Search Results - "Hofels, Susanne"

Unipolar depression and hippocampal volume: Impact of DNA sequence variants of the glucocorticoid receptor gene by Zobel, Astrid, Jessen, Frank, von Widdern, Olrik, Schuhmacher, Anna, Höfels, Susanne, Metten, Martin, Rietschel, Marcella, Scheef, Lukas, Block, Wolfgang, Becker, Tim, Schild, Hans H., Maier, Wolfgang, Schwab, Sibylle G.

“…Glucocorticoid receptor (GR) plays a major role in regulation of the hypothalamic–pituitary–adrenocortical (HPA) system; HPA dysregulation represents the most…”
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Association of amygdala volumes with cortisol secretion in unipolar depressed patients by Schuhmacher, Anna, Mössner, Rainald, Jessen, Frank, Scheef, Lukas, Block, Wolfgang, Belloche, Anna Christine, Lennertz, Leonhard, Welper, Hanne, Höfels, Susanne, Pfeiffer, Ute, Wagner, Michael, Maier, Wolfgang, Schwab, Sybille, Zobel, Astrid

“…Abstract Major depressive disorder (MDD) is accompanied by morphological changes of brain structures which are of great importance in the neural circuitry…”
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Association of major depression with rare functional variants in norepinephrine transporter and serotonin1A receptor genes by Haenisch, Britta, Linsel, Karoline, Brüss, Michael, Gilsbach, Ralf, Propping, Peter, Nöthen, Markus M., Rietschel, Marcella, Fimmers, Rolf, Maier, Wolfgang, Zobel, Astrid, Höfels, Susanne, Guttenthaler, Vera, Göthert, Manfred, Bönisch, Heinz

“…Dysregulations of central noradrenergic and serotonergic neurotransmission have been suggested to contribute to the pathogenesis of neuropsychiatric disorders…”
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Reduced cardio-respiratory coupling after treatment with nortriptyline in contrast to S-citalopram by Bär, Karl-Jürgen, Schuhmacher, Anna, Höfels, Susanne, Schulz, Steffen, Voss, Andreas, Yeragani, Vikram K, Maier, Wolfgang, Zobel, Astrid

“…Abstract Objective Major depressive disorder is associated with increased cardiac mortality. A decrease in vagal modulation related to reduced heart rate…”
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The influence of age, gender and socio-economic status on multimorbidity patterns in primary care. First results from the multicare cohort study by Schäfer, Ingmar, Hansen, Heike, Schön, Gerhard, Höfels, Susanne, Altiner, Attila, Dahlhaus, Anne, Gensichen, Jochen, Riedel-Heller, Steffi, Weyerer, Siegfried, Blank, Wolfgang A, König, Hans-Helmut, von dem Knesebeck, Olaf, Wegscheider, Karl, Scherer, Martin, van den Bussche, Hendrik, Wiese, Birgitt

“…Multimorbidity is a phenomenon with high burden and high prevalence in the elderly. Our previous research has shown that multimorbidity can be divided into the…”
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Evidence for a Relationship Between Genetic Variants at the Brain-Derived Neurotrophic Factor (BDNF) Locus and Major Depression by Schumacher, Johannes, Jamra, Rami Abou, Becker, Tim, Ohlraun, Stephanie, Klopp, Norman, Binder, Elisabeth B., Schulze, Thomas G., Deschner, Monika, Schmäl, Christine, Höfels, Susanne, Zobel, Astrid, Illig, Thomas, Propping, Peter, Holsboer, Florian, Rietschel, Marcella, Nöthen, Markus M., Cichon, Sven

“…Previous genetic studies investigating a possible involvement of variations at the brain derived neurotrophic factor (BDNF) gene locus in major depressive…”
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The German MultiCare-study: Patterns of multimorbidity in primary health care - protocol of a prospective cohort study by Schäfer, Ingmar, Hansen, Heike, Schön, Gerhard, Maier, Wolfgang, Höfels, Susanne, Altiner, Attila, Fuchs, Angela, Gerlach, Ferdinand M, Petersen, Juliana J, Gensichen, Jochen, Schulz, Sven, Riedel-Heller, Steffi, Luppa, Melanie, Weyerer, Siegfried, Werle, Jochen, Bickel, Horst, Barth, Kerstin, König, Hans-Helmut, Rudolph, Anja, Wiese, Birgitt, Prokein, Jana, Bullinger, Monika, von dem Knesebeck, Olaf, Eisele, Marion, Kaduszkiewicz, Hanna, Wegscheider, Karl, van den Bussche, Hendrik

