Search Results - "Hofer, Matthias D."

Rapid adoption of penoscrotal decompression for ischemic priapism in private practice by Akula, Kole P., Hofer, Matthias D.

“…Refractory ischemic priapism is a difficult to treat clinical entity for which there are a host of shunt procedures identified, but no singular agreed upon…”
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Treatment-Dependent Androgen Receptor Mutations in Prostate Cancer Exploit Multiple Mechanisms to Evade Therapy by STEINKAMP, Mara P, O'MAHONY, Orla A, PIENTA, Kenneth J, ROBINS, Diane M, BROGLEY, Michele, REHMAN, Haniya, LAPENSEE, Elizabeth W, DHANASEKARAN, Saravana, HOFER, Matthias D, KUEFER, Rainer, CHINNAIYAN, Arul, RUBIN, Mark A

“…Mutations in the androgen receptor (AR) that enable activation by antiandrogens occur in hormone-refractory prostate cancer, suggesting that mutant ARs are…”
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Prostate-specific membrane antigen expression as a predictor of prostate cancer progression by Perner, Sven, MD, Hofer, Matthias D., MD, Kim, Robert, Shah, Rajal B., MD, Li, Haojie, MD, PhD, Möller, Peter, MD, Hautmann, Richard E., MD, Gschwend, Juergen E., MD, Kuefer, Rainer, MD, Rubin, Mark A., MD

“…Summary Distinguishing aggressive prostate cancer from indolent disease represents an important clinical challenge, because current therapy may lead to…”
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Characterization of TMPRSS2-ERG Fusion High-Grade Prostatic Intraepithelial Neoplasia and Potential Clinical Implications by MOSQUERA, Juan-Miguel, PERNER, Sven, SHAH, Rajal B, LODA, Massimo, RUBIN, Mark A, GENEGA, Elizabeth M, SANDA, Martin, HOFER, Matthias D, MERTZ, Kirsten D, PARIS, Pamela L, SIMKO, Jeff, BISMAR, Tarek A, AYALA, Gustavo

“…Purpose: More than 1,300,000 prostate needle biopsies are done annually in the United States with up to 16% incidence of isolated high-grade prostatic…”
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Editorial Comment to Does mechanical bowel preparation ameliorate damage from rectal injury in radical prostatectomy? Analysis of 151 rectal injury cases by Hofer, Matthias D

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Current Concepts in Infections Associated with Penile Prostheses and Artificial Sphincters by Hofer, Matthias D., MD, Gonzalez, Chris M., MD

“…Implantation of penile prostheses and artificial urinary sphincters have gained widespread acceptance for the treatment of refractory erectile dysfunction and…”
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Treatment of Radiation-Induced Urethral Strictures by Hofer, Matthias D., MD, Liu, Joceline S., MD, Morey, Allen F., MD

“…Radiation therapy may result in urethral strictures from vascular damage. Most radiation-induced urethral strictures occur in the bulbomembranous junction, and…”
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Risk of urethral stricture recurrence increases over time after urethroplasty by Han, Justin S, Liu, Joceline, Hofer, Matthias D, Fuchs, Amanda, Chi, Amanda, Stein, Daniel, Dielubanza, Elodi, Ballek, Nathaniel, Gonzalez, Chris M

“…Objective To report a single institutional experience with urethroplasty outcomes and success rates at long‐term follow up. Methods A retrospective review was…”
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Elevated E2F1 inhibits transcription of the androgen receptor in metastatic hormone-resistant prostate cancer by DAVIS, Joanne N, WOJNO, Kirk J, DAIGNAULT, Stephanie, HOFER, Matthias D, KUEFER, Rainer, RUBIN, Mark A, DAY, Mark L

“…Activation of E2F transcription factors, through disruption of the retinoblastoma (Rb) tumor-suppressor gene, is a key event in the development of many human…”
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Predisposition for TMPRSS2-ERG Fusion in Prostate Cancer by Variants in DNA Repair Genes by LUEDEKE, Manuel, LINNERT, Carmen M, HOFER, Matthias D, SUROWY, Harald M, RINCKLEB, Antje E, HOEGEL, Josef, KUEFER, Rainer, RUBIN, Mark A, VOGEL, Walther, MAIER, Christiane

