Search Results - "Hofkens, Wouter"

Liposomal targeting of prednisolone phosphate to synovial lining macrophages during experimental arthritis inhibits M1 activation but does not favor M2 differentiation by Hofkens, Wouter, Schelbergen, Rik, Storm, Gert, van den Berg, Wim B, van Lent, Peter L

“…To determine the effects of liposomal targeting of prednisolone phosphate (Lip-PLP) to synovial lining macrophages on M1 and M2 polarization in vitro and…”
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Optimizing the therapeutic index of liposomal glucocorticoids in experimental arthritis by van den Hoven, Jolanda M., Hofkens, Wouter, Wauben, Marca H.M., Wagenaar-Hilbers, Josee P.A., Beijnen, Jos H., Nuijen, Bastiaan, Metselaar, Josbert M., Storm, Gert

“…Small-sized (less than 150 nm) long-circulating liposomes (LCL) may be useful as drug-targeting vehicles for anti-inflammatory agents in arthritis, since they…”
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Intravenously delivered glucocorticoid liposomes inhibit osteoclast activity and bone erosion in murine antigen-induced arthritis by Hofkens, Wouter, Grevers, Lilyanne C., Walgreen, Birgitte, de Vries, Teun J., Leenen, Pieter J.M., Everts, Vincent, Storm, Gert, van den Berg, Wim B., van Lent, Peter L.

“…The objective of this study was to determine the effect of systemic delivery of prednisolone phosphate (PLP) encapsulated within long circulating ‘stealth’…”
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Safety of glucocorticoids can be improved by lower yet still effective dosages of liposomal steroid formulations in murine antigen-induced arthritis: Comparison of prednisolone with budesonide by Hofkens, Wouter, van den Hoven, Jolanda M., Pesman, Gerard J., Nabbe, Karin C., Sweep, Fred C., Storm, Gert, van den Berg, Wim B., van Lent, Peter L.

“…The goal of this study was to compare the effects of liposomal and free glucocorticoid formulations on joint inflammation and activity of the…”
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Selectively induced death of macrophages in the synovial lining of murine knee joints using 10 B-liposomes and boron neutron capture synovectomy by van Lent, Peter L. E. M., Krijger, Gerard C., Hofkens, Wouter, Nievaart, Victor A., Sloetjes, Annet W., Moss, Ray L., Koning, Gerben A., van den Berg, Wim B.

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Selectively induced death of macrophages in the synovial lining of murine knee joints using 10B-liposomes and boron neutron capture synovectomy by van Lent, Peter L E M, Krijger, Gerard C, Hofkens, Wouter, Nievaart, Victor A, Sloetjes, Annet W, Moss, Ray L, Koning, Gerben A, van den Berg, Wim B

“…To investigate whether macrophages in the synovial lining can be selectively eliminated by local administration of an improved boron-10 ((10)B) containing…”
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Selectively induced death of macrophages in the synovial lining of murine knee joints using 10B-liposomes and boron neutron capture synovectomy by van Lent, Peter L. E. M., Krijger, Gerard C., Hofkens, Wouter, Nievaart, Victor A., Sloetjes, Annet W., Moss, Ray L., Koning, Gerben A., van den Berg, Wim B.

“…Objective: To investigate whether macrophages in the synovial lining can be selectively eliminated by local administration of an improved boron-10 (10B)…”
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