Search Results - "Hofer, Silvia"

Appraisal of the Karnofsky Performance Status and proposal of a simple algorithmic system for its evaluation by Péus, Dominik, Newcomb, Nicolas, Hofer, Silvia

“…For over 60 years, the Karnofsky Performance Status (KPS) has proven itself a valuable tool with which to perform measurement of and comparison between the…”
Get full text

A specific miRNA signature in the peripheral blood of glioblastoma patients by Roth, Patrick, Wischhusen, Jörg, Happold, Caroline, Chandran, P. Anoop, Hofer, Silvia, Eisele, Günter, Weller, Michael, Keller, Andreas

“…J. Neurochem. (2011) 118, 449–457. The prognosis of patients afflicted by glioblastoma remains poor. Biomarkers for the disease would be desirable in order to…”
Get full text

High‐throughput proteomic analysis of FFPE tissue samples facilitates tumor stratification by Zhu, Yi, Weiss, Tobias, Zhang, Qiushi, Sun, Rui, Wang, Bo, Yi, Xiao, Wu, Zhicheng, Gao, Huanhuan, Cai, Xue, Ruan, Guan, Zhu, Tiansheng, Xu, Chao, Lou, Sai, Yu, Xiaoyan, Gillet, Ludovic, Blattmann, Peter, Saba, Karim, Fankhauser, Christian D., Schmid, Michael B., Rutishauser, Dorothea, Ljubicic, Jelena, Christiansen, Ailsa, Fritz, Christine, Rupp, Niels J., Poyet, Cedric, Rushing, Elisabeth, Weller, Michael, Roth, Patrick, Haralambieva, Eugenia, Hofer, Silvia, Chen, Chen, Jochum, Wolfram, Gao, Xiaofei, Teng, Xiaodong, Chen, Lirong, Zhong, Qing, Wild, Peter J., Aebersold, Ruedi, Guo, Tiannan

“…Formalin‐fixed, paraffin‐embedded (FFPE), biobanked tissue samples offer an invaluable resource for clinical and biomarker research. Here, we developed a…”
Get full text

MGMT methylation pattern of long-term and short-term survivors of glioblastoma reveals CpGs of the enhancer region to be of high prognostic value by Leske, Henning, Camenisch Gross, Ulrike, Hofer, Silvia, Neidert, Marian Christoph, Leske, Sabine, Weller, Michael, Lehnick, Dirk, Rushing, Elisabeth Jane

“…Abstract Treatment with the alkylating agent temozolomide is known to be prognostically beneficial in a subset of glioblastoma patients. Response to such…”
Get full text

A contemporary perspective on the diagnosis and treatment of diffuse gliomas in adults by Roth, Patrick, Hottinger, Andreas F., Hundsberger, Thomas, Läubli, Heinz, Schucht, Philippe, Reinert, Michael, Mamot, Christoph, Roelcke, Ulrich, Pesce, Gianfranco, Hofer, Silvia, Weller, Michael

“…Gliomas are intrinsic brain tumours, which are classified by the World Health Organization (WHO) into different grades of malignancy, with glioblastoma being…”
Get full text

Metastatic mesenchymal chondrosarcoma showing a sustained response to cabozantinib: A case report by Blum, Veronika, Andrei, Vanghelita, Ameline, Baptiste, Hofer, Silvia, Fuchs, Bruno, Strobel, Klaus, Allemann, Anna, Bode, Beata, Baumhoer, Daniel

“…Mesenchymal chondrosarcoma is a rare and aggressive sarcoma subtype with high risk for distant metastases and poor prognosis. Currently NCCN- and…”
Get full text

Molecular and Clinicopathologic Heterogeneity of Intracranial Tumors Mimicking Extraskeletal Myxoid Chondrosarcoma by Velz, Julia, Agaimy, Abbas, Frontzek, Karl, Neidert, Marian Christoph, Bozinov, Oliver, Wagner, Ulrich, Fritz, Christine, Coras, Roland, Hofer, Silvia, Bode-Lesniewska, Beata, Rushing, Elisabeth

“…Abstract Primary intracranial neoplasms with features of extraskeletal myxoid chondrosarcomas (EMC) are extremely rare and poorly characterized tumors with…”
Get full text

