Search Results - "Hoek, Tim A."

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  1. 1

    Dynamics of Translation of Single mRNA Molecules In Vivo by Yan, Xiaowei, Hoek, Tim A., Vale, Ronald D., Tanenbaum, Marvin E.

    Published in Cell (05-05-2016)
    “…Regulation of mRNA translation, the process by which ribosomes decode mRNAs into polypeptides, is used to tune cellular protein levels. Currently, methods for…”
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    Journal Article
  2. 2

    Resource Availability Modulates the Cooperative and Competitive Nature of a Microbial Cross-Feeding Mutualism by Hoek, Tim A, Axelrod, Kevin, Biancalani, Tommaso, Yurtsev, Eugene A, Liu, Jinghui, Gore, Jeff

    Published in PLoS biology (24-08-2016)
    “…Mutualisms between species play an important role in ecosystem function and stability. However, in some environments, the competitive aspects of an interaction…”
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  3. 3
  4. 4

    Single-Molecule Imaging Uncovers Rules Governing Nonsense-Mediated mRNA Decay by Hoek, Tim A., Khuperkar, Deepak, Lindeboom, Rik G.H., Sonneveld, Stijn, Verhagen, Bram M.P., Boersma, Sanne, Vermeulen, Michiel, Tanenbaum, Marvin E.

    Published in Molecular cell (25-07-2019)
    “…Nonsense-mediated decay (NMD) is a surveillance system that degrades mRNAs containing a premature termination codon (PTC) and plays important roles in protein…”
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    Journal Article
  5. 5

    Imaging Translation Dynamics of Single mRNA Molecules in Live Cells by Ruijtenberg, Suzan, Hoek, Tim A, Yan, Xiaowei, Tanenbaum, Marvin E

    “…mRNA translation is a key step in decoding the genetic information stored in DNA. Regulation of translation efficiency contributes to gene expression control…”
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    Journal Article
  6. 6

    Dissecting the roles of human BUB1 in the spindle assembly checkpoint by Vleugel, Mathijs, Hoek, Tim A, Tromer, Eelco, Sliedrecht, Tale, Groenewold, Vincent, Omerzu, Manja, Kops, Geert J P L

    Published in Journal of cell science (15-08-2015)
    “…Mitotic chromosome segregation is initiated by the anaphase promoting complex/cyclosome (APC/C) and its co-activator CDC20 (forming APC/C(CDC20)). APC/C(CDC20)…”
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  7. 7

    Quantification of mRNA translation in live cells using single-molecule imaging by Khuperkar, Deepak, Hoek, Tim A., Sonneveld, Stijn, Verhagen, Bram M. P., Boersma, Sanne, Tanenbaum, Marvin E.

    Published in Nature protocols (01-04-2020)
    “…mRNA translation is a key step in gene expression. Proper regulation of translation efficiency ensures correct protein expression levels in the cell, which is…”
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