeptide via Electron Transfer Ion/Ion Reactions and Collision-Induced Dissociation by Hogan, Jason M, Pitteri, Sharon J, Chrisman, Paul A, McLuckey, Scott A

“…Glycosylation is an important post-translational modification. Analysis of glycopeptides is difficult using collision-induced dissociation, as it typically…”
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New method for gravitational wave detection with atomic sensors by Graham, Peter W, Hogan, Jason M, Kasevich, Mark A, Rajendran, Surjeet

“…Laser frequency noise is a dominant noise background for the detection of gravitational waves using long-baseline optical interferometry. Amelioration of this…”
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Phase Shift in an Atom Interferometer due to Spacetime Curvature across its Wave Function by Asenbaum, Peter, Overstreet, Chris, Kovachy, Tim, Brown, Daniel D, Hogan, Jason M, Kasevich, Mark A

“…Spacetime curvature induces tidal forces on the wave function of a single quantum system. Using a dual light-pulse atom interferometer, we measure a phase…”
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The development of an integrated platform to identify breast cancer glycoproteome changes in human serum by Zeng, Zhi, Hincapie, Marina, Haab, Brian B., Hanash, Samir, Pitteri, Sharon J., Kluck, Steven, Hogan, Jason M., Kennedy, Jacob, Hancock, William S.

“…Protein glycosylation represents one of the major post-translational modifications and can have significant effects on protein function. Moreover, changes in…”
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Large Momentum Transfer Clock Atom Interferometry on the 689 nm Intercombination Line of Strontium by Rudolph, Jan, Wilkason, Thomas, Nantel, Megan, Swan, Hunter, Holland, Connor M, Jiang, Yijun, Garber, Benjamin E, Carman, Samuel P, Hogan, Jason M

“…We report the first realization of large momentum transfer (LMT) clock atom interferometry. Using single-photon interactions on the strontium…”
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Multiaxis inertial sensing with long-time point source atom interferometry by Dickerson, Susannah M, Hogan, Jason M, Sugarbaker, Alex, Johnson, David M S, Kasevich, Mark A

“…We show that light-pulse atom interferometry with atomic point sources and spatially resolved detection enables multiaxis (two rotation, one acceleration)…”
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Matter wave lensing to picokelvin temperatures by Kovachy, Tim, Hogan, Jason M, Sugarbaker, Alex, Dickerson, Susannah M, Donnelly, Christine A, Overstreet, Chris, Kasevich, Mark A

“…Using a matter wave lens and a long time of flight, we cool an ensemble of ^{87}Rb atoms in two dimensions to an effective temperature of less than…”
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Atom Interferometry with Floquet Atom Optics by Wilkason, Thomas, Nantel, Megan, Rudolph, Jan, Jiang, Yijun, Garber, Benjamin E., Swan, Hunter, Carman, Samuel P., Abe, Mahiro, Hogan, Jason M.

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Testing general relativity with atom interferometry by Dimopoulos, Savas, Graham, Peter W, Hogan, Jason M, Kasevich, Mark A

“…The unprecedented precision of atom interferometry will soon lead to laboratory tests of general relativity to levels that will rival or exceed those reached…”
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Enhanced atom interferometer readout through the application of phase shear by Sugarbaker, Alex, Dickerson, Susannah M, Hogan, Jason M, Johnson, David M S, Kasevich, Mark A

“…We present a method for determining the phase and contrast of a single shot of an atom interferometer. The application of a phase shear across the atom…”
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Gravitational wave detection with atom interferometry by Dimopoulos, Savas, Graham, Peter W., Hogan, Jason M., Kasevich, Mark A., Rajendran, Surjeet

“…We propose two distinct atom interferometer gravitational wave detectors, one terrestrial and another satellite-based, utilizing the core technology of the…”
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Preclinical Characterization of Relatlimab, a Human LAG-3-Blocking Antibody, Alone or in Combination with Nivolumab by Thudium, Kent, Selby, Mark, Zorn, Julie A, Rak, Gregory, Wang, Xi-Tao, Bunch, Roderick Todd, Hogan, Jason M, Strop, Pavel, Korman, Alan J

“…Novel therapeutic approaches combining immune-checkpoint inhibitors are needed to improve clinical outcomes for patients with cancer. Lymphocyte-activation…”
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Residue-Level Characterization of Antibody Binding Epitopes Using Carbene Chemical Footprinting by Hogan, Jason M, Lee, Peter S, Wong, Susan C, West, Sean M, Morishige, Winse H, Bee, Christine, Tapia, Gamze Camdere, Rajpal, Arvind, Strop, Pavel, Dollinger, Gavin

“…Characterization of antibody binding epitopes is an important factor in therapeutic drug discovery, as the binding site determines and drives antibody…”
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An atomic gravitational wave interferometric sensor in low earth orbit (AGIS-LEO) by Hogan, Jason M., Johnson, David M. S., Dickerson, Susannah, Kovachy, Tim, Sugarbaker, Alex, Chiow, Sheng-wey, Graham, Peter W., Kasevich, Mark A., Saif, Babak, Rajendran, Surjeet, Bouyer, Philippe, Seery, Bernard D., Feinberg, Lee, Keski-Kuha, Ritva

“…We propose an atom interferometer gravitational wave detector in low Earth orbit (AGIS-LEO). Gravitational waves can be observed by comparing a pair of atom…”
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Impact of Drug Conjugation on Thermal and Metabolic Stabilities of Aglycosylated and N‑Glycosylated Antibodies by Yamazoe, Sayumi, Kotapati, Srikanth, Hogan, Jason M, West, Sean M, Deng, Xiaodi A, Diong, SJ, Arbanas, Jaren, Nguyen, Thien Anh, Jashnani, Aarti, Gupta, Diksha, Rajpal, Arvind, Dollinger, Gavin, Strop, Pavel

“…N-linked glycosylation is one of the most common and complex posttranslational modifications that govern the biological functions and physicochemical…”
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