Intrathecal trastuzumab versus alternate routes of delivery for HER2-targeted therapies in patients with HER2+ breast cancer leptomeningeal metastases by Lazaratos, Anna-Maria, Maritan, Sarah M., Quaiattini, Andrea, Darlix, Amelie, Ratosa, Ivica, Ferraro, Emanuela, Griguolo, Gaia, Guarneri, Valentina, Pellerino, Alessia, Hofer, Silvia, Jacot, William, Stemmler, Hans-Joachim, van den Broek, Marcel P.H., Dobnikar, Nika, Panet, Francois, Lahijanian, Zubin, Morikawa, Aki, Seidman, Andrew D., Soffietti, Riccardo, Panasci, Lawrence, Petrecca, Kevin, Rose, April A.N., Bouganim, Nathaniel, Dankner, Matthew

“…Patients with HER2+ breast cancer (BC) frequently develop leptomeningeal metastases (LM). While HER2-targeted therapies have demonstrated efficacy in the…”
Get full text

Early metabolic responses in temozolomide treated low-grade glioma patients by Wyss, Matthias, Hofer, Silvia, Bruehlmeier, Matthias, Hefti, Martin, Uhlmann, Catrina, Bärtschi, Esther, Buettner, Ulrich Wolf, Roelcke, Ulrich

“…Amino acid transport and protein synthesis are important steps of tumor growth. We investigated the time course of tumor metabolism in low-grade gliomas (LGG)…”
Get full text

Efficacy of Surgery and Further Treatment of Progressive Glioblastoma by Woernle, Christoph Michael, Péus, Dominik, Hofer, Silvia, Rushing, Elisabeth Jane, Held, Ulrike, Bozinov, Oliver, Krayenbühl, Niklaus, Weller, Michael, Regli, Luca

“…Background Treatment options for patients with glioblastoma at progression have remained controversial, and selection criteria for the appropriate type of…”
Get full text

Chemotherapy for intracranial ependymoma in adults by Gramatzki, Dorothee, Roth, Patrick, Felsberg, Jörg, Hofer, Silvia, Rushing, Elisabeth J, Hentschel, Bettina, Westphal, Manfred, Krex, Dietmar, Simon, Matthias, Schnell, Oliver, Wick, Wolfgang, Reifenberger, Guido, Weller, Michael

“…Ependymal tumors in adults are rare, accounting for less than 4% of primary tumors of the central nervous system in this age group. The low prevalence of…”
Get full text

Fitness-to-drive for glioblastoma patients by Silvia Hofer, Kristina Keller, Lukas Imbach, Ulrich Roelcke, Gregor Hutter, Thomas Hundsberger, Caroline Hertler, Emilie Le Rhun, Flavio Vasella, Dominik Cordier, Marian Neidert, Andreas Hottinger, Denis Migliorini, Tobias Pflugshaupt, Noemi Eggenberger, Brigitta Baumert, Heinz Läubli, Dorothee Gramatzki, Michael Reinert, Gianfranco Pesce, Philippe Schucht, Irene Frank, Dirk Lehnick, Tobias Weiss, Hans-Georg Wirsching, Fabian Wolpert, Patrick Roth, Michael Weller

“…OBJECTIVE The management of brain tumour patients who would like to resume driving is complex, and needs multidisciplinary input and a consensus among treating…”
Get full text

Spondylectomy in the treatment of neoplastic spinal lesions - A retrospective outcome analysis of 582 patients using a patient-level meta-analysis by Spiessberger, Alexander, Dietz, Nicholas, Arvind, Varun, Nasim, Mansoor, Gruter, Basil, Nevzati, Edin, Hofer, Silvia, Cho, Samuel

“…This study aims at identifying predictors of postoperative complications, lesion recurrence, and overall survival in patients undergoing en bloc spondylectomy…”
Get full text

Fitness-to-drive for glioblastoma patients: Guidance from the Swiss Neuro-Oncology Society (SwissNOS) and the Swiss Society for Legal Medicine (SGRM) by Hofer, Silvia, Keller, Kristina, Imbach, Lukas, Roelcke, Ulrich, Hutter, Gregor, Thomas, Hundsberger, Hertler, Caroline, Le Rhun, Emilie, Vasella, Flavio, Cordier, Dominik, Neidert, Marian, Hottinger, Andreas, Migliorini, Denis, Pflugshaupt, Tobias, Eggenberger, Noemi, Baumert, Brigitta, Läubli, Heinz, Gramatzki, Dorothee, Reinert, Michael, Pesce, Gianfranco, Schucht, Philippe, Frank, Irène, Lehnick, Dirk, Weiss, Tobias, Hans-Georg, Wirsching, Wolpert, Fabian, Roth, Patrick, Weller, Michael

