Search Results - "Hoernquist, E"

Early perioperative immunological effects of anaesthesia and analgesia in patients undergoing prostate cancer surgery: A randomised pilot study by Fant, Federica, Tina, Elisabet, Andersson, Sven Olof, Magnuson, Anders, Hultgren-Hörnquist, Elisabeth, Gupta, Anil

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Cholera toxin adjuvant greatly promotes antigen priming of T cells by Hörnquist, E, Lycke, N

“…Cholera toxin (CT) given perorally is a powerful mucosal immunogen and adjuvant. Information that explains the adjuvant effect of CT may be used for the…”
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Dietary Antigen‐Specific T‐Cell Responses: Switch from an Interleukin‐10‐Dominated Response in Normal Mice to a T‐Helper 1 Cytokine Profile in Gαi2‐Deficient Mice prior to Colitis by Bjursten, M., Hultgren Hörnquist, E.

“…We investigated dietary antigen‐specific T‐cell responses in mesenteric lymph nodes (MLN) and Peyer's patches (PP) in noncolitic control mice as well as in…”
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Toll‐like Receptor Cross‐hyporesponsiveness is Functional in Interleukin‐1‐receptor‐associated Kinase‐1 (IRAK‐1)‐deficient Macrophages: Differential Role Played by IRAK‐1 in Regulation of Tumour Necrosis Factor and Interleukin‐10 Production by Berglund, M., Thomas, J. A., Hörnquist, E. H., Hultgren, O. H.

“…Signalling downstream Toll‐like receptors (TLR) is regulated at several levels in order to activate the immune response and prevent excessive inflammation…”
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The mucosal adjuvant effects of cholera toxin and immune‐stimulating complexes differ in their requirement for IL‐12, indicating different pathways of action by Grdic, Dubravka, Smith, Rosemary, Donachie, Anne, Kjerrulf, Martin, Hörnquist, Elisabeth, Mowat, Allan, Lycke, Nils

“…Adjuvants that can improve mucosal vaccine efficacy are much warranted. In this comparative study between cholera toxin (CT) and immune‐stimulating complexes…”
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Immune Activation in the Intestinal Mucosa Before the Onset of Colitis in Gαi2‐Deficient Mice by Oehman, L, Franzen, L, Rudolph, U, Harriman, G R, Hultgren Hoernquist, E

“…G‐protein subunit Gαi2‐deficient mice spontaneously develop an inflammatory bowel disease that clinically and histopathologically resembles ulcerative colitis…”
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Acellular Bordetella pertussis vaccine enhances mucosal interleukin‐10 production, induces apoptosis of activated Th1 cells and attenuates colitis in Gαi2‐deficient mice by Öhman, L., Willén, R., Hultgren, O. H., Hultgren Hörnquist, E.

“…Summary Mice deficient for the inhibitory G protein subunit α2 (Gαi2–/–) spontaneously develop a progressive inflammatory bowel disease resembling ulcerative…”
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Lack of local suppression in orally tolerant CD8-deficient mice reveals a critical regulatory role of CD8 super(+) T cells in the normal gut mucosa by Grdic, D, Hoernquist, E, Kjerrulf, M, Lycke, N Y

“…We found that feeding keyhole limpet hemocyanin (KLH) to CD8-deficient (CD8 super(-/-)) mice induced oral tolerance that was comparable in both magnitude and…”
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CD8‐deficient mice exhibit augmented mucosal immune responses and intact adjuvant effects to cholera toxin by HÖRNQUIST, E., GRDÌC, D., MAK, T., LYCKE, N.

“…We used normal, CD4 and CD8 gene‐targeted mice to investigate the role of CD4+ and CD8+ T cells in the regulation of gut mucosal immune responses following…”
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The Influence of Costimulation and Regulatory CD4 super(+) T Cells on Intestinal IgA Immune Responses by Gaerdby, E, Kagrdic, D, Kjerrulf, M, Bromander, A, Vajdy, M, Hoernquist, E, Lycke, N

“…It is thought that IgA B-cell differentiation is highly dependent on activated CD4 super(+) T cells. In particular, cell-cell interactions in the Peyer's…”
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Paradoxical IgA immunity in CD4-deficient mice. Lack of cholera toxin- specific protective immunity despite normal gut mucosal IgA differentiation by Hornquist, CE, Ekman, L, Grdic, KD, Schon, K, Lycke, NY

“…Using normal and CD4 gene-targeted (CD4-/-) mice, we asked whether mucosal immune responses and IgA B cell differentiation require the presence of CD4+ T…”
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G alpha i2-deficient mice with colitis exhibit a local increase in memory CD4 super(+) T cells and proinflammatory Th1-type cytokines by Hoernquist, CE, Lu, Xiaohui, Rogers-Fani, P M, Rudolph, U, Shappell, S, Birnbaumer, L, Harriman, G R

“…Mice with targeted deletion of the G protein G alpha i2 develop an inflammatory bowel disease closely resembling ulcerative colitis. To better define disease…”
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