Search Results - "Hoelzinger, Dominique B"

The phosphorylation of ephrin‐B2 ligand promotes glioma cell migration and invasion by Nakada, Mitsutoshi, Anderson, Eric M., Demuth, Tim, Nakada, Satoko, Reavie, Linsey B., Drake, Kelsey L., Hoelzinger, Dominique B., Berens, Michael E.

“…To reveal molecular drivers of glioma invasion, two distinct glioblastoma (GBM) cell phenotypes (invading cells and tumor core cells) were collected from 19…”
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Foxp3-positive macrophages display immunosuppressive properties and promote tumor growth by Manrique, Soraya Zorro, Correa, Maria Adelaida Duque, Hoelzinger, Dominique B, Dominguez, Ana Lucia, Mirza, Noweeda, Lin, Hsi-Hsien, Stein-Streilein, Joan, Gordon, Siamon, Lustgarten, Joseph

“…Regulatory T cells (T reg cells) are characterized by the expression of the forkhead lineage-specific transcription factor Foxp3, and their main function is to…”
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MUC1 Vaccines, Comprised of Glycosylated or Non-Glycosylated Peptides or Tumor-Derived MUC1, Can Circumvent Immunoediting to Control Tumor Growth in MUC1 Transgenic Mice by Lakshminarayanan, Vani, Supekar, Nitin T, Wei, Jie, McCurry, Dustin B, Dueck, Amylou C, Kosiorek, Heidi E, Trivedi, Priyanka P, Bradley, Judy M, Madsen, Cathy S, Pathangey, Latha B, Hoelzinger, Dominique B, Wolfert, Margreet A, Boons, Geert-Jan, Cohen, Peter A, Gendler, Sandra J

“…It remains challenging to produce decisive vaccines against MUC1, a tumor-associated antigen widely expressed by pancreas, breast and other tumors. Employing…”
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Gene Expression Profile of Glioblastoma Multiforme Invasive Phenotype Points to New Therapeutic Targets by Hoelzinger, Dominique B., Mariani, Luigi, Weis, Joachim, Woyke, Tanja, Berens, Theresa J., McDonough, WendyS, Sloan, Andrew, Coons, Stephen W., Berens, Michael E.

“…The invasive phenotype of glioblastoma multiforme (GBM) is a hallmark of malignant process, yet molecular mechanisms that dictate this locally invasive…”
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Stage-Specific Non-Coding RNA Expression Patterns during In Vitro Human B Cell Differentiation into Antibody Secreting Plasma Cells by Tschumper, Renee C, Hoelzinger, Dominique B, Walters, Denise K, Davila, Jaime I, Osborne, Collin A, Jelinek, Diane F

“…The differentiation of B cells into antibody secreting plasma cells (PCs) is governed by a strict regulatory network that results in expression of specific…”
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MAP-ing glioma invasion: Mitogen-activated protein kinase kinase 3 and p38 drive glioma invasion and progression and predict patient survival by Demuth, Tim, Reavie, Linsey B, Rennert, Jessica L, Nakada, Mitsutoshi, Nakada, Satoko, Hoelzinger, Dominique B, Beaudry, Christian E, Henrichs, Amanda N, Anderson, Eric M, Berens, Michael E

“…Although astrocytic brain tumors do not metastasize systemically, during tumorigenesis glioma cells adopt an invasive phenotype that is poorly targeted by…”
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Glioma cells on the run - the migratory transcriptome of 10 human glioma cell lines by Demuth, Tim, Rennert, Jessica L, Hoelzinger, Dominique B, Reavie, Linsey B, Nakada, Mitsutoshi, Beaudry, Christian, Nakada, Satoko, Anderson, Eric M, Henrichs, Amanda N, McDonough, Wendy S, Holz, David, Joy, Anna, Lin, Richard, Pan, Kuang H, Lih, Chih J, Cohen, Stan N, Berens, Michael E

“…Glioblastoma multiforme (GBM) is the most common primary intracranial tumor and despite recent advances in treatment regimens, prognosis for affected patients…”
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The Human Fn14 Receptor Gene Is Up-Regulated in Migrating Glioma Cells in Vitro and Overexpressed in Advanced Glial Tumors by Tran, Nhan L., McDonough, Wendy S., Donohue, Patrick J., Winkles, Jeffrey A., Berens, Theresa J., Ross, Kristen R., Hoelzinger, Dominique B., Beaudry, Christian, Coons, Stephen W., Berens, Michael E.

“…Glioblastoma multiforme comprises the majority of human brain tumors. Patients with glioblastoma multiforme have poor survival rates, with an average life…”
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Autocrine Factors That Sustain Glioma Invasion and Paracrine Biology in the Brain Microenvironment by Hoelzinger, Dominique B., Demuth, Tim, Berens, Michael E.

