Search Results - "Hofstetter, Willy"

Rapid evaluation of bioactive Ti-based surfaces using an in vitro titration method by Zhao, Weitian, Michalik, David, Ferguson, Stephen, Hofstetter, Willy, Lemaître, Jacques, von Rechenberg, Brigitte, Bowen, Paul

“…The prediction of implant behavior in vivo by the use of easy-to-perform in vitro methods is of great interest in biomaterials research. Simulated body fluids…”
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Extracellular Iron is a Modulator of the Differentiation of Osteoclast Lineage Cells by Xie, Wenjie, Lorenz, Sebastian, Dolder, Silvia, Hofstetter, Willy

“…Osteoclasts originate from the hematopoietic stem cell and share a differentiation pathway with the cells of the monocyte/macrophage lineages. Development and…”
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Transforming growth factor beta signaling is essential for the autonomous formation of cartilage-like tissue by expanded chondrocytes by Tekari, Adel, Luginbuehl, Reto, Hofstetter, Willy, Egli, Rainer J

“…Cartilage is a tissue with limited self-healing potential. Hence, cartilage defects require surgical attention to prevent or postpone the development of…”
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TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance by Weber, Benjamin, Schuster, Steffen, Zysset, Daniel, Rihs, Silvia, Dickgreber, Nina, Schürch, Christian, Riether, Carsten, Siegrist, Mark, Schneider, Christoph, Pawelski, Helga, Gurzeler, Ursina, Ziltener, Pascal, Genitsch, Vera, Tacchini-Cottier, Fabienne, Ochsenbein, Adrian, Hofstetter, Willy, Kopf, Manfred, Kaufmann, Thomas, Oxenius, Annette, Reith, Walter, Saurer, Leslie, Mueller, Christoph

“…Triggering receptor expressed on myeloid cells-1 (TREM-1) is a potent amplifier of pro-inflammatory innate immune reactions. While TREM-1-amplified responses…”
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Impact of pore size on the vascularization and osseointegration of ceramic bone substitutes in vivo by Klenke, Frank M., Liu, Yuelian, Yuan, Huipin, Hunziker, Ernst B., Siebenrock, Klaus A., Hofstetter, Willy

“…The repair of bone defects with biomaterials depends on a sufficient vascularization of the implantation site. We analyzed the effect of pore size on the…”
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Chondrocytes expressing intracellular collagen type II enter the cell cycle and co-express collagen type I in monolayer culture by Tekari, Adel, Luginbuehl, Reto, Hofstetter, Willy, Egli, Rainer J.

“…ABSTRACT For autologous chondrocyte transplantation, articular chondrocytes are harvested from cartilage tissue and expanded in vitro in monolayer culture. We…”
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Blockade of the hedgehog pathway inhibits osteophyte formation in arthritis by Ruiz-Heiland, Gisela, Horn, Angelika, Zerr, Pawel, Hofstetter, Willy, Baum, Wolfgang, Stock, Michael, Distler, Jörg H, Nimmerjahn, Falk, Schett, Georg, Zwerina, Jochen

“…Osteophyte formation is a common phenomenon in arthritis. Bone formation by endochondral ossification is considered a key pathophysiological process in the…”
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Bisphosphonates do not affect healing of a critical-size defect in estrogen-deficient mice by Strunz, Franziska, Gentil-Perret, Saskia, Siegrist, Mark, Bohner, Marc, Saulacic, Nikola, Hofstetter, Willy

“…Bisphosphonates (BP) are anti-resorptive drugs that are widely used to prevent bone loss in osteoporosis. Since inhibition of bone resorption will cause a…”
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Association between cam‐type deformities and magnetic resonance imaging–detected structural hip damage: A cross‐sectional study in young men by Reichenbach, Stephan, Leunig, Michael, Werlen, Stefan, Nüesch, Eveline, Pfirrmann, Christian W., Bonel, Harald, Odermatt, Alex, Hofstetter, Willy, Ganz, Reinhold, Jüni, Peter

“…Objective Femoroacetabular impingement may be a risk factor for hip osteoarthritis in men. An underlying hip deformity of the cam type is common in…”
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Effects of local application of alendronate on early healing of extraction socket in dogs by Saulacic, Nikola, Muñoz, Fernando, Kobayashi, Eizaburo, Chappuis, Vivianne, Gonzáles-Cantalapiedra, Antonio, Hofstetter, Willy

