Search Results - "Hoft, Daniel F"

SARS-CoV-2 spike protein promotes IL-6 trans-signaling by activation of angiotensin II receptor signaling in epithelial cells by Patra, Tapas, Meyer, Keith, Geerling, Lizzie, Isbell, T Scott, Hoft, Daniel F, Brien, James, Pinto, Amelia K, Ray, Ratna B, Ray, Ranjit

“…Cytokine storm is suggested as one of the major pathological characteristics of SARS-CoV-2 infection, although the mechanism for initiation of a…”
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TLR8-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy by Li, Lingyun, Liu, Xia, Sanders, Katherine L., Edwards, James L., Ye, Jian, Si, Fusheng, Gao, Aiqin, Huang, Lan, Hsueh, Eddy C., Ford, David A., Hoft, Daniel F., Peng, Guangyong

“…Regulatory T (Treg) cells induce an immunosuppressive microenvironment that is a major obstacle for successful tumor immunotherapy. Dissecting the regulatory…”
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Regulatory T cells trigger effector T cell DNA damage and senescence caused by metabolic competition by Liu, Xia, Mo, Wei, Ye, Jian, Li, Lingyun, Zhang, Yanping, Hsueh, Eddy C., Hoft, Daniel F., Peng, Guangyong

“…Defining the suppressive mechanisms used by regulatory T (Treg) cells is critical for the development of effective strategies for treating tumors and chronic…”
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Tuberculosis vaccine development: goals, immunological design, and evaluation by Hoft, Daniel F, Prof

“…Summary A third of the world's population is infected with Mycobacterium tuberculosis , and 2 million people die from tuberculosis every year even though the…”
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Th17 Cells Are More Protective Than Th1 Cells Against the Intracellular Parasite Trypanosoma cruzi by Cai, Catherine W, Blase, Jennifer R, Zhang, Xiuli, Eickhoff, Christopher S, Hoft, Daniel F

“…Th17 cells are a subset of CD4+ T cells known to play a central role in the pathogenesis of many autoimmune diseases, as well as in the defense against some…”
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Impact of herpes zoster vaccination on incident dementia: A retrospective study in two patient cohorts by Scherrer, Jeffrey F, Salas, Joanne, Wiemken, Timothy L, Hoft, Daniel F, Jacobs, Christine, Morley, John E

“…Herpes zoster (HZ) infection increases dementia risk, but it is not known if herpes zoster vaccination is associated with lower risk for dementia. We…”
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Tumor Microenvironments Direct the Recruitment and Expansion of Human Th17 Cells by Su, Xinming, Ye, Jian, Hsueh, Eddy C, Zhang, Yanping, Hoft, Daniel F, Peng, Guangyong

“…Although Th17 cells play critical roles in the pathogenesis of many inflammatory and autoimmune diseases, their prevalence among tumor-infiltrating lymphocytes…”
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Polyclonal Mucosa-Associated Invariant T Cells Have Unique Innate Functions in Bacterial Infection by CHUA, Wei-Jen, TRUSCOTT, Steven M, EICKHOFF, Christopher S, BLAZEVIC, Azra, HOFT, Daniel F, HANSEN, Ted H

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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NK and NKT cells have distinct properties and functions in cancer by Liu, Xia, Li, Lingyun, Si, Fusheng, Huang, Lan, Zhao, Yangjing, Zhang, Chenchen, Hoft, Daniel F., Peng, Guangyong

“…Natural killer (NK) and natural killer T (NKT) cells are two important cell subsets of the innate immune system. NK and NKT cells share many phenotypes and…”
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BCG Vaccination Induces M. avium and M. abscessus Cross-Protective Immunity by Abate, Getahun, Hamzabegovic, Fahreta, Eickhoff, Christopher S, Hoft, Daniel F

“…Pulmonary non-tuberculous mycobacterial (NTM) infections particularly caused by complex (MAC) and (MAB) are becoming major health problems in the U.S. New…”
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Comparisons of the Humoral and Cellular Immune Responses Induced by Live Attenuated Influenza Vaccine and Inactivated Influenza Vaccine in Adults by Hoft, Daniel F, Lottenbach, Kathleen R, Blazevic, Azra, Turan, Aldin, Blevins, Tamara P, Pacatte, Thomas P, Yu, Yinyi, Mitchell, Michelle C, Hoft, Stella G, Belshe, Robert B