“…Multimorbidity is a highly frequent condition in older people, but well designed longitudinal studies on the impact of multimorbidity on patients and the…”
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The power of sample size and homogenous sampling: Association between the 5-HTTLPR serotonin transporter polymorphism and major depressive disorder by Hoefgen, Barbara, Schulze, Thomas G., Ohlraun, Stephanie, von Widdern, Olrik, Höfels, Susanne, Gross, Magdalena, Heidmann, Vivien, Kovalenko, Svetlana, Eckermann, Anita, Kölsch, Heike, Metten, Martin, Zobel, Astrid, Becker, Tim, Nöthen, Markus M., Propping, Peter, Heun, Reinhard, Maier, Wolfgang, Rietschel, Marcella

“…Several lines of evidence indicate that abnormalities in the functioning of the central serotonergic system are involved in the pathogenesis of affective…”
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Social inequalities in patient-reported outcomes among older multimorbid patients--results of the MultiCare cohort study by von dem Knesebeck, Olaf, Bickel, Horst, Fuchs, Angela, Gensichen, Jochen, Höfels, Susanne, Riedel-Heller, Steffi G, König, Hans-Helmut, Mergenthal, Karola, Schön, Gerhard, Wegscheider, Karl, Weyerer, Siegfried, Wiese, Birgitt, Scherer, Martin, van den Bussche, Hendrik, Schäfer, Ingmar

“…In this article three research questions are addressed: (1) Is there an association between socioeconomic status (SES) and patient-reported outcomes in a…”
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No association of the Val66Met polymorphism of the brain-derived neurotrophic factor with hippocampal volume in major depression by Jessen, Frank, Schuhmacher, Anna, von Widdern, Ole, Guttenthaler, Vera, Hofels, Susanne, Suliman, Husam, Scheef, Lukas, Block, Wolfgang, Urbach, Horst, Maier, Wolfgang, Zobel, Astrid

“…Recently, an association of the Val66Met polymorphism of the brain-derived neurotrophic factor with hippocampal volume in patients with major depression has…”
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Relative impact of multimorbid chronic conditions on health-related quality of life--results from the MultiCare Cohort Study by Brettschneider, Christian, Leicht, Hanna, Bickel, Horst, Dahlhaus, Anne, Fuchs, Angela, Gensichen, Jochen, Maier, Wolfgang, Riedel-Heller, Steffi, Schäfer, Ingmar, Schön, Gerhard, Weyerer, Siegfried, Wiese, Birgitt, van den Bussche, Hendrik, Scherer, Martin, König, Hans-Helmut

“…Multimorbidity has a negative impact on health-related quality of life (HRQL). Previous studies included only a limited number of conditions. In this study, we…”
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A variant of the neuronal amino acid transporter SLC6A15 is associated with ACTH and cortisol responses and cognitive performance in unipolar depression by Schuhmacher, Anna, Lennertz, Leonhard, Wagner, Michael, Höfels, Susanne, Pfeiffer, Ute, Guttenthaler, Vera, Maier, Wolfgang, Zobel, Astrid, Mössner, Rainald

“…Major depressive disorder (MDD) is accompanied by both cognitive impairments and a hyperactivity of the hypothalamic–pituitary–adrenocortical (HPA) system,…”
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DNA sequence variants of the FKBP5 gene are associated with unipolar depression by Zobel, Astrid, Schuhmacher, Anna, Jessen, Frank, Höfels, Susanne, von Widdern, Olrik, Metten, Martin, Pfeiffer, Ute, Hanses, Claudia, Becker, Tim, Rietschel, Marcella, Scheef, Lukas, Block, Wolfgang, Schild, Hans H., Maier, Wolfgang, Schwab, Sibylle G.

