Search Results - "Hoferova, Zuzana"

Nitro-Oleic Acid Inhibits Stemness Maintenance and Enhances Neural Differentiation of Mouse Embryonic Stem Cells via STAT3 Signaling by Pereckova, Jana, Pekarova, Michaela, Szamecova, Nikoletta, Hoferova, Zuzana, Kamarytova, Kristyna, Falk, Martin, Perecko, Tomas

“…Nitro-oleic acid (NO2-OA), pluripotent cell-signaling mediator, was recently described as a modulator of the signal transducer and activator of transcription 3…”
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The role of adenosine receptor agonists in regulation of hematopoiesis by Hofer, Michal, Pospisil, Milan, Weiterova, Lenka, Hoferova, Zuzana

“…The review summarizes data evaluating the role of adenosine receptor signaling in murine hematopoietic functions. The studies carried out utilized either…”
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Brief Story on Prostaglandins, Inhibitors of their Synthesis, Hematopoiesis, and Acute Radiation Syndrome by Hofer, Michal, Hoferová, Zuzana, Falk, Martin

“…Prostaglandins and inhibitors of their synthesis (cyclooxygenase (COX) inhibitors, non-steroidal anti-inflammatory drugs) were shown to play a significant role…”
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Pharmacological Modulation of Radiation Damage. Does It Exist a Chance for Other Substances than Hematopoietic Growth Factors and Cytokines? by Hofer, Michal, Hoferová, Zuzana, Falk, Martin

“…In recent times, cytokines and hematopoietic growth factors have been at the center of attention for many researchers trying to establish pharmacological…”
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Combining Pharmacological Countermeasures to Attenuate the Acute Radiation Syndrome-A Concise Review by Hofer, Michal, Hoferová, Zuzana, Depeš, Daniel, Falk, Martin

“…The goal of combined pharmacological approaches in the treatment of the acute radiation syndrome (ARS) is to obtain an effective therapy producing a minimum of…”
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Cell-type specific anti-cancerous effects of nitro-oleic acid and its combination with gamma irradiation by Perecko, Tomas, Pereckova, Jana, Hoferova, Zuzana, Falk, Martin

“…Nitro-fatty acids (NFAs) are endogenous lipid mediators capable of post-translational modifications of selected regulatory proteins. Here, we investigated the…”
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Administration of nitro-oleic acid mitigates radiation-induced hematopoietic injury in mice by Perecko, Tomas, Hoferova, Zuzana, Hofer, Michal, Pereckova, Jana, Falk, Martin

“…Limited number of agents that provide protection against hematopoietic acute radiation syndrome led us to the evaluation of nitro-oleic acid (NO2OA) as a…”
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Granulocyte colony-stimulating factor in the treatment of acute radiation syndrome: a concise review by Hofer, Michal, Pospíšil, Milan, Komůrková, Denisa, Hoferová, Zuzana

“…This article concisely summarizes data on the action of one of the principal and best known growth factors, the granulocyte colony-stimulating factor (G-CSF),…”
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Stimulatory action of cyclooxygenase inhibitors on hematopoiesis: a review by Hofer, Michal, Pospíšil, Milan, Hoferová, Zuzana, Weiterová, Lenka, Komůrková, Denisa

“…The presented review summarizes experimental data obtained with a mouse model when investigating the relationship between inhibition of prostaglandin…”
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Nitro-oleic acid regulates differentiation of embryonic stem cells by Kamarytova, Kristyna, Kudova, Jana, Cechova, Veronika, Koreny, Martin, Hoferova, Zuzana, Freeman, Bruce, Pekarova, Michaela

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Casein kinase 1 is a therapeutic target in chronic lymphocytic leukemia by Janovska, Pavlina, Verner, Jan, Kohoutek, Jiri, Bryjova, Lenka, Gregorova, Michaela, Dzimkova, Marta, Skabrahova, Hana, Radaszkiewicz, Tomasz, Ovesna, Petra, Vondalova Blanarova, Olga, Nemcova, Tereza, Hoferova, Zuzana, Vasickova, Katerina, Smyckova, Lucie, Egle, Alexander, Pavlova, Sarka, Poppova, Lucie, Plevova, Karla, Pospisilova, Sarka, Bryja, Vitezslav

