Search Results - "Hoffman, Pauline"
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Mosaic nanoparticles elicit cross-reactive immune responses to zoonotic coronaviruses in mice
Published in Science (American Association for the Advancement of Science) (12-02-2021)“…Protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and SARS-related emergent zoonotic coronaviruses is urgently needed. We made…”
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Convergent antibody responses to SARS-CoV-2 in convalescent individuals
Published in Nature (London) (20-08-2020)“…During the coronavirus disease-2019 (COVID-19) pandemic, severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) has led to the infection of…”
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Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies
Published in Cell (20-08-2020)“…Neutralizing antibody responses to coronaviruses mainly target the receptor-binding domain (RBD) of the trimeric spike. Here, we characterized polyclonal…”
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Polyaniline-polycaprolactone blended nanofibers for neural cell culture
Published in European polymer journal (01-08-2019)“…[Display omitted] •Electroconductive PCL-PANI nanofibers can be produced using TFE.•PCL-PANI fibers are characterized using FTIR, TGA, DSC, Mechanical…”
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The effect of electrospun scaffolds on the glycosaminoglycan profile of differentiating neural stem cells
Published in Biochimie (01-03-2021)“…The use of electrospun scaffolds for neural tissue engineering applications allows a closer mimicry of the native tissue extracellular matrix (ECM), important…”
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Polybenzimidazole nanofibers for neural stem cell culture
Published in Materials today chemistry (01-12-2019)“…Neurodegenerative diseases compromise the quality of life of an increasing number of people in the world's aging population. While diagnosis is possible, no…”
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CNSC-63. THE COMPLEX RELATIONSHIP BETWEEN GENETIC ETIOLOGIES OF GLIOBLASTOMA AND PATIENT SURVIVAL: A RETROSPECTIVE ANALYSIS
Published in Neuro-oncology (Charlottesville, Va.) (11-11-2024)“…Data Analysis was done using the NIH GDC Data Portal with glioblastomas being the only selected primary diagnosis (n=1381). Kaplan Meier plots were generated…”
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Aberrant methylmalonylation underlies methylmalonic acidemia and is attenuated by an engineered sirtuin
Published in Science translational medicine (25-05-2022)“…Organic acidemias such as methylmalonic acidemia (MMA) are a group of inborn errors of metabolism that typically arise from defects in the catabolism of amino…”
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Glycosaminoglycans from bovine eye vitreous humour and interaction with collagen type II
Published in Glycoconjugate journal (01-02-2018)“…Glycosaminoglycans (GAGs) play an important role in stabilizing the gel state of eye vitreous humour. In this study, the composition of GAGs present in bovine…”
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Polyaniline-polycaprolactone fibers for neural applications: Electroconductivity enhanced by pseudo-doping
Published in Materials Science & Engineering C (01-01-2021)“…Replenishing neurons in patients with neurodegenerative diseases is one of the ultimate therapies for these progressive, debilitating and fatal diseases…”
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