Search Results - "Hoffmann, Pavel"

Prevention of cardiac dysfunction during adjuvant breast cancer therapy (PRADA): a 2 × 2 factorial, randomized, placebo-controlled, double-blind clinical trial of candesartan and metoprolol by Gulati, Geeta, Heck, Siri Lagethon, Ree, Anne Hansen, Hoffmann, Pavel, Schulz-Menger, Jeanette, Fagerland, Morten W, Gravdehaug, Berit, von Knobelsdorff-Brenkenhoff, Florian, Bratland, Åse, Storås, Tryggve H, Hagve, Tor-Arne, Røsjø, Helge, Steine, Kjetil, Geisler, Jürgen, Omland, Torbjørn

“…Contemporary adjuvant treatment for early breast cancer is associated with improved survival but at the cost of increased risk of cardiotoxicity and cardiac…”
Get full text

OCT or Angiography Guidance for PCI in Complex Bifurcation Lesions by Holm, Niels R., Andreasen, Lene N., Neghabat, Omeed, Laanmets, Peep, Kumsars, Indulis, Bennett, Johan, Olsen, Niels T., Odenstedt, Jacob, Hoffmann, Pavel, Dens, Jo, Chowdhary, Saqib, O’Kane, Peter, Bülow Rasmussen, Søren-Haldur, Heigert, Matthias, Havndrup, Ole, Van Kuijk, Jan P., Biscaglia, Simone, Mogensen, Lone J.H., Henareh, Loghman, Burzotta, Francesco, H. Eek, Christian, Mylotte, Darren, Llinas, Miquel S., Koltowski, Lukasz, Knaapen, Paul, Calic, Slobodan, Witt, Nils, Santos-Pardo, Irene, Watkins, Stuart, Lønborg, Jacob, Kristensen, Andreas T., Jensen, Lisette O., Calais, Fredrik, Cockburn, James, McNeice, Andrew, Kajander, Olli A., Heestermans, Ton, Kische, Stephan, Eftekhari, Ashkan, Spratt, James C., Christiansen, Evald H.

“…In patients with coronary bifurcation lesions, optical coherence tomography–guided PCI was associated with a lower incidence of major adverse cardiac events at…”
Get full text

Novel cardiac extracellular matrix biomarkers in STEMI: Associations with ischemic injury and long-term mortality by Andrup, Simon, Andersen, Geir Ø, Hoffmann, Pavel, Eritsland, Jan, Seljeflot, Ingebjørg, Halvorsen, Sigrun, Vistnes, Maria

“…We aimed to determine whether serum levels of proteins related to changes in cardiac extracellular matrix (ECM) were associated with ischemic injury assessed…”
Get full text

Neutrophil Extracellular Trap Components Associate with Infarct Size, Ventricular Function, and Clinical Outcome in STEMI by Seljeflot, Ingebjørg, Eritsland, Jan, Arnesen, Harald, Opstad, Trine B., Limalanathan, Shanmuganathan, Langseth, Miriam Sjåstad, Andersen, Geir Øystein, Shetelig, Christian, Helseth, Ragnhild, Hoffmann, Pavel

“…Background. The relevance of neutrophil extracellular traps (NETs) in acute ST-elevation myocardial infarction (STEMI) is unclear. We explored the temporal…”
Get full text

Neurohormonal Blockade and Circulating Cardiovascular Biomarkers During Anthracycline Therapy in Breast Cancer Patients: Results From the PRADA (Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy) Study by Gulati, Geeta, Heck, Siri L., Røsjø, Helge, Ree, Anne H., Hoffmann, Pavel, Hagve, Tor‐Arne, Norseth, Jon, Gravdehaug, Berit, Steine, Kjetil, Geisler, Jürgen, Omland, Torbjørn

“…Background Anthracyclines are associated with cardiotoxic effects. Cardiovascular biomarkers may reflect myocardial injury, dysfunction, inflammation, and…”
Get full text

