Search Results - "Hoet, Peter H. M"

Noninvasive and Invasive Pulmonary Function in Mouse Models of Obstructive and Restrictive Respiratory Diseases by Vanoirbeek, Jeroen A. J, Rinaldi, Manuela, De Vooght, Vanessa, Haenen, Steven, Bobic, Sonja, Gayan-Ramirez, Ghislaine, Hoet, Peter H. M, Verbeken, Erik, Decramer, Marc, Nemery, Benoit, Janssens, Wim

“…Pulmonary function analysis is an important tool in the evaluation of mouse respiratory disease models, but much controversy still exists on the validity of…”
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Associations between occupational and environmental exposures and organ involvement in sarcoidosis: a retrospective case-case analysis by Ronsmans, Steven, De Ridder, Jolien, Vandebroek, Eline, Keirsbilck, Stephan, Nemery, Benoit, Hoet, Peter H M, Vanderschueren, Steven, Wuyts, Wim A, Yserbyt, Jonas

“…Sarcoidosis most commonly affects lungs and intrathoracic lymph nodes, but any other organ can be involved. In epidemiological studies, many occupational and…”
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Exposure to silicates and systemic autoimmune-related outcomes in rodents: a systematic review by Janssen, Lisa M F, Ghosh, Manosij, Lemaire, Frauke, Michael Pollard, K, Hoet, Peter H M

“…Autoimmunity can result from the interplay between genetic background and effects of environmental and/or occupational exposure to hazardous materials. Several…”
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Toluene diisocyanate and methylene diphenyl diisocyanate: asthmatic response and cross-reactivity in a mouse model by Pollaris, Lore, Devos, Fien, De Vooght, Vanessa, Seys, Sven, Nemery, Benoit, Hoet, Peter H. M., Vanoirbeek, Jeroen A. J.

“…Both 2,4-toluene diisocyanate (TDI) and 4,4-methylene diphenyl diisocyanate (MDI) can cause occupational asthma. In this study, we optimized our mouse model of…”
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IL-13 is a central mediator of chemical-induced airway hyperreactivity in mice by Devos, Fien C, Pollaris, Lore, Cremer, Jonathan, Seys, Sven, Hoshino, Tomoaki, Ceuppens, Jan, Talavera, Karel, Nemery, Benoit, Hoet, Peter H M, Vanoirbeek, Jeroen A J

“…While the importance of the Th2 cytokine IL-13 as a central mediator of airway hyperreactivity (AHR) has been described in allergic protein-induced asthma,…”
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Choice of mouse strain influences the outcome in a mouse model of chemical-induced asthma by De Vooght, Vanessa, Vanoirbeek, Jeroen A J, Luyts, Katrien, Haenen, Steven, Nemery, Benoit, Hoet, Peter H M

“…The development of occupational asthma is the result of interactions between environmental factors and individual susceptibility. We assessed how our model of…”
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Impact of a Polymer-Based Nanoparticle with Formoterol Drug as Nanocarrier System In Vitro and in an Experimental Asthmatic Model by Bakan, Buket, Jonckheere, Anne-Charlotte, Decaesteker, Tatjana, Marain, Nora F, Murugadoss, Sivakumar, Karabay Yavasoglu, Nefise Ulku, Şahar, Umut, Şenay, Raziye Hilal, Akgöl, Sinan, Göksel, Özlem, Hoet, Peter H M, Vanoirbeek, Jeroen A J

“…The implementation of nanotechnology in pulmonary delivery systems might result in better and more specific therapy. Therefore, a nano-sized drug carrier…”
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Cytokine production by co-cultures exposed to monodisperse amorphous silica nanoparticles: The role of size and surface area by Napierska, Dorota, Thomassen, Leen C.J., Vanaudenaerde, Bart, Luyts, Katrien, Lison, Dominique, Martens, Johan A., Nemery, Benoit, Hoet, Peter H.M.

“…[Display omitted] ► Size and surface area of silica nanoparticles have influence on cytokine secretion. ► The smallest nanoparticles induce the most pronounced…”
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Proteomic Alterations in B Lymphocytes of Sensitized Mice in a Model of Chemical-Induced Asthma by Haenen, Steven, Vanoirbeek, Jeroen A J, De Vooght, Vanessa, Schoofs, Liliane, Nemery, Benoit, Clynen, Elke, Hoet, Peter H M

“…The role of B-lymphocytes in chemical-induced asthma is largely unknown. Recent work demonstrated that transferring B lymphocytes from toluene diisocyanate…”
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Carbon Nanotube- and Asbestos-Induced DNA and RNA Methylation Changes in Bronchial Epithelial Cells by Emerce, Esra, Ghosh, Manosij, Öner, Deniz, Duca, Radu-Corneliu, Vanoirbeek, Jeroen, Bekaert, Bram, Hoet, Peter H. M, Godderis, Lode