“…Invasion is a defining hallmark of glioblastoma multiforme, just as metastasis characterizes other high-grade tumors. Glial tumors invariably recur due to the…”
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Inhibition of adaptive immunity by IL9 can be disrupted to achieve rapid T-cell sensitization and rejection of progressive tumor challenges by Hoelzinger, Dominique B, Dominguez, Ana Lucia, Cohen, Peter A, Gendler, Sandra J

“…The tolerogenic cytokine IL9 promotes T regulatory cell function and allergic airway inflammation, but it has not been extensively studied in cancer. In this…”
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Blockade of CCL1 inhibits T regulatory cell suppressive function enhancing tumor immunity without affecting T effector responses by Hoelzinger, Dominique B, Smith, Shannon E, Mirza, Noweeda, Dominguez, Ana Lucia, Manrique, Soraya Zorro, Lustgarten, Joseph

“…Intratumoral accumulation of T regulatory cells (Tregs) creates an immunosuppressive environment that reduces the efficacy of antitumor immunotherapy. The…”
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Death-associated Protein 3 (Dap-3) Is Overexpressed in Invasive Glioblastoma Cells in Vivo and in Glioma Cell Lines with Induced Motility Phenotype in Vitro by MARIANI, Luigi, BEAUDRY, Christian, MCDONOUGH, Wendy S, HOELZINGER, Dominique B, KACZMAREK, Elzbieta, PONCE, Francisco, COONS, Stephen W, GIESE, Alf, SEILER, Rolf W, BERENS, Michael E

“…Purpose: To discover the genetic determinants of glioma invasion in vivo , we compared the mRNA expression profiles of glioblastoma cells residing at the tumor…”
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Comparative kinetic analyses of gene profiles of naïve CD4+ and CD8+ T cells from young and old animals reveal novel age‐related alterations by Mirza, Noweeda, Pollock, Kevin, Hoelzinger, Dominique B., Dominguez, Ana Lucia, Lustgarten, Joseph

“…Summary It is well established that immune responses are diminished in the old. However, we still do not have a clear understanding of what dictates the…”
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Signals through 4-1BB inhibit T regulatory cells by blocking IL-9 production enhancing antitumor responses by Smith, Shannon E., Hoelzinger, Dominique B., Dominguez, Ana Lucia, Van Snick, Jacques, Lustgarten, Joseph

“…Previous studies from our laboratory indicate that intratumoral (i.t.) injections of CpG-ODN are the most effective adjuvant strategy to induce an antitumor…”
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Increased fibroblast growth factor-inducible 14 expression levels promote glioma cell invasion via Rac1 and nuclear factor-κB and correlate with poor patient outcome by TRAIL, Nhan L, MCDONOUGH, Wendy S, RENNERT, Jessica L, MICHAELSON, Jennifer S, BURKLY, Linda C, LIPINSKI, Christopher A, LOFTUS, Joseph C, MARIANI, Luigi, BERENS, Michael E, SAVITCH, Benjamin A, FORTIN, Shannon P, WINKLES, Jeffrey A, SYMONS, Marc, NAKADA, Mitsutoshi, CUNLIFFE, Heather E, HOSTELLER, Galen, HOELZINGER, Dominique B

“…Abstract Glial tumors progress to malignant grades by heightened proliferation and relentless dispersion throughout the central nervous system. Understanding…”
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Extracellular vesicle proteomic analysis leads to the discovery of HDGF as a new factor in multiple myeloma biology by Hoelzinger, Dominique B., Quinton, Sophia J., Walters, Denise K., Vardam-Kaur, Trupti, Tschumper, Renee C., Borges da Silva, Henrique, Jelinek, Diane F.

“…Identifying factors secreted by multiple myeloma (MM) cells that may contribute to MM tumor biology and progression is of the utmost importance. In this study,…”
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Chemotherapy can induce weight normalization of morbidly obese mice despite undiminished ingestion of high fat diet by Myers, Cheryl E, Hoelzinger, Dominique B, Truong, Tiffany N, Chew, Lindsey A, Myles, Arpita, Chaudhuri, Leena, Egan, Jan B, Liu, Jun, Gendler, Sandra J, Cohen, Peter A

“…Morbidly obese patients who accomplish substantial weight loss often display a long-term decline in their resting metabolism, causing even relatively…”
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Autotaxin: a secreted autocrine/paracrine factor that promotes glioma invasion by Hoelzinger, Dominique B., Nakada, Mitsutoshi, Demuth, Tim, Rosensteel, Tyler, Reavie, Linsey B., Berens, Michael E.

“…Glioblastoma multiforme (GBM) is inherently invasive, and it is from the invasive cell population that the tumor recurs. The GBM invasion transcriptome reveals…”
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Differential Gene Expression in Auristatin PHE-Treated Cryptococcus neoformans by Woyke, Tanja, Berens, Michael E, Hoelzinger, Dominique B, Pettit, George R, Winkelmann, Günther, Pettit, Robin K

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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CpG-ODN but not other TLR-ligands restore the antitumor responses in old mice: the implications for vaccinations in the aged by Sharma, Sanjay, Dominguez, Ana Lucia, Hoelzinger, Dominique B., Lustgarten, Joseph

“…Aim There is accumulative evidence indicating that targeting antigen presenting cells (APCs) with different types of adjuvants could result in the induction of…”
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