Search Results - "Hoffmann, Jürgen"

Basophil activation test: Mechanisms and considerations for use in clinical trials and clinical practice by Santos, Alexandra F., Alpan, Oral, Hoffmann, Hans‐Jürgen

“…The basophil activation test (BAT) is a functional assay that measures the degree of degranulation following stimulation with allergen or controls by flow…”
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Intralymphatic immunotherapy improves grass pollen allergic rhinoconjunctivitis: A 3-year randomized placebo-controlled trial by Skaarup, Søren Helbo, Schmid, Johannes Martin, Skjold, Tina, Graumann, Ole, Hoffmann, Hans Jürgen

“…Allergic rhinoconjunctivitis is a global health problem. Different allergen immunotherapy regimes are marketed but have low adherence because they are…”
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Is the conservative non-surgical management of medication-related osteonecrosis of the jaw an appropriate treatment option for early stages? A long-term single-center cohort study by Ristow, Oliver, Rückschloß, Thomas, Müller, Michael, Berger, Moritz, Kargus, Steffen, Pautke, Christoph, Engel, Michael, Hoffmann, Jürgen, Freudlsperger, Christian

“…No consensus has been reached regarding the best treatment option for early-stage lesions in medication-related osteonecrosis of the jaw (MRONJ). The purpose…”
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Treatment delay and tumor size in patients with oral cancer during the first year of the COVID‐19 pandemic by Metzger, Karl, Mrosek, Jan, Zittel, Sven, Pilz, Maximilian, Held, Thomas, Adeberg, Sebastian, Ristow, Oliver, Hoffmann, Jürgen, Engel, Michael, Freudlsperger, Christian, Moratin, Julius

“…Background We set out to investigate how the ongoing coronavirus pandemic affected the size of tumors and the duration of treatment delay in patients with…”
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Interleukin‐6 promotes tumorigenesis by altering DNA methylation in oral cancer cells by Gasche, Jacqueline A., Hoffmann, Jürgen, Boland, C. Richard, Goel, Ajay

“…Worldwide oral squamous cell carcinoma (OSCC) accounts for more than 100,000 deaths each year. Chronic inflammation constitutes one of the key risk factors for…”
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SARS‐CoV‐2 evades immune detection in alveolar macrophages by Dalskov, Louise, Møhlenberg, Michelle, Thyrsted, Jacob, Blay‐Cadanet, Julia, Poulsen, Ebbe Toftgaard, Folkersen, Birgitte Holst, Skaarup, Søren Helbo, Olagnier, David, Reinert, Line, Enghild, Jan Johannes, Hoffmann, Hans Jürgen, Holm, Christian Kanstrup, Hartmann, Rune

“…Respiratory infections, like the current COVID‐19 pandemic, target epithelial cells in the respiratory tract. Alveolar macrophages (AMs) are tissue‐resident…”
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The Influence of Different Graft Designs of Intraoral Bone Blocks on Volume Gain in Bone Augmentation Procedures: An In Vitro Study by Kalchthaler, Lukas, Kühle, Reinald, Büsch, Christopher, Hoffmann, Jürgen, Mertens, Christian

“…Intraoral bone blocks from the external oblique are the gold standard for alveolar ridge bone grafting, but the limited amount of available bone limits their…”
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Classifying breast cancer surgery: a novel, complexity-based system for oncological, oncoplastic and reconstructive procedures, and proof of principle by analysis of 1225 operations in 1166 patients by Hoffmann, Jürgen, Wallwiener, Diethelm

“…One of the basic prerequisites for generating evidence-based data is the availability of classification systems. Attempts to date to classify breast cancer…”
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Basophil sensitivity reflects long‐term clinical outcome of subcutaneous immunotherapy in grass pollen‐allergic patients by Schmid, Johannes M., Würtzen, Peter A., Siddhuraj, Premkumar, Jogdand, Prajakta, Petersen, Claus G., Dahl, Ronald, Erjefält, Jonas S., Hoffmann, Hans Jürgen

“…Background Allergic rhinoconjunctivitis is a public health problem. Allergen Immunotherapy is an effective and safe treatment, that modifies the natural course…”
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Health-related quality of life in children after surgical treatment of non-syndromal craniosynostosis by Shavlokhova, Veronika, Grüninger, Steffen, Hoffmann, Jürgen, Freudlsperger, Christian, Engel, Michael

“…Craniosynostosis is a premature ossification of the fibrous sutures in a skull which results in a changing of the growth pattern of the skull with abnormal…”
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Development and application of a highly sensitive LC-MS/MS method for simultaneous quantification of N,N-dimethyltryptamine and two of its metabolites in human plasma by Eckernäs, Emma, Bendrioua, Adam, Cancellerini, Chiara, Timmermann, Christopher, Carhart-Harris, Robin, Hoffmann, Kurt-Jürgen, Ashton, Michael

