Search Results - "Hofhuis, F M A"

Chronic overproduction of islet amyloid polypeptide/amylin in transgenic mice : lysosomal localization of human islet amyloid polypeptide and lack of marked hyperglycaemia or hyperinsulinaemia by HÖPPENER, J. W. M, VERBEEK, J. S, JANSZ, H. S, MORRIS, J. F, CLARK, A, CAPEL, P. J. A, LIPS, C. J. M, DE KONING, E. J. P, OOSTERWIJK, C, VAN HULST, K. L, VISSER-VERNOOY, H. J, HOFHUIS, F. M. A, VAN GAALEN, S, BERENDS, M. J. H, HACKENG, W. H. L

“…Type 2 (non-insulin-dependent) diabetes mellitus is characterised by hyperglycaemia, peripheral insulin resistance, impaired insulin secretion and pancreatic…”
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Increased susceptibility to ultraviolet-B and carcinogens of mice lacking the DNA excision repair gene XPA by Vries, Annemieke de, van Oostrom, Conny Th. M, Hofhuis, Frans M. A, Dortant, Paul M, Berg, Rob J. W, Gruijl, Frank R. de, Wester, Piet W, van Kreijl, Coen F, Capel, Peter J. A, Steeg, Harry van, Verbeek, Sjef J

“…Xeroderma pigmentosum patients with a defect in the nucleotide-excision repair gene XPA are characterized by, for example, a > 1,000-fold higher risk of…”
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Killed Listeria monocytogenes vaccine becomes protective on addition of polyanions by MEER, C. VAN DER, HOFHUIS, F. M. A, WILLERS, J. M. N

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FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection by Ioan-Facsinay, A, de Kimpe, S J, Hellwig, S M M, van Lent, P L, Hofhuis, F M A, van Ojik, H H, Sedlik, C, da Silveira, S A, Gerber, J, de Jong, Y F, Roozendaal, R, Aarden, L A, van den Berg, W B, Saito, T, Mosser, D, Amigorena, S, Izui, S, van Ommen, G J B, van Vugt, M, van de Winkel, J G J, Verbeek, J S

“…The high-affinity receptor for IgG, FcgammaRI, shares its capacity to bind IgG2a immune complexes (IgG2a-IC) with the low-affinity receptor FcgammaRIII and…”
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Human Immunoglobulin A Receptor (FcαRI, CD89) Function in Transgenic Mice Requires Both FcR γ Chain and CR3 (CD11b/CD18) by van Egmond, Marjolein, van Vuuren, A.J. Hanneke, Morton, H. Craig, van Spriel, Annemiek B., Shen, Li, Hofhuis, Frans M.A., Saito, Takashi, Mayadas, Tanya N., Verbeek, J. Sjef, van de Winkel, Jan G.J.

“…Even though more immunoglobulin A (IgA) is produced in humans than all other isotypes combined, relatively little is known about receptors that bind the Fc…”
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Immunoadjuvant activity of a liposomal IL-6 formulation by Duits, A J, van Puijenbroek, A, Vermeulen, H, Hofhuis, F M, van de Winkel, J G, Capel, P J

“…The adjuvant effect of interleukin 6 (IL-6) entrapped in liposomes was evaluated using a 65 kDa heat shock protein as a model antigen. The secondary humoral…”
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Induction of active immunological hypo/non-responsiveness to C5 in adult C5-deficient DBA/2 mice by VAN DEN BERG, C. W, HOFHUIS, F. M. A, RADEMAKER, P. M, VAN DIJK, H

“…Injection of C5-sufficient BALB/c serum rendered DBA/2 mice (C5-deficient) immunologically hypo- or non-responsive to C5. This was indicated by C5-elimination…”
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Synergistic action of human recombinant tumor necrosis factor with endotoxins or nontoxic poly A:U against solid Meth A tumors in mice by BLOKSMA, N, HOFHUIS, F. M. A

