Search Results - "Hoft, G"
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Comparisons of the Humoral and Cellular Immune Responses Induced by Live Attenuated Influenza Vaccine and Inactivated Influenza Vaccine in Adults
Published in Clinical and vaccine immunology (01-01-2017)“…Both live attenuated influenza vaccines (LAIV) and inactivated influenza vaccines (IIV) induce protective immunity against influenza. There is evidence that…”
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Discovering Immune-Mediated Mechanisms of Gastric Carcinogenesis Through Single-Cell RNA Sequencing
Published in Frontiers in immunology (10-06-2022)“…Single-cell RNA sequencing (scRNAseq) technology is still relatively new in the field of gastric cancer immunology but gaining significant traction. This…”
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Obesity-related T cell dysfunction impairs immunosurveillance and increases cancer risk
Published in Nature communications (02-04-2024)“…Obesity is a well-established risk factor for human cancer, yet the underlying mechanisms remain elusive. Immune dysfunction is commonly associated with…”
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Mast Cells as Important Regulators in Autoimmunity and Cancer Development
Published in Frontiers in cell and developmental biology (12-10-2021)“…Mast cells are an essential part of the immune system and are best known as important modulators of allergic and anaphylactic immune responses. Upon…”
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Imprinting of Gut-Homing Receptors on Mtb-Specific Th1 Cells Is Associated with Reduced Lung Homing after Gavage BCG Vaccination of Rhesus Macaques
Published in mBio (25-04-2023)“…Alternative delivery routes of the current Mycobacterium tuberculosis (Mtb) vaccine, intradermally (ID) delivered BCG, may provide better protection against…”
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Two Distinct Etiologies of Gastric Cancer: Infection and Autoimmunity
Published in Frontiers in cell and developmental biology (26-11-2021)“…Gastric cancer is a leading cause of mortality worldwide. The risk of developing gastric adenocarcinoma, which comprises >90% of gastric cancers, is…”
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Diagnostic differentiation of Zika and dengue virus exposure by analyzing T cell receptor sequences from peripheral blood of infected HLA-A2 transgenic mice
Published in PLoS neglected tropical diseases (01-12-2020)“…Zika virus (ZIKV) is a significant global health threat due to its potential for rapid emergence and association with severe congenital malformations during…”
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Host resistance to pulmonary Mycobacterium tuberculosis infection requires CD153 expression
Published in Nature microbiology (01-11-2018)“…Mycobacterium tuberculosis infection (Mtb) is the leading cause of death due to a single infectious agent and is among the top ten causes of all human deaths…”
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Immunogenicity and Efficacy of a Recombinant Human Adenovirus Type 5 Vaccine against Zika Virus
Published in Vaccines (Basel) (07-04-2020)“…Zika virus (ZIKV) is a significant public health concern due to the pathogen's ability to be transmitted by either mosquito bite or sexual transmission,…”
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Inverter harmonic reduction using Walsh function harmonic elimination method
Published in IEEE transactions on power electronics (01-11-1997)“…A pulse-width-modulated (PWM) inverter using the Walsh function harmonic elimination method is proposed in this paper. By using the Walsh domain waveform…”
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The Rate of CD4 T Cell Entry into the Lungs during Mycobacterium tuberculosis Infection Is Determined by Partial and Opposing Effects of Multiple Chemokine Receptors
Published in Infection and immunity (01-06-2019)“…The specific chemokine receptors utilized by Th1 cells to migrate into the lung during infection are unknown. We previously showed in mice that CXCR3 Th1 cells…”
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Unveiling Cancer-Related Metaplastic Cells in Both Helicobacter pylori Infection and Autoimmune Gastritis
Published in Gastroenterology (New York, N.Y. 1943) (03-09-2024)“…Gastric metaplasia may arise as a consequence of chronic inflammation and is associated with an increased risk of gastric cancer development. Although…”
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BRD4 Empowers Macrophages to Fight Helicobacter pylori
Published in Cellular and molecular gastroenterology and hepatology (01-01-2024)Get full text
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Single-cell analysis of peripheral CD8+ T cell responses in patients receiving checkpoint blockade immunotherapy for cancer
Published in Cancer Immunology, Immunotherapy (01-02-2023)“…Checkpoint blockade immunotherapy has become a first-line treatment option for cancer patients, with success in increasingly diverse cancer types. Still, many…”
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Limited Pulmonary Mucosal-Associated Invariant T Cell Accumulation and Activation during Mycobacterium tuberculosis Infection in Rhesus Macaques
Published in Infection and immunity (01-12-2018)“…Mucosal-associated invariant T cells (MAITs) are positioned in airways and may be important in the pulmonary cellular immune response against infection,…”
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IL13 Acts Directly on Gastric Epithelial Cells to Promote Metaplasia Development During Chronic Gastritis
Published in Cellular and molecular gastroenterology and hepatology (01-01-2022)“…It is well established that chronic inflammation promotes gastric cancer–associated metaplasia, but little is known regarding the mechanisms by which immune…”
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Synthesis and biological assessment of 3,7-dihydroxytropolones
Published in Organic & biomolecular chemistry (19-12-2017)“…3,7-Dihydroxytropolones (3,7-dHTs) are highly oxygenated troponoids that have been identified as lead compounds for several human diseases. To date,…”
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SOX9 Governs Gastric Mucous Neck Cell Identity and Is Required for Injury-Induced Metaplasia
Published in Cellular and molecular gastroenterology and hepatology (01-01-2023)“…Acute and chronic gastric injury induces alterations in differentiation within the corpus of the stomach called pyloric metaplasia. Pyloric metaplasia is…”
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Adaptive frequency domain control of PWM switched power line conditioner
Published in IEEE transactions on power electronics (01-10-1991)“…An adaptive frequency domain control algorithm for a pulse width modulation (PWM) switched active power line conditioner (PLC) is discussed. An active power…”
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