High levels of interleukin-6 are associated with final infarct size and adverse clinical events in patients with STEMI by Tøllefsen, Ingvild Maria, Shetelig, Christian, Seljeflot, Ingebjørg, Eritsland, Jan, Hoffmann, Pavel, Andersen, Geir Øystein

“…ObjectiveInflammation has emerged as a new treatment target in patients with coronary artery disease and inflammation seems to play an important role in…”
Get full text

Osteoprotegerin levels in ST-elevation myocardial infarction: Temporal profile and association with myocardial injury and left ventricular function by Shetelig, Christian, Limalanathan, Shanmuganathan, Eritsland, Jan, Hoffmann, Pavel, Seljeflot, Ingebjørg, Gran, Jon Michael, Aukrust, Pål, Ueland, Thor, Andersen, Geir Øystein

“…Elevated levels of osteoprotegerin (OPG) have been associated with adverse outcomes in ST-elevation myocardial infarction (STEMI). However, the role of OPG in…”
Get full text

MR findings of microvascular perfusion in infarcted and remote myocardium early after successful primary PCI by Bethke, Anne, Shanmuganathan, Limalanathan, Shetelig, Christian, Swanson, David, Andersen, Geir Øystein, Eritsland, Jan, Kløw, Nils Einar, Hoffmann, Pavel

“…The aim of the study was to evaluate CMR myocardial first-pass perfusion in the injured region as well as the non-infarcted area in ST-elevation myocardial…”
Get full text

Gene expression of fibrinolytic markers in coronary thrombi by Nordeng, Jostein, Solheim, Svein, Åkra, Sissel, Schandiz, Hossein, Hoffmann, Pavel, Roald, Borghild, Bendz, Bjørn, Arnesen, Harald, Helseth, Ragnhild, Seljeflot, Ingebjørg

“…The fibrinolytic system plays an important role in coronary artery atherothrombosis, and especially circulating plasminogen-activator inhibitor (PAI) type 1…”
Get full text

Renal sympathetic denervation lowers systemic vascular resistance in true treatment-resistant hypertension by Kaja K. Bergo, Anne C. Larstorp, Pavel Hoffmann, Ulla Hjørnholm, Alessandro Cataliotti, Aud Høieggen, Morten Rostrup, Fadl Elmula M. Fadl Elmula

“…Purpose Renal sympathetic denervation (RDN) is again gaining interest as recent well-designed trials have demonstrated reduced ambulatory blood pressure (BP)…”
Get full text

Access site complications after transfemoral aortic valve implantation - a comparison of Manta and ProGlide by Hoffmann, Pavel, Al-Ani, Ahmed, von Lueder, Thomas, Hoffmann, Jenny, Majak, Peter, Hagen, Ove, Loose, Helga, Kløw, Nils Einar, Opdahl, Anders

“…Background Despite decreasing sheath diameter, access site bleeding and vascular complications are still a major concern in transfemoral aortic valve…”
Get full text

Sample Size in Clinical Cardioprotection Trials Using Myocardial Salvage Index, Infarct Size, or Biochemical Markers as Endpoint by Engblom, Henrik, Heiberg, Einar, Erlinge, David, Jensen, Svend Eggert, Nordrehaug, Jan Erik, Dubois‐Randé, Jean‐Luc, Halvorsen, Sigrun, Hoffmann, Pavel, Koul, Sasha, Carlsson, Marcus, Atar, Dan, Arheden, Håkan

“…Background Cardiac magnetic resonance (CMR) can quantify myocardial infarct (MI) size and myocardium at risk (MaR), enabling assessment of myocardial salvage…”
Get full text

Myocardial salvage is reduced in primary PCI-treated STEMI patients with microvascular obstruction, demonstrated by early and late CMR by Limalanathan, Shanmuganathan, Eritsland, Jan, Andersen, Geir Øystein, Kløw, Nils-Einar, Abdelnoor, Michael, Hoffmann, Pavel

