Search Results - "Hofmann, Kay"

Bacterial DUBs: deubiquitination beyond the seven classes by Hermanns, Thomas, Hofmann, Kay

“…Protein ubiquitination is a posttranslational modification that regulates many aspects of cellular life, including proteostasis, vesicular trafficking, DNA…”
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Identifying Firm Capabilities as Drivers of Environmental Management and Sustainability Practices - Evidence from Small and Medium-Sized Manufacturers by Hofmann, Kay H., Theyel, Gregory, Wood, Craig H.

“…ABSTRACT Firms increasingly need to consider environmental issues as a result of stricter governmental regulation and due to growing pressures from a broad…”
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MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes by Abdul Rehman, Syed Arif, Kristariyanto, Yosua Adi, Choi, Soo-Youn, Nkosi, Pedro Junior, Weidlich, Simone, Labib, Karim, Hofmann, Kay, Kulathu, Yogesh

“…Deubiquitinating enzymes (DUBs) remove ubiquitin (Ub) from Ub-conjugated substrates to regulate the functional outcome of ubiquitylation. Here we report the…”
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A widely distributed family of eukaryotic and bacterial deubiquitinases related to herpesviral large tegument proteins by Erven, Ilka, Abraham, Elena, Hermanns, Thomas, Baumann, Ulrich, Hofmann, Kay

“…Distinct families of eukaryotic deubiquitinases (DUBs) are regulators of ubiquitin signaling. Here, we report on the presence of an additional DUB class…”
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A family of unconventional deubiquitinases with modular chain specificity determinants by Hermanns, Thomas, Pichlo, Christian, Woiwode, Ilka, Klopffleisch, Karsten, Witting, Katharina F., Ovaa, Huib, Baumann, Ulrich, Hofmann, Kay

“…Deubiquitinating enzymes (DUBs) regulate ubiquitin signaling by trimming ubiquitin chains or removing ubiquitin from modified substrates. Similar activities…”
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Talent and publicity as determinants of superstar incomes: empirical evidence from the motion picture industry by Hofmann, Kay H., Opitz, Christian

“…By drawing on the two prevailing economic stardom theories, the paper investigates the sources of superstardom in the US movie industry. For the econometric…”
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A structural basis for the diverse linkage specificities within the ZUFSP deubiquitinase family by Hermanns, Thomas, Pichlo, Christian, Baumann, Ulrich, Hofmann, Kay

“…Eukaryotic deubiquitinases are important regulators of ubiquitin signaling and can be subdivided into several structurally distinct classes. The ZUFSP family,…”
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ZFAND1 Recruits p97 and the 26S Proteasome to Promote the Clearance of Arsenite-Induced Stress Granules by Turakhiya, Ankit, Meyer, Susanne R., Marincola, Gabriella, Böhm, Stefanie, Vanselow, Jens T., Schlosser, Andreas, Hofmann, Kay, Buchberger, Alexander

“…Stress granules (SGs) are cytoplasmic assemblies of mRNPs stalled in translation initiation. They are induced by various stress conditions, including exposure…”
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Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery by Fumagalli, Fiorenza, Noack, Julia, Bergmann, Timothy J., Cebollero, Eduardo, Pisoni, Giorgia Brambilla, Fasana, Elisa, Fregno, Ilaria, Galli, Carmela, Loi, Marisa, Soldà, Tatiana, D’Antuono, Rocco, Raimondi, Andrea, Jung, Martin, Melnyk, Armin, Schorr, Stefan, Schreiber, Anne, Simonelli, Luca, Varani, Luca, Wilson-Zbinden, Caroline, Zerbe, Oliver, Hofmann, Kay, Peter, Matthias, Quadroni, Manfredo, Zimmermann, Richard, Molinari, Maurizio

“…The endoplasmic reticulum (ER) is a site of protein biogenesis in eukaryotic cells. Perturbing ER homeostasis activates stress programs collectively called the…”
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Proximity-dependent protein (de)stabilization: screening the human ORFeome for protein degraders and stabilizers by Hermanns, Thomas, Hofmann, Kay

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Manufacturing location decisions and organizational agility by Theyel, Gregory, Hofmann, Kay H

“…Purpose This paper aims to investigate the strategic consequences of manufacturing location decisions, with a focus on understanding the link between…”
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Television serials as career stepping stones: An empirical analysis of employment paths of professional actors by Hofmann, Kay H