“…The management of brain tumour patients who would like to resume driving is complex, and needs multidisciplinary input and a consensus among treating…”
Get full text

Local Targeting of Malignant Gliomas by the Diffusible Peptidic Vector 1,4,7,10-Tetraazacyclododecane-1-Glutaric Acid-4,7,10-Triacetic Acid-Substance P by KNEIFEL, Stefan, CORDIER, Dominik, ARNOLD, Marlene, MUELLER-BRAND, Jan, MAECKE, Helmut R, REUBI, Jean Claude, MERLO, Adrian, GOOD, Stephan, IONESCU, Mihai C. S, GHAFFARI, Anthony, HOFER, Silvia, KRETZSCHMAR, Martin, TOLNAY, Markus, APOSTOLIDIS, Christos, WASER, Beatrice

“…Purpose: Malignant glial brain tumors consistently overexpress neurokinin type 1 receptors. In classic seed-based brachytherapy, one to several rigid 125 I…”
Get full text

P1122: A PROSPECTIVE, NON‐INTERVENTIONAL STUDY OF REAL‐WORLD TREATMENT AND OUTCOME IN SECONDARY CNS LYMPHOMA by Habringer, Stefan, Demel, Uta, Fietz, Anne‐Katrin, Lammer, Felicitas, Schroers, Roland, Hofer, Silvia, Bairey, Osnat, Braess, Jan, Sofia Meier‐Stiegen, Anna, Stuhlmann, Reingard, Schmidt‐Hieber, Martin, Hoffmann, Johannes, Zinngrebe, Bettina, Kaiser, Ulrich, Reimer, Peter, Möhle, Robert, Fix, Peter, Höffkes, Heinz‐Gert, Langenkamp, Ulrich, Büschenfelde, Christian Meyer Zum, Hopfer, Olaf, Stoltefuß, Andrea, La Rosée, Paul, Blasberg, Henning, Jordan, Karin, Kaun, Stephan, Unteroberdörster, Meike, Brünneck, Ann‐Christin, Capper, David, Heppner, Frank L., Chapuy, Björn, Janz, Martin, Schwartz, Stefan, Konietschke, Frank, Vajkoczy, Peter, Korfel, Agnieszka, Keller, Ulrich

Get full text

Patupilone (epothilone B) for recurrent glioblastoma: clinical outcome and translational analysis of a single-institution phase I/II trial by Oehler, Christoph, Frei, Karl, Rushing, Elisabeth J, McSheehy, Paul M J, Weber, Dirk, Allegrini, Peter R, Weniger, Dorothea, Lütolf, Urs M, Knuth, Alexander, Yonekawa, Yasuhiro, Barath, Krisztina, Broggini-Tenzer, Angela, Pruschy, Martin, Hofer, Silvia

“…Patients with glioblastoma (GBM) inevitably develop recurrent or progressive disease after initial multimodal treatment and have a median survival of 6-9…”
Get more information

Role of arterial hypertension as a predictive marker for bevacizumab efficacy in recurrent glioblastoma - a prospective analysis by Wagner, Claudia C, Held, Ulrike, Kofmehl, Reto, Battegay, Edouard, Zimmerli, Lukas, Hofer, Silvia

Get more information

Outcome and prognostic factors in cerebellar glioblastoma multiforme in adults: a retrospective study from the Rare Cancer Network by Weber, Damien C, Miller, Robert C, Villà, Salvador, Hanssens, Patrick, Baumert, Brigitta G, Castadot, Pierre, Varlet, Pascale, Abacioglu, Ufuk, Igdem, Sefik, Szutowicz, Ewa, Nishioka, Hiroshi, Hofer, Silvia, Rutz, Hans Peter, Ozsahin, Mahmut, Taghian, Alphonse, Mirimanoff, René O

“…The aim of this study was to assess the outcome in patients with cerebellar glioblastoma (GBM) treated in 15 institutions of the Rare Cancer Network. Data from…”
Get more information

Gefitinib accumulation in glioblastoma tissue by Hofer, Silvia, Frei, Karl, Rutz, Hans Peter

“…Therapeutic agents for brain tumors confront multiple physical and metabolic hurdles. These include the blood brain barrier (BBB), vascular and interstitial…”
Get full text