“…This study evaluates the association between microvascular obstruction and myocardial salvage, determined by cardiac magnetic resonance performed both in the…”
Get full text

The Time Profile of Pentraxin 3 in Patients with Acute ST-Elevation Myocardial Infarction and Stable Angina Pectoris Undergoing Percutaneous Coronary Intervention by Arnesen, Harald, Hoffmann, Pavel, Opstad, Trine, Solheim, Svein, Helseth, Ragnhild, Seljeflot, Ingebjørg

“…Background. High levels of Pentraxin 3 (PTX3) are reported in acute myocardial infarction (AMI). Aim. To investigate circulating levels and gene expression of…”
Get full text

Extreme altitude induces divergent mass reduction of right and left ventricle in mountain climbers by Udjus, Camilla, Sjaastad, Ivar, Hjørnholm, Ulla, Tunestveit, Torbjørn K., Hoffmann, Pavel, Hinojosa, Alexis, Espe, Emil K. S., Christensen, Geir, Skjønsberg, Ole H., Larsen, Karl‐Otto, Rostrup, Morten

“…Mountain climbing at high altitude implies exposure to low levels of oxygen, low temperature, wind, physical and psychological stress, and nutritional…”
Get full text

Rationale and design of the POSTEMI (postconditioning in ST-elevation myocardial infarction) study by Limalanathan, Shanmuganathan, Andersen, Geir Øystein, Hoffmann, Pavel, Kløw, Nils-Einar, Abdelnoor, Michael, Eritsland, Jan

“…Rapid reperfusion of the infarct-related coronary artery is essential in the treatment of acute ST-elevation myocardial infarction (STEMI). Paradoxically,…”
Get more information

Left ventricular function in acute myocardial infarction treated with thrombolysis followed by early versus late invasive strategy by Mistry, Nisha, MD, Bøhmer, Ellen, MD, Hoffmann, Pavel, MD, PhD, Müller, Carl, MD, Bjørnerheim, Reidar, MD, PhD, Kjeldsen, Sverre E., MD, PhD, Halvorsen, Sigrun, MD, PhD

“…Background Thrombolysis remains the treatment of choice in acute ST-segment elevation myocardial infarction (STEMI) when primary percutaneous coronary…”
Get full text

Cardiac magnetic resonance visualizes acute and chronic myocardial injuries in myocarditis by Stensaeth, Knut Haakon, Hoffmann, Pavel, Fossum, Eigil, Mangschau, Arild, Sandvik, Leiv, Klow, Nils Einar

Get full text

Efficacy and Safety of Immediate Angioplasty Versus Ischemia-Guided Management After Thrombolysis in Acute Myocardial Infarction in Areas With Very Long Transfer Distances by Bøhmer, Ellen, MD, Hoffmann, Pavel, MD, PhD, Abdelnoor, Michael, PhD, Arnesen, Harald, MD, PhD, Halvorsen, Sigrun, MD, PhD

“…Objectives The goal of this study was to compare a strategy of immediate transfer for percutaneous coronary intervention (PCI) with an ischemia-guided approach…”
Get full text

Amino-Terminal Pro–B-Type Natriuretic Peptide (NT-proBNP) Levels 3 Months After Myocardial Infarction Are More Strongly Associated With Magnetic Resonance–Determined Ejection Fraction Than NTproBNP Levels in the Acute Phase by Mistry, Nisha, MD, Abdelnoor, Michael, MD, PhD, Seljeflot, Ingebjørg, MD, PhD, Hoffmann, Pavel, MD, PhD, Bøhmer, Ellen, MD, Bjørnerheim, Reidar, MD, PhD, Kjeldsen, Sverre E., MD, PhD, Halvorsen, Sigrun, MD, PhD

“…Abstract Background The relationship between levels of amino-terminal pro–B-type natriuretic peptide (NT-proBNP) and left ventricular function determined by…”
Get full text