Search Results - "Hogan, Benjamin M"

How to Plumb a Pisces: Understanding Vascular Development and Disease Using Zebrafish Embryos by Hogan, Benjamin M., Schulte-Merker, Stefan

“…Our vasculature plays diverse and critical roles in homeostasis and disease. In recent decades, the use of zebrafish has driven our understanding of vascular…”
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Deep conservation of the enhancer regulatory code in animals by Wong, Emily S, Zheng, Dawei, Tan, Siew Z, Bower, Neil L, Garside, Victoria, Vanwalleghem, Gilles, Gaiti, Federico, Scott, Ethan, Hogan, Benjamin M, Kikuchi, Kazu, McGlinn, Edwina, Francois, Mathias, Degnan, Bernard M

“…Interactions of transcription factors (TFs) with DNA regulatory sequences, known as enhancers, specify cell identity during animal development. Unlike TFs, the…”
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Endothelial Cell Dynamics in Vascular Development: Insights From Live-Imaging in Zebrafish by Okuda, Kazuhide S., Hogan, Benjamin M.

“…The formation of the vertebrate vasculature involves the acquisition of endothelial cell identities, sprouting, migration, remodeling and maturation of…”
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Vegfc Regulates Bipotential Precursor Division and Prox1 Expression to Promote Lymphatic Identity in Zebrafish by Koltowska, Katarzyna, Lagendijk, Anne Karine, Pichol-Thievend, Cathy, Fischer, Johanna C., Francois, Mathias, Ober, Elke A., Yap, Alpha S., Hogan, Benjamin M.

“…Lymphatic vessels arise chiefly from preexisting embryonic veins. Genetic regulators of lymphatic fate are known, but how dynamic cellular changes contribute…”
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Atypical cadherin FAT4 orchestrates lymphatic endothelial cell polarity in response to flow by Betterman, Kelly L, Sutton, Drew L, Secker, Genevieve A, Kazenwadel, Jan, Oszmiana, Anna, Lim, Lillian, Miura, Naoyuki, Sorokin, Lydia, Hogan, Benjamin M, Kahn, Mark L, McNeill, Helen, Harvey, Natasha L

“…The atypical cadherin FAT4 has established roles in the regulation of planar cell polarity and Hippo pathway signaling that are cell context dependent. The…”
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Getting out and about: the emergence and morphogenesis of the vertebrate lymphatic vasculature by Koltowska, Katarzyna, Betterman, Kelly L, Harvey, Natasha L, Hogan, Benjamin M

“…The lymphatic vascular system develops from the pre-existing blood vasculature of the vertebrate embryo. New insights into lymphatic vascular development have…”
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Vegfd modulates both angiogenesis and lymphangiogenesis during zebrafish embryonic development by Bower, Neil I, Vogrin, Adam J, Le Guen, Ludovic, Chen, Huijun, Stacker, Steven A, Achen, Marc G, Hogan, Benjamin M

“…Vascular endothelial growth factors (VEGFs) control angiogenesis and lymphangiogenesis during development and in pathological conditions. In the zebrafish…”
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A blood capillary plexus-derived population of progenitor cells contributes to genesis of the dermal lymphatic vasculature during embryonic development by Pichol-Thievend, Cathy, Betterman, Kelly L, Liu, Xiaolei, Ma, Wanshu, Skoczylas, Renae, Lesieur, Emmanuelle, Bos, Frank L, Schulte, Dorte, Schulte-Merker, Stefan, Hogan, Benjamin M, Oliver, Guillermo, Harvey, Natasha L, Francois, Mathias

“…Despite the essential role of the lymphatic vasculature in tissue homeostasis and disease, knowledge of the organ-specific origins of lymphatic endothelial…”
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Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish by Lagendijk, Anne Karine, Gomez, Guillermo A., Baek, Sungmin, Hesselson, Daniel, Hughes, William E., Paterson, Scott, Conway, Daniel E., Belting, Heinz-Georg, Affolter, Markus, Smith, Kelly A., Schwartz, Martin A., Yap, Alpha S., Hogan, Benjamin M.

“…Forces play diverse roles in vascular development, homeostasis and disease. VE-cadherin at endothelial cell-cell junctions links the contractile acto-myosin…”
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Ccbe1 regulates Vegfc-mediated induction of Vegfr3 signaling during embryonic lymphangiogenesis by Le Guen, Ludovic, Karpanen, Terhi, Schulte, Dörte, Harris, Nicole C, Koltowska, Katarzyna, Roukens, Guy, Bower, Neil I, van Impel, Andreas, Stacker, Steven A, Achen, Marc G, Schulte-Merker, Stefan, Hogan, Benjamin M

“…The VEGFC/VEGFR3 signaling pathway is essential for lymphangiogenesis (the formation of lymphatic vessels from pre-existing vasculature) during embryonic…”
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Mechanotransduction activates RhoA in the neighbors of apoptotic epithelial cells to engage apical extrusion by Duszyc, Kinga, Gomez, Guillermo A., Lagendijk, Anne K., Yau, Mei-Kwan, Nanavati, Bageshri Naimish, Gliddon, Briony L., Hall, Thomas E., Verma, Suzie, Hogan, Benjamin M., Pitson, Stuart M., Fairlie, David P., Parton, Robert G., Yap, Alpha S.