“…Both live attenuated influenza vaccines (LAIV) and inactivated influenza vaccines (IIV) induce protective immunity against influenza. There is evidence that…”
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Tristetraprolin inhibits macrophage IL-27-induced activation of antitumour cytotoxic T cell responses by Wang, Qinghong, Ning, Huan, Peng, Hui, Wei, Lin, Hou, Rong, Hoft, Daniel F., Liu, Jianguo

“…IFN-γ-producing cytotoxic T lymphocytes are essential for host defense against viral infection and cancer. Here we show that the RNA-binding tristetraprolin,…”
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Impact of BCG vaccination on the repertoire of human γδ T cell receptors by Xia, Mei, Blazevic, Azra, Fiore-Gartland, Andrew, Hoft, Daniel F

“…Tuberculosis (TB) caused by (Mtb) infection is a serious threat to human health. Vaccination with BCG prevents the development of the most severe forms of TB…”
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TLR8 signaling enhances tumor immunity by preventing tumor‐induced T‐cell senescence by Ye, Jian, Ma, Chunling, Hsueh, Eddy C, Dou, Jie, Mo, Wei, Liu, Shuai, Han, Bing, Huang, Yi, Zhang, Yanping, Varvares, Mark A, Hoft, Daniel F, Peng, Guangyong

“…Accumulating evidence suggests the immunosuppressive microenvironments created by malignant tumors represent a major obstacle for effective anti‐tumor…”
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Safety and immunogenicity of a thermostable ID93 + GLA-SE tuberculosis vaccine candidate in healthy adults by Sagawa, Zachary K., Goman, Cristina, Frevol, Aude, Blazevic, Azra, Tennant, Janice, Fisher, Bridget, Day, Tracey, Jackson, Stephen, Lemiale, Franck, Toussaint, Leon, Kalisz, Irene, Jiang, Joe, Ondrejcek, Lisa, Mohamath, Raodoh, Vergara, Julie, Lew, Alan, Beckmann, Anna Marie, Casper, Corey, Hoft, Daniel F., Fox, Christopher B.

“…Adjuvant-containing subunit vaccines represent a promising approach for protection against tuberculosis (TB), but current candidates require refrigerated…”
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Citrate Promotes Excessive Lipid Biosynthesis and Senescence in Tumor Cells for Tumor Therapy by Zhao, Yangjing, Liu, Xia, Si, Fusheng, Huang, Lan, Gao, Aiqin, Lin, Wenli, Hoft, Daniel F., Shao, Qixiang, Peng, Guangyong

“…Metabolic disorder is one of the hallmarks of cancers, and reprogramming of metabolism is becoming a novel strategy for cancer treatment. Citrate is a key…”
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Use of Leishmania major parasites expressing a recombinant Trypanosoma cruzi antigen as live vaccines against Chagas disease by Cai, Catherine W, O'Shea, Anne, Eickhoff, Christopher S, Guo, Hongjie, Lewis, Warren G, Beverley, Stephen M, Hoft, Daniel F

“…is the protozoan parasite causing Chagas disease, a Neglected Tropical Disease that affects 8 million people and causes 12,000 deaths per year, primarily…”
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Monocyte chemotactic protein–induced protein 1 controls allergic airway inflammation by suppressing IL-5–producing TH2 cells through the Notch/Gata3 pathway by Peng, Hui, Ning, Huan, Wang, Qinghong, Lu, Wenbao, Chang, Yingzi, Wang, Tony T., Lai, Jinping, Kolattukudy, Pappachan E., Hou, Rong, Hoft, Daniel F., Dykewicz, Mark S., Liu, Jianguo

“…Asthmatic and allergic inflammation is mediated by TH2 cytokines (IL-4, IL-5, and IL-13). Although we have learned much about how TH2 cells are differentiated,…”
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Distinct gene expression signatures comparing latent tuberculosis infection with different routes of Bacillus Calmette-Guérin vaccination by Silver, Richard F., Xia, Mei, Storer, Chad E., Jarvela, Jessica R., Moyer, Michelle C., Blazevic, Azra, Stoeckel, David A., Rakey, Erin K., Tennant, Jan M., Goll, Johannes B., Head, Richard D., Hoft, Daniel F.

“…Tuberculosis remains an international health threat partly because of limited protection from pulmonary tuberculosis provided by standard intradermal…”
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Pilot studies of a human BCG challenge model by Blazevic, Azra, Xia, Mei, Turan, Aldin, Tennant, Janice, Hoft, Daniel F., M.D., Ph.D

“…Abstract Despite the great effort to develop an effective vaccine against tuberculosis (TB) there is currently no reliable and safe human challenge model that…”
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