Search Results - "Hoffman, D."

Fibroblasts drive an immunosuppressive and growth-promoting microenvironment in breast cancer via secretion of Chitinase 3-like 1 by Cohen, N, Shani, O, Raz, Y, Sharon, Y, Hoffman, D, Abramovitz, L, Erez, N

“…Cancer-Associated Fibroblasts (CAFs) are the most prominent stromal cell type in breast tumors. CAFs promote tumor growth and metastasis by multiple…”
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Stan: A Probabilistic Programming Language by Carpenter, Bob, Gelman, Andrew, Hoffman, Matthew D, Lee, Daniel, Goodrich, Ben, Betancourt, Michael, Brubaker, Marcus A, Guo, Jiqiang, Li, Peter, Riddell, Allen

“…Stan is a probabilistic programming language for specifying statistical models. A Stan program imperatively defines a log probability function over parameters…”
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Towards a Dynamic Understanding of Cadherin-Based Mechanobiology by Hoffman, Brenton D, Yap, Alpha S

“…Cadherin-based cell–cell adhesions are a primary determinant of tissue structure. For several decades, it had been thought that the primary function of these…”
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Modifications for the fisher technique for unilateral cleft repair by Hoffman, D

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Graphical translators for mean curvature flow by Hoffman, D., Ilmanen, T., Martín, F., White, B.

“…In this paper we provide a full classification of complete translating graphs in R 3 . We also construct ( n - 1 ) -parameter families of new examples of…”
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Health and exercise-related medical issues among 1,212 ultramarathon runners: baseline findings from the Ultrarunners Longitudinal TRAcking (ULTRA) Study by Hoffman, Martin D, Krishnan, Eswar

“…Regular exercise is associated with substantial health benefits; however, little is known about the health impact of extreme levels of exercise. This study…”
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Interfacing consciousness by Prentner, Robert, Hoffman, Donald D

“…The current stage of consciousness science has reached an impasse. We blame the physicalist worldview for this and propose a new perspective to make progress…”
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Cell mechanics: dissecting the physical responses of cells to force by Hoffman, Brenton D, Crocker, John C

“…It is now widely appreciated that normal tissue morphology and function rely upon cells' ability to sense and generate forces appropriate to their correct…”
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Macrophage migration inhibitory factor downregulation: a novel mechanism of resistance to anti-angiogenic therapy by Castro, B A, Flanigan, P, Jahangiri, A, Hoffman, D, Chen, W, Kuang, R, De Lay, M, Yagnik, G, Wagner, J R, Mascharak, S, Sidorov, M, Shrivastav, S, Kohanbash, G, Okada, H, Aghi, M K

“…Anti-angiogenic therapies for cancer such as VEGF neutralizing antibody bevacizumab have limited durability. While mechanisms of resistance remain undefined,…”
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Vinculin Force-Sensitive Dynamics at Focal Adhesions Enable Effective Directed Cell Migration by Rothenberg, Katheryn E., Scott, David W., Christoforou, Nicolas, Hoffman, Brenton D.

“…Cell migration is a complex process, requiring coordination of many subcellular processes including membrane protrusion, adhesion, and contractility. For…”
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Consumption of ultra-processed food products and its effects on children's lipid profiles: A longitudinal study by Rauber, F, Campagnolo, P.D.B, Hoffman, D.J, Vitolo, M.R

“…Abstract Background and Aims Cardiovascular disease development is related to known risk factors (such as diet and blood lipids) that begin in childhood. Among…”
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Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics by Ha, Taekjip, Schwartz, Martin A, Grashoff, Carsten, Hoffman, Brenton D, Brenner, Michael D, Zhou, Ruobo, Parsons, Maddy, Yang, Michael T, McLean, Mark A, Sligar, Stephen G, Chen, Christopher S

“…Mechanical forces are central to developmental, physiological and pathological processes. However, limited understanding of force transmission within…”
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DHA and ARA addition to infant formula: Current status and future research directions by Lien, E.L., Richard, C., Hoffman, D.R.