“…The somatic fusion of TMPRSS2 to ETS oncogenes is a common event in prostate cancer (PCa). We hypothesized that defects in DNA repair may lead to an increase…”
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RHAMM (CD168) Is Overexpressed at the Protein Level and May Constitute an Immunogenic Antigen in Advanced Prostate Cancer Disease by Gust, Kilian M., Hofer, Matthias D., Perner, Sven R., Kim, Robert, Chinnaiyan, Arul M., Varambally, Sooryanarayana, Moller, Peter, Rinnab, Ludwig, Rubin, Mark A., Greiner, Jochen, Schmitt, Michael, Kuefer, Rainer, Ringhoffer, Mark

“…Localized prostate cancer (CaP) can be cured using several strategies. However, the need to identify active substances in advanced tumor stages is tremendous,…”
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Inferring loss-of-heterozygosity from unpaired tumors using high-density oligonucleotide SNP arrays by Beroukhim, Rameen, Lin, Ming, Park, Yuhyun, Hao, Ke, Zhao, Xiaojun, Garraway, Levi A, Fox, Edward A, Hochberg, Ephraim P, Mellinghoff, Ingo K, Hofer, Matthias D, Descazeaud, Aurelien, Rubin, Mark A, Meyerson, Matthew, Wong, Wing Hung, Sellers, William R, Li, Cheng

“…Loss of heterozygosity (LOH) of chromosomal regions bearing tumor suppressors is a key event in the evolution of epithelial and mesenchymal tumors…”
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Overexpression, amplification, and androgen regulation of TPD52 in prostate cancer by RUBIN, Mark A, VARAMBALLY, Sooryanarayana, HSI, Bae-Li, BYRNE, Jennifier A, PIENTA, Kenneth J, COLLINS, Colin, SELLERS, William R, CHINNAIYAN, Arul M, BEROUKHIM, Rameen, TOMLINS, Scott A, RHODES, Daniel R, PARIS, Pamela L, HOFER, Matthias D, STORZ-SCHWEIZER, Martina, KUEFER, Rainer, FLETCHER, Jonathan A

“…Gains in the long arm of chromosome 8 (8q) are believed to be associated with poor outcome and the development of hormone-refractory prostate cancer. Based on…”
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Defining Aggressive Prostate Cancer Using a 12-Gene Model by Bismar, Tarek A., Demichelis, Francesca, Riva, Alberto, Kim, Robert, Varambally, Sooryanarayana, He, Le, Kutok, Jeff, Aster, Jonathan C., Tang, Jeffery, Kuefer, Rainer, Hofer, Matthias D., Febbo, Phillip G., Chinnaiyan, Arul M., Rubin, Mark A.

“…The critical clinical question in prostate cancer research is: How do we develop means of distinguishing aggressive disease from indolent disease? Using a…”
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Spiral array: a new high-throughput technology covers tissue heterogeneity by Fukuoka, Junya, Hofer, Matthias D, Hori, Takashi, Tanaka, Tomonori, Ishizawa, Shin, Nomoto, Kazuhiro, Saito, Manami, Uemura, Takeshi, Chirieac, Lucian R

“…Tissue array is a well-established technique that connects basic research with clinical applications and allows for the validation of many pathobiologic events…”
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The role of metastasis-associated protein 1 in prostate cancer progression by HOFER, Matthias D, KUEFER, Rainer, MENKE, Andre, CHINNAIYAN, Arul M, RUBIN, Mark A, VARAMBALLY, Sooryanarayana, HAOJIE LI, JING MA, SHAPIRO, Geoffrey I, GSCHWEND, Juergen E, HAUTMANN, Richard E, SANDA, Martin G, GIEHL, Klaudia

“…Distinguishing aggressive prostate cancer from indolent disease represents an important clinical challenge, as current therapy requires over treating men with…”
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Lobaplatin inhibits prostate cancer progression in part by impairing AR and ERG signal by Hofer, Matthias D.

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The sexual impact of androgenic anabolic steroid abuse an understudied phenomena by Akula, Kole P, McBeth, Lucien R, Hofer, Matthias D

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Urologic Emergencies by Manjunath, Adarsh S., Hofer, Matthias D.

“…Urologic emergencies can involve the kidneys, ureters, bladder, urethra, penis, scrotum, or testicles. History and physical examination are essential to…”
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Collagen XXIII Expression Is Associated with Prostate Cancer Recurrence and Distant Metastases by BANYARD, Jacqueline, BAO, Lere, HOFER, Matthias D, ZURAKOWSKI, David, SPIVEY, Kristin A, FELDMAN, Adam S, HUTCHINSON, Lloyd M, KUEFER, Rainer, RUBIN, Mark A, ZETTER, Bruce R

“…Purpose: We had previously identified a new transmembrane collagen, type XXIII, in metastatic rat prostate carcinoma cells. The purpose of this study was to…”
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