Search Results - "Hoffmann, Toni"

Single molecule force spectroscopy using polyproteins by Hoffmann, Toni, Dougan, Lorna

“…In recent years single molecule force spectroscopy has emerged as a powerful new tool to explore the mechanical stability and folding pathways of individual…”
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Rapid and Robust Polyprotein Production Facilitates Single-Molecule Mechanical Characterization of β‑Barrel Assembly Machinery Polypeptide Transport Associated Domains by Hoffmann, Toni, Tych, Katarzyna M, Crosskey, Thomas, Schiffrin, Bob, Brockwell, David J, Dougan, Lorna

“…Single-molecule force spectroscopy by atomic force microscopy exploits the use of multimeric protein constructs, namely, polyproteins, to decrease the impact…”
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Towards design principles for determining the mechanical stability of proteins by Hoffmann, Toni, Tych, Katarzyna M, Hughes, Megan L, Brockwell, David J, Dougan, Lorna

“…The successful integration of proteins into bionanomaterials with specific and desired functions requires an accurate understanding of their material…”
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Single-Molecule Force Spectroscopy Identifies a Small Cold Shock Protein as Being Mechanically Robust by Hoffmann, Toni, Tych, Katarzyna M, Brockwell, David J, Dougan, Lorna

“…Single-molecule force spectroscopy has emerged as a powerful approach to examine the stability and dynamics of single proteins. We have completed force…”
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Differential Effects of Hydrophobic Core Packing Residues for Thermodynamic and Mechanical Stability of a Hyperthermophilic Protein by Tych, Katarzyna M, Batchelor, Matthew, Hoffmann, Toni, Wilson, Michael C, Hughes, Megan L, Paci, Emanuele, Brockwell, David J, Dougan, Lorna

“…Proteins from organisms that have adapted to environmental extremes provide attractive systems to explore and determine the origins of protein stability…”
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Tuning protein mechanics through an ionic cluster graft from an extremophilic protein by Tych, Katarzyna M, Batchelor, Matthew, Hoffmann, Toni, Wilson, Michael C, Paci, Emanuele, Brockwell, David J, Dougan, Lorna

“…Proteins from extremophilic organisms provide excellent model systems to determine the role of non-covalent interactions in defining protein stability and…”
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Structure−function studies of an engineered scaffold protein derived from Stefin A. II: Development and applications of the SQT variant by Stadler, Lukas Kurt Josef, Hoffmann, Toni, Tomlinson, Darren Charles, Song, Qifeng, Lee, Tracy, Busby, Michael, Nyathi, Yvonne, Gendra, Elisenda, Tiede, Christian, Flanagan, Keith, Cockell, Simon J., Wipat, Anil, Harwood, Colin, Wagner, Simon D., Knowles, Margaret A., Davis, Jason J., Keegan, Neil, Ko Ferrigno, Paul

“…Constrained binding peptides (peptide aptamers) may serve as tools to explore protein conformations and disrupt protein−protein interactions. The quality of…”
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Life in extreme environments: single molecule force spectroscopy as a tool to explore proteins from extremophilic organisms by Tych, Katarzyna M, Hoffmann, Toni, Batchelor, Matthew, Hughes, Megan L, Kendrick, Katherine E, Walsh, Danielle L, Wilson, Michael, Brockwell, David J, Dougan, Lorna

“…Extremophiles are organisms which survive and thrive in extreme environments. The proteins from extremophilic single-celled organisms have received…”
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Structure-function studies of an engineered scaffold protein derived from stefin A. I: Development of the SQM variant by Hoffmann, Toni, Stadler, Lukas Kurt Josef, Busby, Michael, Song, Qifeng, Buxton, Anthony T., Wagner, Simon D., Davis, Jason J., Ko Ferrigno, Paul

“…Non-antibody scaffold proteins are used for a range of applications, especially the assessment of protein–protein interactions within human cells. The search…”
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Paralogs of genes encoding metal resistance proteins in Cupriavidus metallidurans strain CH34 by Nies, Dietrich H, Rehbein, Grit, Hoffmann, Toni, Baumann, Cindy, Grosse, Cornelia

“…Cupriavidus (Wautersia, Ralstonia, Alcaligenes) metallidurans strain CH34is a well-studied example of a metal-resistant proteobacterium. Genome sequence…”
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Identification of a regulatory pathway that controls the heavy-metal resistance system Czc via promoter czcNp in Ralstonia metallidurans by GROSSE, Cornelia, ANTON, Andreas, HOFFMANN, Toni, FRANKE, Sylvia, SCHLEUDER, Grit, NIES, Dietrich H

“…The CzcCBA cation-proton-antiporter is the most complicated and efficient heavy-metal resistance system known today and is essential for survival of Ralstonia…”
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First step towards a quantitative model describing Czc-mediated heavy metal resistance in Ralstonia metallidurans by Legatzki, Antje, Franke, Sylvia, Lucke, Susann, Hoffmann, Toni, Anton, Andreas, Neumann, Dieter, Nies, Dietrich H

“…Quantitative models were derived to explain heavy metal resistance in Ralstonia metallidurans. A deltaczcA deletion of the gene for the central component of…”
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First step towards a quantitative model describing Czc-mediated heavy metal resistance in Ralstonia metallidurans: Special Issue on Metal-Microbe Interactions by LEGATZKI, Antje, FRANKE, Sylvia, LUCKE, Susann, HOFFMANN, Toni, ANTON, Andreas, NEUMANN, Dieter, NIES, Dietrich H

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