“…Objective The aim of the present study was to assess the effects of alendronate (ALN) on bone remodeling following tooth extraction in a dog model. Material…”
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The Allelic Variant A391T of Metal Ion Transporter ZIP8 (SLC39A8) Leads to Hypotension and Enhanced Insulin Resistance by Verouti, Sophia N., Pujol-Giménez, Jonai, Bermudez-Lekerika, Paola, Scherler, Laeticia, Bhardwaj, Rajesh, Thomas, Aurélien, Lenglet, Sébastien, Siegrist, Mark, Hofstetter, Willy, Fuster, Daniel G., Hediger, Matthias A., Escher, Geneviève, Vogt, Bruno

“…The metal ion transporter ZIP8 (SLC39A8) mediates cellular uptake of vital divalent metal ions. Genome-wide association studies (GWAS) showed that the…”
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Sodium-dependent phosphate transporters in osteoclast differentiation and function by Albano, Giuseppe, Moor, Matthias, Dolder, Silvia, Siegrist, Mark, Wagner, Carsten A, Biber, Jürg, Hernando, Nati, Hofstetter, Willy, Bonny, Olivier, Fuster, Daniel G

“…Osteoclasts are multinucleated bone degrading cells. Phosphate is an important constituent of mineralized bone and released in significant quantities during…”
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Comparison of two protocols of periosteal distraction osteogenesis in a rabbit calvaria model by Saulacic, Nikola, Nakahara, Ken, Iizuka, Tateyuki, Haga-Tsujimura, Maiko, Hofstetter, Willy, Scolozzi, Paolo

“…The regenerative pathways during periosteal distraction osteogenesis may be influenced by the local environment composed by cells, growth factors, nutrition…”
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Repair of a critical size defect in osteoporotic mice by Strunz, Franziska, Siegrist, Mark, Saulacic, Nikola, Bohner, Marc, Hofstetter, Willy

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Application of Cytokines of the Bone Morphogenetic Protein (BMP) Family in Spinal Fusion - Effects on the Bone, Intervertebral Disc and Mesenchymal Stromal Cells by May, Rahel Deborah, Frauchiger, Daniela Angelika, Albers, Christoph Emmanuel, Tekari, Adel, Benneker, Lorin Michael, Klenke, Frank Michael, Hofstetter, Willy, Gantenbein, Benjamin

“…Low back pain is a prevalent socio-economic burden and is often associated with damaged or degenerated intervertebral discs (IVDs). When conservative therapy…”
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Osteosynthesis of partial rib osteotomy in a miniature pig model using human standard-sized magnesium plate/screw systems: effect of cyclic deformation on implant integrity and bone healing by Schaller, Benoit, MD, DMD, Saulacic, Nikola, DDS, PhD, Beck, Stefan, PhD, Imwinkelried, Thomas, PhD, Liu, Edwin Wei Yang, PhD, Nakahara, Ken, DDS, PhD, Hofstetter, Willy, PhD, Iizuka, Tateyuki, MD, DDS, PhD

“…Abstract Magnesium alloys are candidates for resorbable material in bone fixation. However, the degradation and performance of osteosynthesis plate/screw…”
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Influence of defective bone marrow osteogenesis on fracture repair in an experimental model of senile osteoporosis by Egermann, Marcus, Heil, Petra, Tami, Andrea, Ito, Keita, Janicki, Patricia, Von Rechenberg, Brigitte, Hofstetter, Willy, Richards, Peter J.

“…Bone marrow osteogenesis in senile osteoporotic bone is impaired and, as such, may have significant implications on the successful outcome of fracture repair…”
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Noggin as a regulator of bone remodelling by Safari, Fatemeh, Siegrist, Mark, Dolder, Silvia, Hartmann, Eliza, Klenke, Frank, Hofstetter, Willy

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The inositol phosphatase SHIP1 regulates skeletal development by Safari, Fatemeh, Yeoh, Jeremy, Bringardner, Margaux, Siegrist, Mark, Dolder, Silvia, Strunz, Franziska, Hofstetter, Willy, Krebs, Philippe

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Bisphosphonates reduce biomaterial turnover in healing of critical-size rat femoral defects by Hauser, Michel, Siegrist, Mark, Denzer, Alain, Saulacic, Nikola, Grosjean, Joël, Bohner, Marc, Hofstetter, Willy

“…Treatment of osteoporotic patients with bisphosphonates (BPs) preserves bone mass and microarchitecture. The high prescription rate of the drugs brings about…”
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