Search Results - "Hoepker, Alexander C"

Quantifying Hormone Disruptors with an Engineered Bacterial Biosensor by Furst, Ariel L, Hoepker, Alexander C, Francis, Matthew B

“…Endocrine disrupting compounds are found in increasing amounts in our environment, originating from pesticides, plasticizers, and pharmaceuticals, among other…”
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1,4-Addition of Lithium Diisopropylamide to Unsaturated Esters: Role of Rate-Limiting Deaggregation, Autocatalysis, Lithium Chloride Catalysis, and Other Mixed Aggregation Effects by Ma, Yun, Hoepker, Alexander C, Gupta, Lekha, Faggin, Marc F, Collum, David B

“…Lithium diisopropylamide (LDA) in tetrahydrofuran at −78 °C undergoes 1,4-addition to an unsaturated ester via a rate-limiting deaggregation of LDA dimer…”
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Regioselective Lithium Diisopropylamide-Mediated Ortholithiation of 1-Chloro-3-(trifluoromethyl)benzene: Role of Autocatalysis, Lithium Chloride Catalysis, and Reversibility by Hoepker, Alexander C, Gupta, Lekha, Ma, Yun, Faggin, Marc F, Collum, David B

“…Ortholithiation of 1-chloro-3-(trifluoromethyl)benzene with lithium diisopropylamide (LDA) in tetrahydrofuran at −78 °C displays characteristics of reactions…”
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Genetically encoded sensors of protein hydrodynamics and molecular proximity by Hoepker, Alexander C., Wang, Ariel, Le Marois, Alix, Suhling, Klaus, Yan, Yuling, Marriott, Gerard

“…Significance The lumazine binding protein (LUMP) emits a cyan-colored fluorescence and has the longest average fluorescence lifetime of any genetically encoded…”
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Autocatalysis in Lithium Diisopropylamide-Mediated Ortholithiations by Singh, Kanwal J, Hoepker, Alexander C, Collum, David B

“…Ortholithiation of 3-fluorophenyl-N,N-diisopropyl carbamate by lithium diisopropylamide (LDA) in THF at −78 °C affords unusual rate behavior including linear…”
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Lithium Diisopropylamide-Mediated Ortholithiations: Lithium Chloride Catalysis by Gupta, Lekha, Hoepker, Alexander C, Singh, Kanwal J, Collum, David B

“…Ortholithiations of a range of arenes mediated by lithium diisopropylamide (LDA) in THF at −78 °C reveal substantial accelerations by as little as 0.5 mol % of…”
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Lithium Diisopropylamide: Nonequilibrium Kinetics and Lessons Learned about Rate Limitation by Algera, Russell F, Gupta, Lekha, Hoepker, Alexander C, Liang, Jun, Ma, Yun, Singh, Kanwal J, Collum, David B

“…The kinetics of lithium diisopropylamide (LDA) in tetrahydrofuran under nonequilibrium conditions are reviewed. These conditions correspond to a class of…”
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Computational Studies of Lithium Diisopropylamide Deaggregation by Hoepker, Alexander C, Collum, David B

“…Density functional theory computations [MP2/6-31G(d)//B3LYP/6-31G(d)] on the deaggregation of lithium diisopropylamide (LDA) dimer solvated by two…”
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Addition of Cl2C:  to (−)-O-Menthyl Acrylate under Sonication−Phase-Transfer Catalysis. Efficient Synthesis of (+)- and (−)-(2-Chlorocyclopropyl)methanol by Masuno, Makoto N, Young, Douglas M, Hoepker, Alexander C, Skepper, Colin K, Molinski, Tadeusz F

“…Dichlorocyclopropanation of (−)-O-menthyl acrylate under conditions of phase-transfer catalysis (CHCl3, KOH, tetramethylammonium bromide), with sonication,…”
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Mechanism of Lithium Diisopropylamide-Mediated Ortholithiation of 1,4-Bis(trifluoromethyl)benzene under Nonequilibrium Conditions: Condition-Dependent Rate Limitation and Lithium Chloride-Catalyzed Inhibition by Liang, Jun, Hoepker, Alexander C, Algera, Russell F, Ma, Yun, Collum, David B