“…FKBP5 is a glucocorticoid receptor-regulating co-chaperone of hsp-90 and, therefore, is suggested to play a role in the regulation of the…”
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A comparative study demonstrated that prevalence figures on multimorbidity require cautious interpretation when drawn from a single database by van den Bussche, Hendrik, Schäfer, Ingmar, Wiese, Birgitt, Dahlhaus, Anne, Fuchs, Angela, Gensichen, Jochen, Höfels, Susanne, Hansen, Heike, Leicht, Hanna, Koller, Daniela, Luppa, Melanie, Nützel, Anna, Werle, Jochen, Scherer, Martin, Wegscheider, Karl, Glaeske, Gerd, Schön, Gerhard

“…Abstract Objective We investigated the degree of comparability of the prevalence of chronic diseases and disease combinations in the elderly in two databases…”
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Antiplatelet effects of antidepressant treatment: A randomized comparison between escitalopram and nortriptyline by Flöck, Anne, Zobel, Astrid, Bauriedel, Gerhard, Tuleta, Izabela, Hammerstingl, Christoph, Höfels, Susanne, Schuhmacher, Anna, Maier, Wolfgang, Nickenig, Georg, Skowasch, Dirk

“…Abstract Introduction Depressive disorders have been identified as independent risk factors for coronary heart disease. The present study (i) compared platelet…”
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G72 and Its Association With Major Depression and Neuroticism in Large Population-Based Groups From Germany by Rietschel, Marcella, Beckmann, Lars, Strohmaier, Jana, Georgi, Alexander, Karpushova, Anna, Schirmbeck, Frederike, Boesshenz, Katja V., Schmäl, Christine, Bürger, Christin, Jamra, Rami Abou, Schumacher, Johannes, Höfels, Susanne, Kumsta, Robert, Entringer, Sonja, Krug, Axel, Markov, Valentin, Maier, Wolfgang, Propping, Peter, Wüst, Stefan, Kircher, Tilo, Nöthen, Markus M., Cichon, Sven, Schulze, Thomas G.

“…Objective: G72 is among the most frequently replicated vulnerability genes for schizophrenia and bipolar disorder. The authors previously found identical…”
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The functional coding variant Asn107Ile of the neuropeptide S receptor gene (NPSR1) is associated with schizophrenia and modulates verbal memory and the acoustic startle response by Lennertz, Leonhard, Quednow, Boris B., Schuhmacher, Anna, Petrovsky, Nadine, Frommann, Ingo, Schulze-Rauschenbach, Svenja, Landsberg, Martin W., Steinbrecher, Anja, Höfels, Susanne, Pukrop, Ralf, Klosterkötter, Joachim, Franke, Petra E., Wölwer, Wolfgang, Gaebel, Wolfgang, Häfner, Heinz, Maier, Wolfgang, Wagner, Michael, Mössner, Rainald

“…Recently, the neuropeptide S (NPS) neurotransmitter system has been identified as a promising psychopharmacological drug target given that NPS has shown…”
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Possible association between genetic variants at the GRIN1 gene and schizophrenia with lifetime history of depressive symptoms in a German sample by Georgi, Alexander, Jamra, Rami Abou, Klein, Katrin, Villela, Angela Wolf, Schumacher, Johannes, Becker, Tim, Paul, Torsten, Schmael, Christine, Höfels, Susanne, Klopp, Norman, Illig, Thomas, Propping, Peter, Cichon, Sven, Nöthen, Markus M, Schulze, Thomas G, Rietschel, Marcella

“…Genetic variation in glutamatergic signalling pathways is believed to play a substantial role in the aetiology of schizophrenia. The N-methyl-D-aspartate…”
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Association of major depression with rare functional variants in norepinephrine transporter and serotonin 1A receptor genes by Haenisch, Britta, Linsel, Karoline, Brüss, Michael, Gilsbach, Ralf, Propping, Peter, Nöthen, Markus M., Rietschel, Marcella, Fimmers, Rolf, Maier, Wolfgang, Zobel, Astrid, Höfels, Susanne, Guttenthaler, Vera, Göthert, Manfred, Bönisch, Heinz

“…Abstract Dysregulations of central noradrenergic and serotonergic neurotransmission have been suggested to contribute to the pathogenesis of neuropsychiatric…”
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Agreement between self-reported and general practitioner-reported chronic conditions among multimorbid patients in primary care - results of the MultiCare Cohort Study by Hansen, Heike, Schäfer, Ingmar, Schön, Gerhard, Riedel-Heller, Steffi, Gensichen, Jochen, Weyerer, Siegfried, Petersen, Juliana J, König, Hans-Helmut, Bickel, Horst, Fuchs, Angela, Höfels, Susanne, Wiese, Birgitt, Wegscheider, Karl, van den Bussche, Hendrik, Scherer, Martin

“…Multimorbidity is a common phenomenon in primary care. Until now, no clinical guidelines for multimorbidity exist. For the development of these guidelines, it…”
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