Search Results - "Hogan, Ann K"
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A Non-canonical Pathway from Cochlea to Brain Signals Tissue-Damaging Noise
Published in Current biology (02-03-2015)“…Intense noise damages the cochlear organ of Corti, particularly the outer hair cells (OHCs) [1]; however, this epithelium is not innervated by nociceptors of…”
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Reduce, Retain, Recycle: Mechanisms for Promoting Histone Protein Degradation versus Stability and Retention
Published in Molecular and cellular biology (01-06-2021)“…The eukaryotic genome is packaged into chromatin. The nucleosome, the basic unit of chromatin, is composed of DNA coiled around a histone octamer. Histones are…”
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Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1
Published in Nature (London) (01-11-2018)“…The mammalian cochlea contains two types of mechanosensory hair cell that have different and critical functions in hearing. Inner hair cells (IHCs), which have…”
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CENP-A overexpression promotes aneuploidy with karyotypic heterogeneity
Published in The Journal of cell biology (05-04-2021)“…Chromosomal instability (CIN) is a hallmark of many cancers. Restricting the localization of centromeric histone H3 variant CENP-A to centromeres prevents CIN…”
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UBR7 acts as a histone chaperone for post‐nucleosomal histone H3
Published in The EMBO journal (15-12-2021)“…Histone chaperones modulate the stability of histones beginning from histone synthesis, through incorporation into DNA, and during recycling during…”
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Author Correction: Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1
Published in Nature (London) (01-01-2019)“…In Figs. 1e and 2g of this Letter, the labels ‘actin’ and ‘VGLUT3’, respectively, should have been in red instead of green font. This has been corrected online…”
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NOTCH1-driven UBR7 stimulates nucleotide biosynthesis to promote T cell acute lymphoblastic leukemia
Published in Science advances (01-01-2021)“…Ubiquitin protein ligase E3 component N-recognin 7 (UBR7) is the most divergent member of UBR box-containing E3 ubiquitin ligases/recognins that mediate the…”
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Peripheral axons of the adult zebrafish maxillary barbel extensively remyelinate during sensory appendage regeneration
Published in Journal of comparative neurology (1911) (15-12-2012)“…Myelination is a cellular adaptation allowing rapid conduction along axons. We have investigated peripheral axons of the zebrafish maxillary barbel (ZMB), an…”
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