“…Casein kinase 1δ/ε (CK1δ/ε) is a key component of noncanonical Wnt signaling pathways, which were shown previously to drive pathogenesis of chronic lymphocytic…”
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Combined pharmacological therapy of the acute radiation disease using a cyclooxygenase-2 inhibitor and an adenosine A3 receptor agonist by Hofer Michal, Pospíšil Milan, Dušek Ladislav, Hoferová Zuzana, Komůrková Denisa

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Activation of adenosine A(3) receptors supports hematopoiesis-stimulating effects of granulocyte colony-stimulating factor in sublethally irradiated mice by Hofer, Michal, Pospísil, Milan, Sefc, Ludek, Dusek, Ladislav, Vacek, Antonín, Holá, Jirina, Hoferová, Zuzana, Streitová, Denisa

“…Research areas of 'post-exposure treatment' and 'cytokines and growth factors' have top priority among studies aimed at radiological nuclear threat…”
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The effect of nonsteroidal antiinflammatory drugs ibuprofen, flurbiprofen, and diclofenac on in vitro and in vivo growth of mouse fibrosarcoma by HOFEROVA, Zuzana, FEDOROCKO, Peter, HOFMANOVA, Jirina, HOFER, Michal, ZNOJIL, Vladimir, MINKSOVA, Katerina, SOUCEK, Karel, EGYED, Alena, KOZUBIK, Alois

“…For suppression of primary G:5:113 fibrosarcoma growth, three structurally different cyclooxygenase (COX) inhibitors (ibuprofen, flurbiprofen, and diclofenac)…”
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Tumor-Host Interactions Accompanying the Growth of the G:5:113 Fibrosarcoma in the Mouse: Possibilities for a New Therapeutic Approach? by Hoferová, Zuzana, Vacek, Antonín, Hofer, Michal, Macková, Nadezda O., Soucek, Karel, Egyed, Alena, Fedorocko, Peter

“…The experiments were aimed at describing in detail some interactions between a solid tumor growing from subcutaneously transplanted G:5:113 fibrosarcoma cells…”
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Lack of adenosine A3 receptors causes defects in mouse peripheral blood parameters by Hofer, Michal, Pospíšil, Milan, Dušek, Ladislav, Hoferová, Zuzana, Komůrková, Denisa

“…The role of the adenosine A 3 receptor in hematopoiesis was studied using adenosine A 3 receptor knockout (A 3 AR KO) mice. Hematological parameters of…”
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Agonist of the adenosine A3 receptor, IB-MECA, and inhibitor of cyclooxygenase-2, meloxicam, given alone or in a combination early after total body irradiation enhance survival of γ-irradiated mice by Hofer, Michal, Pospíšil, Milan, Dušek, Ladislav, Hoferová, Zuzana, Komůrková, Denisa

“…There exists a requirement for drugs which would be useful in therapy of an acute radiation damage of a mammalian organism. The aim of the study was to…”
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Inhibition of cyclooxygenase-2 promotes the stimulatory action of adenosine A 3 receptor agonist on hematopoiesis in sublethally γ-irradiated mice by Hofer, Michal, Pospíšil, Milan, Dušek, Ladislav, Hoferová, Zuzana, Weiterová, Lenka

“…Mouse hematopoiesis, suppressed by a sublethal dose of ionizing radiation, was the target for combined therapy with a cyclooxygenase-2 (COX-2) inhibitor…”
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Enhanced survival of lethally irradiated adenosine A3 receptor knockout mice. A role for hematopoietic growth factors? by Hofer, Michal, Pospíšil, Milan, Dušek, Ladislav, Hoferová, Zuzana, Komůrková, Denisa

“…Adenosine A 3 receptor knockout (A 3 AR KO) mice and their wild-type (WT) counterparts were compared from the point of view of their abilities to survive…”
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Agonist of the adenosine A^sub 3^ receptor, IB-MECA, and inhibitor of cyclooxygenase-2, meloxicam, given alone or in a combination early after total body irradiation enhance survival of [gamma]-irradiated mice by Hofer, Michal, Pospísil, Milan, Dusek, Ladislav, Hoferová, Zuzana, Komrková, Denisa

“…There exists a requirement for drugs which would be useful in therapy of an acute radiation damage of a mammalian organism. The aim of the study was to…”
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