“…Lithiation of 1,4-bis­(trifluoromethyl)­benzene with lithium diisopropylamide in tetrahydrofuran at −78 °C occurs under conditions at which the rates of…”
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Lithium Diisopropylamide-Mediated Lithiation of 1,4-Difluorobenzene under Nonequilibrium Conditions: Role of Monomer‑, Dimer‑, and Tetramer-Based Intermediates and Lessons about Rate Limitation by Liang, Jun, Hoepker, Alexander C, Bruneau, Angela M, Ma, Yun, Gupta, Lekha, Collum, David B

“…Lithiation of 1,4-difluorobenzene with lithium diisopropylamide (LDA) in THF at −78 °C joins the ranks of a growing number of metalations that occur under…”
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Lithium Diisopropylamide-Mediated Ortholithiation of 2‑Fluoropyridines: Rates, Mechanisms, and the Role of Autocatalysis by Gupta, Lekha, Hoepker, Alexander C, Ma, Yun, Viciu, Mihai S, Faggin, Marc F, Collum, David B

“…Lithium diisopropylamide (LDA)-mediated ortholithiations of 2-fluoropyridine and 2,6-difluoropyridine in tetrahydrofuran at −78 °C were studied using a…”
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Structural and Biochemical Studies of Actin in Complex with Synthetic Macrolide Tail Analogues by Pereira, Jose H., Petchprayoon, Chutima, Hoepker, Alexander C., Moriarty, Nigel W., Fink, Sarah J., Cecere, Giuseppe, Paterson, Ian, Adams, Paul D., Marriott, Gerard

“…The actin filament‐binding and filament‐severing activities of the aplyronine, kabiramide, and reidispongiolide families of marine macrolides are located…”
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1-O-Sulfatobastadins-1 and -2 from Ianthella basta (Pallas).Antagonists of the yR1-FKBP12 Ca2+ Channel by Masuno, Makoto N., Hoepker, Alexander C., Pessah, Isaac N., Molinski, Tadeusz F.

“…Two new sulfate monoesters of hemibastadins-1 and -2 were isolated from the marine sponge Ianthella basta (Pallas) from Guam. A third new compound was…”
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Lithium Diisopropylamide: Non-Equilibrium Kinetics and Lessons Learned about Rate Limitation by Algera, Russell F., Gupta, Lekha, Hoepker, Alexander C., Liang, Jun, Ma, Yun, Singh, Kanwal J., Collum, David B.

“…The kinetics of lithium diisopropylamide (LDA) in tetrahydrofuran under non-equilibrium conditions are reviewed. These conditions correspond to a class of…”
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Autocatalysis in Lithium Diisopropylamide-MediatedOrtholithiations by Singh, Kanwal J., Hoepker, Alexander C., Collum, David B.

“…Ortholithiation of 3-fluorophenyl- N,N -diisopropyl carbamate by lithium diisopropylamide (LDA) in THF at −78 °C affords unusual rate behavior including linear…”
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Addition of Cl 2 C:  to (−)- O -Menthyl Acrylate under Sonication−Phase-Transfer Catalysis. Efficient Synthesis of (+)- and (−)-(2-Chlorocyclopropyl)methanol by Masuno, Makoto N., Young, Douglas M., Hoepker, Alexander C., Skepper, Colin K., Molinski, Tadeusz F.

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1-O-Sulfatobastadins-1 and -2 from Ianthella basta (Pallas). Antagonists of the RyR1-FKBP12 Ca super(2+) Channel by Masuno, Makoto N, Hoepker, Alexander C, Pessah, Isaac N, Molinski, Tadeusz F

“…Two new sulfate monoesters of hemibastadins-1 and -2 were isolated from the marine sponge Ianthella basta (Pallas) from Guam. A third new compound was…”
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1-O-Sulfatobastadins-1 and -2 from Ianthella basta (Pallas). Antagonists of the RyR1-FKBP12 Ca2+ Channel by Masuno, Makoto N., Hoepker, Alexander C., Pessah, Isaac N., Molinski, Tadeusz F.

“…Two new sulfate monoesters of hemibastadins-1 and -2 were isolated from the marine sponge Ianthella basta (Pallas) from Guam. A third new compound was…”
Get full text