Neuroendocrine cells are present in the domestic fowl ovary

Neuroendocrine cells are present in the domestic fowl ovary

Neuroendocrine cells are present in virtually all organs of the vertebrate body; however, it is yet uncertain whether they exist in the ovaries. Previous reports of ovarian neurons and neuron‐like cells in mammals and birds might have resulted from misidentification. The aim of the present work was...

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Bibliographic Details
Published in:Journal of anatomy Vol. 222; no. 2; pp. 170 - 177
Main Authors: Hofmann, Pablo G., Báez Saldaña, Armida, Fortoul Van Der Goes, Teresa, González del Pliego, Margarita, Gutiérrez Ospina, Gabriel
Format: Journal Article
Language:English
Published: England Wiley Subscription Services, Inc 01-02-2013
Blackwell Science Inc
Subjects:
Animals
Biomarkers - analysis
birds
catecholamines
Chickens
chromagranin‐A
Female
Fluorescent Antibody Technique
neuroendocrine cell
Neuroendocrine Cells - cytology
Neuroendocrine Cells - immunology
Neuroendocrine Cells - ultrastructure
Neurofilament Proteins - immunology
Neurons
Original
Ovary - cytology
Ovary - immunology
serotonin
synaptophysin
Synaptophysin - immunology
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Summary:Neuroendocrine cells are present in virtually all organs of the vertebrate body; however, it is yet uncertain whether they exist in the ovaries. Previous reports of ovarian neurons and neuron‐like cells in mammals and birds might have resulted from misidentification. The aim of the present work was to determine the identity of neuron‐like cells in immature ovaries of the domestic fowl. Cells immunoreactive to neurofilaments, synaptophysin, and chromogranin‐A, with small, dense‐core secretory granules, were consistently observed throughout the sub‐cortical ovarian medulla and cortical interfollicular stroma. These cells also displayed immunoreactivity for tyrosine, tryptophan and dopamine β‐hydroxylases, as well as to aromatic L‐DOPA decarboxylase, implying their ability to synthesize both catecholamines and indolamines. Our results support the argument that the ovarian cells previously reported as neuron‐like in birds, are neuroendocrine cells.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0021-8782
1469-7580
DOI:10.1111/joa.12002