Search Results - "Hoek, Tim A."
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Dynamics of Translation of Single mRNA Molecules In Vivo
Published in Cell (05-05-2016)“…Regulation of mRNA translation, the process by which ribosomes decode mRNAs into polypeptides, is used to tune cellular protein levels. Currently, methods for…”
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Resource Availability Modulates the Cooperative and Competitive Nature of a Microbial Cross-Feeding Mutualism
Published in PLoS biology (24-08-2016)“…Mutualisms between species play an important role in ecosystem function and stability. However, in some environments, the competitive aspects of an interaction…”
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Correction: Resource Availability Modulates the Cooperative and Competitive Nature of a Microbial Cross-Feeding Mutualism
Published in PLoS biology (01-06-2017)“…[This corrects the article DOI: 10.1371/journal.pbio.1002540.]…”
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Single-Molecule Imaging Uncovers Rules Governing Nonsense-Mediated mRNA Decay
Published in Molecular cell (25-07-2019)“…Nonsense-mediated decay (NMD) is a surveillance system that degrades mRNAs containing a premature termination codon (PTC) and plays important roles in protein…”
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Imaging Translation Dynamics of Single mRNA Molecules in Live Cells
Published in Methods in molecular biology (Clifton, N.J.) (2018)“…mRNA translation is a key step in decoding the genetic information stored in DNA. Regulation of translation efficiency contributes to gene expression control…”
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Dissecting the roles of human BUB1 in the spindle assembly checkpoint
Published in Journal of cell science (15-08-2015)“…Mitotic chromosome segregation is initiated by the anaphase promoting complex/cyclosome (APC/C) and its co-activator CDC20 (forming APC/C(CDC20)). APC/C(CDC20)…”
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Quantification of mRNA translation in live cells using single-molecule imaging
Published in Nature protocols (01-04-2020)“…mRNA translation is a key step in gene expression. Proper regulation of translation efficiency ensures correct protein expression levels in the cell, which is…”
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A public–private partnership model for COVID-19 diagnostics
Published in Nature biotechnology (01-10-2021)Get full text
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