Search Results - "Hoffman, Benjamin U"
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Significant relaxation of SARS-CoV-2-targeted non-pharmaceutical interventions may result in profound mortality: A New York state modelling study
Published in PloS one (24-09-2020)“…Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) is the most significant global health crisis of the 21st century. The aim of this study was to…”
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The cellular basis of mechanosensation in mammalian tongue
Published in Cell reports (Cambridge) (28-02-2023)“…Mechanosensory neurons that innervate the tongue provide essential information to guide feeding, speech, and social grooming. We use in vivo calcium imaging of…”
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Computation predicts rapidly adapting mechanotransduction currents cannot account for tactile encoding in Merkel cell-neurite complexes
Published in PLoS computational biology (01-06-2018)“…Distinct firing properties among touch receptors are influenced by multiple, interworking anatomical structures. Our understanding of the functions and…”
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The signaling lipid sphingosine 1-phosphate regulates mechanical pain
Published in eLife (21-03-2018)“…Somatosensory neurons mediate responses to diverse mechanical stimuli, from innocuous touch to noxious pain. While recent studies have identified distinct…”
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Focused ultrasound excites action potentials in mammalian peripheral neurons in part through the mechanically gated ion channel PIEZO2
Published in Proceedings of the National Academy of Sciences - PNAS (24-05-2022)“…Neurons of the peripheral nervous system (PNS) are tasked with diverse roles, from encoding touch, pain, and itch to interoceptive control of inflammation and…”
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A gut feeling
Published in Science (American Association for the Advancement of Science) (21-09-2018)“…Gut-brain signaling involves neurotransmission from gut sensory epithelial cells The anatomist Friedrich S. Merkel predicted in 1880 that sensory systems are…”
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In vitro production of infectious Plasmodium falciparum sporozoites
Published in Nature (London) (15-12-2022)“…An effective vaccine is needed for the prevention and elimination of malaria. The only immunogens that have been shown to have a protective efficacy of more…”
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Merkel Cells Activate Sensory Neural Pathways through Adrenergic Synapses
Published in Neuron (Cambridge, Mass.) (19-12-2018)“…Epithelial-neuronal signaling is essential for sensory encoding in touch, itch, and nociception; however, little is known about the release mechanisms and…”
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Plasmodium falciparum: Effect of radiation on levels of gene transcripts in sporozoites
Published in Experimental parasitology (01-02-2008)“…Humans immunized by the bites of irradiated Plasmodium falciparum (Pf) sporozoite-infected mosquitoes are protected against malaria. Radiation attenuates the…”
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AI-BASED ECG AND COMPUTED TOMOGRAPHY MAPPING TO GUIDE SUCCESSFUL EPICARDIAL VENTRICULAR TACHYCARDIA ABLATION
Published in Journal of the American College of Cardiology (02-04-2024)Get full text
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Focused Ultrasound Evoked Responses in Dorsal Root Ganglion Neurons (DRG) and HEK293 Cells
Published in Biophysical journal (02-02-2018)Get full text
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The Peripheral Nervous System: From Molecular Mechanisms to Non-Invasive Therapeutics
Published 01-01-2019“…The peripheral nervous system (PNS) is composed of a diverse array of neurons that mediate sensation. This includes sensory circuits that encode external…”
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Dissertation