“…A highly sensitive LC-MS/MS method for the quantification of N,N-dimethyltryptamine (DMT) and its metabolites indole-3-acetic acid and DMT N-oxide in human…”
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Clinical outcome and prognostic factors in recurrent oral squamous cell carcinoma after primary surgical treatment: a retrospective study by Zittel, Sven, Moratin, Julius, Horn, Dominik, Metzger, Karl, Ristow, Oliver, Engel, Michael, Mrosek, Jan, Freier, Kolja, Hoffmann, Jürgen, Freudlsperger, Christian

“…Objectives Survival for patients with recurrent oral squamous cell carcinoma is usually poor, and the most effective treatment has not yet been clearly…”
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Diagnostic accuracy comparing OPT and CBCT in the detection of non‐vital bone changes before tooth extractions in patients with antiresorptive intake by Ristow, Oliver, Schnug, Gregor, Smielowksi, Maximilian, Moratin, Julius, Pilz, Maximilian, Engel, Michael, Freudlsperger, Christian, Hoffmann, Jürgen, Rückschloß, Thomas

“…Objectives To compare the diagnostic accuracy in detecting early non‐vital bone changes between orthopantomography (OPT) and cone‐beam computed tomography…”
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Factors Affecting the Pharmacokinetics of Pyrazinamide and Its Metabolites in Patients Coinfected with HIV and Implications for Individualized Dosing by Sundell, Jesper, Wijk, Marie, Bienvenu, Emile, Äbelö, Angela, Hoffmann, Kurt-Jürgen, Ashton, Michael

“…Pyrazinamide is a first-line drug used in the treatment of tuberculosis. High exposure to pyrazinamide and its metabolites may result in hepatotoxicity,…”
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Multiple Sequential Free Flap Reconstructions of the Head and Neck: A Single-Center Experience by Moratin, Julius, Horn, Dominik, Heinemann, Maleen, Metzger, Karl, Mrosek, Jan, Ristow, Oliver, Engel, Michael, Freudlsperger, Christian, Freier, Kolja, Hoffmann, Jürgen

“…Free flap reconstruction is the standard of care in extensive defects of the head and neck area, and although most patients may be treated sufficiently with…”
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3D-2D Distance Maps Conversion Enhances Classification of Craniosynostosis by Schaufelberger, Matthias, Kaiser, Christian, Kuhle, Reinald, Wachter, Andreas, Weichel, Frederic, Hagen, Niclas, Ringwald, Friedemann, Eisenmann, Urs, Hoffmann, Jorgen, Engel, Michael, Freudlsperger, Christian, Nahm, Werner

“…Objective: Diagnosis of craniosynostosis using photogrammetric 3D surface scans is a promising radiation-free alternative to traditional computed tomography…”
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Reconstruction of the severely atrophic edentulous maxillae with calvarial bone grafts by Mertens, Christian, Freier, Kolja, Engel, Michael, Krisam, Johannes, Hoffmann, Jürgen, Freudlsperger, Christian

“…Objectives Treatment of the severely atrophic maxilla with dental implants is challenging due to the insufficient horizontal and vertical bone volume and…”
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Early bone resorption after vertical bone augmentation - a comparison of calvarial and iliac grafts by Mertens, Christian, Decker, Christian, Seeberger, Robin, Hoffmann, Jürgen, Sander, Anja, Freier, Kolja

“…Objective and aim Severe cases of bone atrophy in the maxilla or mandible are often reconstructed using bone from extraoral donor sides. Most commonly, grafts…”
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The number and affinity of productive IgE pairs determine allergen activation of mast cells by Hjort, Charlotte, BSc(Med), Schiøtz, Peter Oluf, MD, Ohlin, Mats, PhD, Würtzen, Peter Adler, PhD, Christensen, Lars Harder, PhD, Hoffmann, Hans Jürgen, PhD

“…The positive correlation between Fc[epsilon]RI density and plasma IgE concentration underlines the importance of IgE antibodies in activation of mast cells.1…”
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Features of oral squamous cell carcinoma in ex vivo fluorescence confocal microscopy by Shavlokhova, Veronika, Flechtenmacher, Christa, Sandhu, Sameena, Vollmer, Michael, Hoffmann, Jürgen, Engel, Michael, Ristow, Oliver, Freudlsperger, Christian

“…Background Real‐time microscopic imaging of freshly excised oral squamous cell carcinomas (OSCCs) would be potentially supportive in rapid recognition of oral…”
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