“…Epithelia must eliminate apoptotic cells to preserve tissue barriers and prevent inflammation.1 Several different mechanisms exist for apoptotic clearance,…”
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Blood vessel occlusion by Cryptococcus neoformans is a mechanism for haemorrhagic dissemination of infection by Gibson, Josie F, Bojarczuk, Aleksandra, Evans, Robert J, Kamuyango, Alfred Alinafe, Hotham, Richard, Lagendijk, Anne K, Hogan, Benjamin M, Ingham, Philip W, Renshaw, Stephen A, Johnston, Simon A

“…Meningitis caused by infectious pathogens is associated with vessel damage and infarct formation, however the physiological cause is often unknown…”
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Junction-based lamellipodia drive endothelial cell rearrangements in vivo via a VE-cadherin-F-actin based oscillatory cell-cell interaction by Paatero, Ilkka, Sauteur, Loïc, Lee, Minkyoung, Lagendijk, Anne K., Heutschi, Daniel, Wiesner, Cora, Guzmán, Camilo, Bieli, Dimitri, Hogan, Benjamin M., Affolter, Markus, Belting, Heinz-Georg

“…Angiogenesis and vascular remodeling are driven by extensive endothelial cell movements. Here, we present in vivo evidence that endothelial cell movements are…”
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Zebrafish facial lymphatics develop through sequential addition of venous and non‐venous progenitors by Eng, Tiffany CY, Chen, Wenxuan, Okuda, Kazuhide S, Misa, June P, Padberg, Yvonne, Crosier, Kathryn E, Crosier, Philip S, Hall, Christopher J, Schulte‐Merker, Stefan, Hogan, Benjamin M, Astin, Jonathan W

“…Lymphatic vessels are known to be derived from veins; however, recent lineage‐tracing experiments propose that specific lymphatic networks may originate from…”
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Vegfc/Flt4 signalling is suppressed by Dll4 in developing zebrafish intersegmental arteries by Hogan, Benjamin M., Herpers, Robert, Witte, Merlijn, Heloterä, Hanna, Alitalo, Kari, Duckers, Henricus J., Schulte-Merker, Stefan

“…The development of arteries, veins and lymphatics from pre-existing vessels are intimately linked processes controlled by a number of well-studied…”
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Peri-arterial specification of vascular mural cells from naïve mesenchyme requires Notch signaling by Ando, Koji, Wang, Weili, Peng, Di, Chiba, Ayano, Lagendijk, Anne K, Barske, Lindsey, Crump, J Gage, Stainier, Didier Y R, Lendahl, Urban, Koltowska, Katarzyna, Hogan, Benjamin M, Fukuhara, Shigetomo, Mochizuki, Naoki, Betsholtz, Christer

“…Mural cells (MCs) are essential for blood vessel stability and function; however, the mechanisms that regulate MC development remain incompletely understood,…”
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Src kinases relax adherens junctions between the neighbors of apoptotic cells to permit apical extrusion by Teo, Jessica L, Tomatis, Vanesa M, Coburn, Luke, Lagendijk, Anne K, Schouwenaar, Irin-Maya, Budnar, Srikanth, Hall, Thomas E, Verma, Suzie, McLachlan, Robert W, Hogan, Benjamin M, Parton, Robert G, Yap, Alpha S, Gomez, Guillermo A

“…Epithelia can eliminate apoptotic cells by apical extrusion. This is a complex morphogenetic event where expulsion of the apoptotic cell is accompanied by…”
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Visualization and Tools for Analysis of Zebrafish Lymphatic Development by Okuda, Kazuhide S, Baek, Sungmin, Hogan, Benjamin M

“…The accessibility and optical transparency of the zebrafish embryo offers a unique platform for live-imaging of developmental lymphangiogenesis. Transgenic…”
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mafba and mafbb differentially regulate lymphatic endothelial cell migration in topographically distinct manners by Arnold, Hannah, Panara, Virginia, Hußmann, Melina, Filipek-Gorniok, Beata, Skoczylas, Renae, Ranefall, Petter, Gloger, Marleen, Allalou, Amin, Hogan, Benjamin M., Schulte-Merker, Stefan, Koltowska, Katarzyna

“…Lymphangiogenesis, formation of lymphatic vessels from pre-existing vessels, is a dynamic process that requires cell migration. Regardless of location,…”
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Evolutionary Differences in the Vegf/Vegfr Code Reveal Organotypic Roles for the Endothelial Cell Receptor Kdr in Developmental Lymphangiogenesis by Vogrin, Adam J., Bower, Neil I., Gunzburg, Menachem J., Roufail, Sally, Okuda, Kazuhide S., Paterson, Scott, Headey, Stephen J., Stacker, Steven A., Hogan, Benjamin M., Achen, Marc G.

“…Lymphatic vascular development establishes embryonic and adult tissue fluid balance and is integral in disease. In diverse vertebrate organs, lymphatic vessels…”
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