“…Guided by cultural labor economics, the paper analyzes the career paths of former actors from popular television soap operas, and addresses in particular, if…”
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Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy by Kraft, Claudine, Kijanska, Monika, Kalie, Eyal, Siergiejuk, Edyta, Lee, Sung Sik, Semplicio, Giuseppe, Stoffel, Ingrid, Brezovich, Andrea, Verma, Mayanka, Hansmann, Isabella, Ammerer, Gustav, Hofmann, Kay, Tooze, Sharon, Peter, Matthias

“…Autophagy is an intracellular trafficking pathway sequestering cytoplasm and delivering excess and damaged cargo to the vacuole for degradation. The Atg1/ULK1…”
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Identification of a novel cell death-inducing domain reveals that fungal amyloid-controlled programmed cell death is related to necroptosis by Daskalov, Asen, Habenstein, Birgit, Sabaté, Raimon, Berbon, Mélanie, Martinez, Denis, Chaignepain, Stéphane, Coulary-Salin, Bénédicte, Hofmann, Kay, Loquet, Antoine, Saupe, Sven J.

“…Recent findings have revealed the role of prion-like mechanisms in the control of host defense and programmed cell death cascades. In fungi, HET-S, a cell…”
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Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links by Räschle, Markus, Smeenk, Godelieve, Hansen, Rebecca K., Temu, Tikira, Oka, Yasuyoshi, Hein, Marco Y., Nagaraj, Nagarjuna, Long, David T., Walter, Johannes C., Hofmann, Kay, Storchova, Zuzana, Cox, Jürgen, Bekker-Jensen, Simon, Mailand, Niels, Mann, Matthias

“…Uncrossing covalently linked DNA strands DNA interstrand cross-links (ICLs) covalently link the two strands of the double helix. ICL mutations are difficult to…”
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A short conserved motif in ALYREF directs cap- and EJC-dependent assembly of export complexes on spliced mRNAs by Gromadzka, Agnieszka M, Steckelberg, Anna-Lena, Singh, Kusum K, Hofmann, Kay, Gehring, Niels H

“…The export of messenger RNAs (mRNAs) is the final of several nuclear posttranscriptional steps of gene expression. The formation of export-competent mRNPs…”
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Arkadia/RNF111 is a SUMO-targeted ubiquitin ligase with preference for substrates marked with SUMO1-capped SUMO2/3 chain by Sriramachandran, Annie M., Meyer-Teschendorf, Katrin, Pabst, Stefan, Ulrich, Helle D., Gehring, Niels H., Hofmann, Kay, Praefcke, Gerrit J. K., Dohmen, R. Jürgen

“…Modification with SUMO regulates many eukaryotic proteins. Down-regulation of sumoylated forms of proteins involves either their desumoylation, and hence…”
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Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus by Bartenschlager, Ralf, Tschopp, Jürg, Meylan, Etienne, Hofmann, Kay, Moradpour, Darius, Binder, Marco, Curran, Joseph

“…Antiviral immunity against a pathogen is mounted upon recognition by the host of virally associated structures. One of these viral 'signatures',…”
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Identification and characterization of diverse OTU deubiquitinases in bacteria by Schubert, Alexander F, Nguyen, Justine V, Franklin, Tyler G, Geurink, Paul P, Roberts, Cameron G, Sanderson, Daniel J, Miller, Lauren N, Ovaa, Huib, Hofmann, Kay, Pruneda, Jonathan N, Komander, David

“…Manipulation of host ubiquitin signaling is becoming an increasingly apparent evolutionary strategy among bacterial and viral pathogens. By removing host…”
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Bacterial ribosome collision sensing by a MutS DNA repair ATPase paralogue by Cerullo, Federico, Filbeck, Sebastian, Patil, Pratik Rajendra, Hung, Hao-Chih, Xu, Haifei, Vornberger, Julia, Hofer, Florian W., Schmitt, Jaro, Kramer, Guenter, Bukau, Bernd, Hofmann, Kay, Pfeffer, Stefan, Joazeiro, Claudio A. P.

“…Ribosome stalling during translation is detrimental to cellular fitness, but how this is sensed and elicits recycling of ribosomal subunits and quality control…”
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