“…Antitumor effects of i.v. injected human recombinant tumor necrosis factor (rTNF) against solid Meth A tumors in mice appeared to be critically dependent on…”
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Endotoxin-induced antitumor activity in the mouse is highly potentiated by muramyl dipeptide by Bloksma, N, Hofhuis, F M, Willers, J M

“…The ability of aqueous solutions of various endotoxin preparations, muramyl dipeptide (MDP) and combinations of endotoxin and MDP, to induce necrosis and…”
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Induction of auto-antibody formation in C3H/HeJ mice by cobra venom factor by Bloembergen, P, Hol, C, Hofhuis, F M, van Dijk, H

“…Recently, we demonstrated that lipopolysaccharide (LPS)-hyporesponsive C3H/HeJ mice show a very high background number of splenic antibody-forming cells with…”
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C3- and T-cell-dependent adjuvant activity of in vivo formed immune complexes by VAN DEN BERG, C. W, HAZENBERG, M. A. J, HOFHUIS, F. M. A, VAN ROOYEN, S. M, VAN DIJK, H

“…The effects of polyclonal antibodies to mouse serum components on the primary humoral immune response of mice in vivo were studied. It was observed that rabbit…”
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Muramyl dipeptide analogues as potentiators of the antitumor action of endotoxin by BLOKSMA, N, HOFHUIS, F. M. A, WILLERS, J. M. N

“…The potentiation of endotoxin-induced necrosis and regression of solid syngeneic Meth A tumors in mice previously observed following administration of…”
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Antitumour activity of endotoxin, concanavalin A and poly I: C and their ability to elicit tumour necrosis factor, cytostatics factors, and interferon in vivo by BLOKSMA, N, KUPER, C. F, HOFHUIS, F. M. A, BENAISSA-TROUW, B, WILLERS, J. M. N

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Relation between splenic antibody formation and serum antibody levels to sheep erythrocytes as studied at the level of individual mice by Hol, C, Hofhuis, F M, van Dijk, H

“…The relation between splenic antibody formation and serum antibody levels after intraperitoneal immunization of mice with sheep erythrocytes was studied in…”
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C5 does not play a major role in the immune response of mice to SRBC in vivo by van den Berg, C W, van Horssen, P J, Hofhuis, F M, Aerts, P C, van Dijk, H

“…The role of complement component C5 in the immune response of mice to sheep red blood cells (SRBC) was investigated. Congenic C5-sufficient and C5-deficient…”
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Muramyl dipeptide is a powerful potentiator of the antitumor action of various tumor-necrotizing agents by BLOKSMA, N, HOFHUIS, F. M. A, WILLERS, J. M. N

“…The previously observed potentiation of necrosis and regression of solid immunogenic Meth A sarcoma transplants in mice after IV administration of endotoxin by…”
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Prolongation of acquired cellular resistance to Listeria monocytogenes by Willers, J M, Hofhuis, F M, Van der Meer, C

“…Intracutaneous immunization of mice with 10 5 or 10 6 viable listeria resulted in acquired cellular resistance (ACR) of short duration (7 days) and in…”
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Role of vasoactive amines in the antitumor activity of endotoxin by Bloksma, N, Kuper, C F, Hofhuis, F M, Willers, J M

“…To estimate a possible role of vasoamines in the antitumor action of endotoxin, effects of isoproterenol, serotonin and adrenaline on subcutaneously…”
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Regulation of the immune response by macrophages by Willers, J M, Bloksma, N, van der Meer, C, Snippe, H, van Dijk, H, de Reuver, M J, Hofhuis, F M

“…Regulation of the immune response by macrophages was studied with cellular resistance to Listeria monocytogenes as parameter. The use of agents which suppress…”
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Induction of acquired cellular resistance in mice with viable and macrophage-processed Listeria monocytogenes by van der Meer, C, Hofhuis, F M, Willers, J M

“…Intracutaneous immunization of mice with 10(5) or 10(6) viable listeria resulted in acquired cellular resistance (ACR) of short duration (7 days). The period…”
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