Search Results - "Hoffman, Jessie"
-
1
Dioxin-like PCB 126 increases intestinal inflammation and disrupts gut microbiota and metabolic homeostasis
Published in Environmental pollution (1987) (01-11-2018)“…The gut microbiome is sensitive to diet and environmental exposures and is involved in the regulation of host metabolism. Additionally, gut inflammation is an…”
Get full text
Journal Article -
2
Protective influence of healthful nutrition on mechanisms of environmental pollutant toxicity and disease risks
Published in Annals of the New York Academy of Sciences (01-06-2017)“…Human exposures to environmental contaminants around the world contribute to the global burden of disease and thus require urgent attention. Exploring…”
Get full text
Journal Article -
3
Environmental pollutant-mediated disruption of gut microbial metabolism of the prebiotic inulin
Published in Anaerobe (01-02-2019)“…Exposure to environmental pollutants is associated with a greater risk for metabolic diseases including cardiovascular disease. Pollutant exposure can also…”
Get full text
Journal Article -
4
Dietary inulin decreases circulating ceramides by suppressing neutral sphingomyelinase expression and activity in mice
Published in Journal of lipid research (01-01-2020)“…Elevated circulating levels of ceramides (Cers) are associated with increased risk of cardiometabolic diseases, and Cers may play a causative role in metabolic…”
Get full text
Journal Article -
5
Prebiotic inulin consumption reduces dioxin-like PCB 126-mediated hepatotoxicity and gut dysbiosis in hyperlipidemic Ldlr deficient mice
Published in Environmental pollution (1987) (01-06-2020)“…Exposure to some environmental pollutants increases the risk of developing inflammatory disorders such as steatosis and cardiometabolic diseases. Diets high in…”
Get full text
Journal Article -
6
A Compromised Liver Alters Polychlorinated Biphenyl-Mediated Toxicity
Published in Toxicology (Amsterdam) (01-04-2017)“…Graphical abstract…”
Get full text
Journal Article -
7
A polyphenol-rich fraction obtained from table grapes decreases adiposity, insulin resistance and markers of inflammation and impacts gut microbiota in high-fat-fed mice
Published in The Journal of nutritional biochemistry (01-05-2016)“…The objective of this study was to determine if consuming an extractable or nonextractable fraction of table grapes reduced the metabolic consequences of…”
Get full text
Journal Article -
8
Factors Associated with Provider Practices Related to Infant Feeding in Primary Care Settings: Results from a Pilot Survey
Published in Nutrients (01-01-2024)“…In 2020, only 25.6% of dyads in the US were exclusively breastfeeding at six months. Previous research has shown that breastfeeding continuation improves when…”
Get full text
Journal Article -
9
Impact of nutrition on pollutant toxicity: an update with new insights into epigenetic regulation
Published in Reviews on environmental health (01-03-2017)“…Exposure to environmental pollutants is a global health problem and is associated with the development of many chronic diseases, including cardiovascular…”
Get more information
Journal Article -
10
Dioxin-like pollutants increase hepatic flavin containing monooxygenase (FMO3) expression to promote synthesis of the pro-atherogenic nutrient biomarker trimethylamine N-oxide from dietary precursors
Published in The Journal of nutritional biochemistry (01-07-2016)“…The etiology of cardiovascular disease (CVD) is impacted by multiple modifiable and non-modifiable risk factors including dietary choices, genetic…”
Get full text
Journal Article -
11
Emerging roles of xenobiotic detoxification enzymes in metabolic diseases
Published in Reviews on environmental health (01-03-2017)“…Mammalian systems have developed extensive molecular mechanisms to protect against the toxicity of many exogenous xenobiotic compounds. Interestingly, many…”
Get more information
Journal Article -
12
Preliminary Investigation of Microbiome and Dietary Differences in Patients with Phenylketonuria on Enzyme Substitution Therapy Compared to Traditional Therapies
Published in Journal of the Academy of Nutrition and Dietetics (01-07-2022)“…Phenylketonuria (PKU) is an inborn error of metabolism that impairs the function of the enzyme phenylalanine hydroxylase. Historical treatment includes…”
Get full text
Journal Article -
13
Bridging Disciplines with a New and Interactive Online Course: Drug & Nutrient Interactions
Published in Current developments in nutrition (01-06-2020)“…The purpose of this project was to design, develop and implement an online two-credit course, Drug & Nutrient Interactions, as an elective for a new online…”
Get full text
Journal Article -
14
PCB126 Exposure Modulates Gut Microbial Fermentation of the Dietary Fiber Inulin
Published in The FASEB journal (01-04-2017)“…Abstract only Exposure to environmental pollutants is associated with a greater risk for metabolic diseases including cardiovascular disease. Pollutant…”
Get full text
Journal Article -
15
Dioxin-like PCB 126 Increases Systemic Inflammation and Accelerates Atherosclerosis in Lean LDL Receptor-Deficient Mice
Published in Toxicological sciences (01-04-2018)“…Abstract Exposure to dioxins and related persistent organic pollutants likely contributes to cardiovascular disease (CVD) risk through multiple mechanisms…”
Get full text
Journal Article -
16
Butyrate Modulates Cav‐1 and Its Binding Partner AhR, Leading to Differential Cyp1a1 and Cyp1b1 Gene Expression in Vascular Endothelial Cells
Published in The FASEB journal (01-04-2016)“…Abstract only Dietary fiber and associated metabolites such as butyrate may protect against vascular inflammation and atherosclerosis. The vascular endothelium…”
Get full text
Journal Article -
17
Maternal polychlorinated biphenyl 126 (PCB 126) exposure modulates offspring gut microbiota irrespective of diet and exercise
Published in Reproductive toxicology (Elmsford, N.Y.) (01-06-2023)“…The gut microbiota plays an important role throughout the lifespan in maintaining host health, and several factors can modulate microbiota composition…”
Get full text
Journal Article -
18
-
19
Editor's Highlight: PCB126 Exposure Increases Risk for Peripheral Vascular Diseases in a Liver Injury Mouse Model
Published in Toxicological sciences (01-12-2017)“…The liver is vital for xenobiotic and endobiotic metabolism. Previously, we demonstrated that a compromised liver worsened toxicity associated with exposure to…”
Get full text
Journal Article -
20
The Prebiotic Inulin Beneficially Alters the Gut Microbiome and Associated Metabolites in an APOE4 Mouse Model (P08-133-19)
Published in Current developments in nutrition (01-06-2019)“…The APOE4 allele is a genetic risk factor for certain diseases, due in part to alterations in lipid and glucose metabolism. The gut microbiota is also known to…”
Get full text
Journal Article