“…Docosahexaenoic acid (DHA) and arachidonic acid (ARA) are present in breast milk and play important roles in early infant development. A supply of these fatty…”
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The health status burden of people with fibromyalgia: a review of studies that assessed health status with the SF-36 or the SF-12 by Hoffman, D L, Dukes, E M

“…The current review describes how the health status profile of people with fibromyalgia (FM) compares to that of people in the general population and patients…”
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Tension-Sensitive Actin Assembly Supports Contractility at the Epithelial Zonula Adherens by Leerberg, Joanne M., Gomez, Guillermo A., Verma, Suzie, Moussa, Elliott J., Wu, Selwin K., Priya, Rashmi, Hoffman, Brenton D., Grashoff, Carsten, Schwartz, Martin A., Yap, Alpha S.

“…Actomyosin-based contractility acts on cadherin junctions to support tissue integrity and morphogenesis. The actomyosin apparatus of the epithelial zonula…”
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Fulminant Myocarditis with Combination Immune Checkpoint Blockade by Johnson, Douglas B, Balko, Justin M, Compton, Margaret L, Chalkias, Spyridon, Gorham, Joshua, Xu, Yaomin, Hicks, Mellissa, Puzanov, Igor, Alexander, Matthew R, Bloomer, Tyler L, Becker, Jason R, Slosky, David A, Phillips, Elizabeth J, Pilkinton, Mark A, Craig-Owens, Laura, Kola, Nina, Plautz, Gregory, Reshef, Daniel S, Deutsch, Jonathan S, Deering, Raquel P, Olenchock, Benjamin A, Lichtman, Andrew H, Roden, Dan M, Seidman, Christine E, Koralnik, Igor J, Seidman, Jonathan G, Hoffman, Robert D, Taube, Janis M, Diaz, Luis A, Anders, Robert A, Sosman, Jeffrey A, Moslehi, Javid J

“…Fatal autoimmune myocarditis with rhabdomyolysis and refractory arrhythmias developed in two patients treated with a combination of anti–CTLA-4 and anti–PD-1…”
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The effect of mesenchymal stem cells delivered via hydrogel-based tissue engineered periosteum on bone allograft healing by Hoffman, Michael D, Xie, Chao, Zhang, Xinping, Benoit, Danielle S.W

“…Abstract Allografts remain the clinical “gold standard” for treatment of critical sized bone defects despite minimal engraftment and ∼60% long-term failure…”
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Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts by Rashkin, Sara R., Graff, Rebecca E., Kachuri, Linda, Thai, Khanh K., Alexeeff, Stacey E., Blatchins, Maruta A., Cavazos, Taylor B., Corley, Douglas A., Emami, Nima C., Hoffman, Joshua D., Jorgenson, Eric, Kushi, Lawrence H., Meyers, Travis J., Van Den Eeden, Stephen K., Ziv, Elad, Habel, Laurel A., Hoffmann, Thomas J., Sakoda, Lori C., Witte, John S.

“…Deciphering the shared genetic basis of distinct cancers has the potential to elucidate carcinogenic mechanisms and inform broadly applicable risk assessment…”
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Integrated Nucleosynthesis in Neutrino-driven Winds by Roberts, L. F, Woosley, S. E, Hoffman, R. D

“…Although they are but a small fraction of the mass ejected in core-collapse supernovae, neutrino-driven winds (NDWs) from nascent proto-neutron stars (PNSs)…”
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Patient re-contact after revision of genomic test results: points to consider—a statement of the American College of Medical Genetics and Genomics (ACMG) by David, Karen L., Best, Robert G., Brenman, Leslie Manace, Bush, Lynn, Deignan, Joshua L., Flannery, David, Hoffman, Jodi D., Holm, Ingrid, Miller, David T., O’Leary, James, Pyeritz, Reed E.

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