“…Carbon nanotubes (CNTs) are nanoscale tube-shaped carbon materials used in many industrial areas. Their fiber shape has caused concerns about their toxicity…”
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How physico-chemical characteristics of nanoparticles cause their toxicity: complex and unresolved interrelations by Luyts, Katrien, Napierska, Dorota, Nemery, Ben, Hoet, Peter H M

“…The increased use of and interest in nanoparticles (NPs) have resulted in an enormous amount of NPs with different compositions and physico-chemical…”
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TRPV4 activation triggers protective responses to bacterial lipopolysaccharides in airway epithelial cells by Alpizar, Yeranddy A., Boonen, Brett, Sanchez, Alicia, Jung, Carole, López-Requena, Alejandro, Naert, Robbe, Steelant, Brecht, Luyts, Katrien, Plata, Cristina, De Vooght, Vanessa, Vanoirbeek, Jeroen A. J., Meseguer, Victor M., Voets, Thomas, Alvarez, Julio L., Hellings, Peter W., Hoet, Peter H. M., Nemery, Benoit, Valverde, Miguel A., Talavera, Karel

“…Lipopolysaccharides (LPS), the major components of the wall of gram-negative bacteria, trigger powerful defensive responses in the airways via mechanisms…”
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Development and validation of a human bronchial epithelial spheroid model to study respiratory toxicity in vitro by Celis, Thomas, Bullens, Dominique M. A., Hoet, Peter H. M., Ghosh, Manosij

“…The use of laboratory animals in research has been extensively criticized. While most of the critique has been centered around the ethical aspect, also the…”
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Neurotoxicity of four frequently used nanoparticles: a systematic review to reveal the missing data by Gong, Jia-You, Holt, Matthew G., Hoet, Peter H. M., Ghosh, Manosij

“…Systemic exposure to nanoparticles (NPs) adversely affects different organs, including the nervous system. We systematically extracted data from publication on…”
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Immunological determinants of ventilatory changes induced in mice by dermal sensitization and respiratory challenge with toluene diisocyanate by Tarkowski, Maciej, Vanoirbeek, Jeroen A J, Vanhooren, Hadewijch M, De Vooght, Vanessa, Mercier, Caroline M, Ceuppens, Jan, Nemery, Benoit, Hoet, Peter H M

“…The objective of the study was to characterize better the immunologic mechanisms underlying a previously developed animal model of chemical-induced asthma…”
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Nano-titanium dioxide modulates the dermal sensitization potency of DNCB by Hussain, Salik, Smulders, Stijn, De Vooght, Vanessa, Ectors, Bert, Boland, Sonja, Marano, Francelyne, Van Landuyt, Kirsten L, Nemery, Benoit, Hoet, Peter H M, Vanoirbeek, Jeroen A J

“…We determined the ability of a model nanoparticle (NP) (titanium dioxide, TiO(2)) to modulate sensitization induced by a known potent dermal sensitizer…”
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Toxicity of nanoparticles embedded in paints compared with pristine nanoparticles in mice by Smulders, Stijn, Luyts, Katrien, Brabants, Gert, Landuyt, Kirsten Van, Kirschhock, Christine, Smolders, Erik, Golanski, Luana, Vanoirbeek, Jeroen, Hoet, Peter H M

“…The unique physical and chemical properties of nanomaterials have led to their increased use in many industrial applications, including as a paint additive…”
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Assessment of Experimental Techniques That Facilitate Human Granuloma Formation in an In Vitro System: A Systematic Review by Ganesan, Nirosha, Ronsmans, Steven, Vanoirbeek, Jeroen, Hoet, Peter H M

“…The process of granuloma formation is complex, and due to species differences, the validity of animal studies is somewhat questioned. Moreover, the large…”
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How long do the systemic and ventilatory responses to toluene diisocyanate persist in dermally sensitized mice? by Vanoirbeek, Jeroen A.J., PhD, De Vooght, Vanessa, MSc, Vanhooren, Hadewijch M., MSc, Nawrot, Tim S., PhD, Nemery, Benoit, MD, PhD, Hoet, Peter H.M., PhD

“…Background Years after removal from exposure, workers with occupational asthma still show respiratory symptoms and airway hyperresponsiveness on re-exposure to…”
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Lung distribution, quantification, co-localization and speciation of silver nanoparticles after lung exposure in mice by Smulders, Stijn, Larue, Camille, Sarret, Geraldine, Castillo-Michel, Hiram, Vanoirbeek, Jeroen, Hoet, Peter H.M.

“…[Display omitted] •Local Ag distribution, and co-localization with Fe, Cu and S, was determined.•XRF, μXANES, and μPIXE techniques were used.•A quarter of all…”
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