Search Results - "Hoefs, J C"

Quantitative tests of liver function measure hepatic improvement after sustained virological response: results from the HALT‐C trial by EVERSON, G. T., SHIFFMAN, M. L., HOEFS, J. C., MORGAN, T. R., STERLING, R. K., WAGNER, D. A., DESANTO, J. L., CURTO, T. M., WRIGHT, E. C.

“…Summary Backgroud  The impact of virologic response on hepatic function has not been previously defined. Aim  To determine the relationships of quantitative…”
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The spectrum of hepatic functional impairment in compensated chronic hepatitis C : results from the Hepatitis C Anti-viral Long-term Treatment against Cirrhosis Trial by EVERSON, G. T, SHIFFMAN, M. L, MORGAN, T. R, HOEFS, J. C, STERLING, R. K, WAGNER, D. A, KULIG, C. C, CURTO, T. M, WRIGHT, E. C

“…The spectrum of functional impairment in patients with compensated chronic hepatitis C is incompletely defined. To define hepatic impairment by quantitative…”
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Portal‐systemic shunting in patients with fibrosis or cirrhosis due to chronic hepatitis C: the minimal model for measuring cholate clearances and shunt by EVERSON, G. T., MARTUCCI, M. A., SHIFFMAN, M. L., STERLING, R. K., MORGAN, T. R., HOEFS, J. C.

“…Summary Background  Measurement of portal inflow and portal‐systemic shunt using cholate clearances could be useful in monitoring patients with liver disease…”
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Ascitic fluid analysis in malignancy-related ascites by Runyon, B A, Hoefs, J C, Morgan, T R

“…A prospective study identified 45 patients with malignancy-related ascites among 448 ascites patients (10% of the total). Patients were categorized into five…”
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A randomized, double-blind trial comparing pegylated interferon alfa-2b to interferon alfa-2b as initial treatment for chronic hepatitis C by Lindsay, Karen L., Trepo, Christian, Heintges, Tobias, Shiffman, Mitchell L., Gordon, Stuart C., Hoefs, John C., Schiff, Eugene R., Goodman, Zachary D., Laughlin, Mark, Yao, Ruji, Albrecht, Janice K.

“…This international, randomized, active-controlled, parallel-group, double-blind dose-finding study compared peginterferon alfa-2b (PegIntron™) to interferon…”
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Functional measurement of nonfibrotic hepatic mass in cirrhotic patients by Hoefs, J C, Wang, F, Kanel, G

“…We have postulated that the perfused hepatic mass (PHM) can be estimated by quantitative (volumetric) liver spleen scan (QLSS) using single photon emission…”
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Diagnostic paracentesis. A potent clinical tool by Hoefs, J C

“…Diagnostic paracentesis is a potent diagnostic tool capable of rapidly detecting portal hypertension and peritonitis. Gram's stain and chemical analysis of…”
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Culture-negative neutrocytic ascites: a variant of spontaneous bacterial peritonitis by Runyon, B A, Hoefs, J C

“…A review of the medical records of patients diagnosed as having "spontaneous bacterial peritonitis" (SBP) revealed 18 episodes of culture-negative neutrocytic…”
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Spontaneous bacterial peritonitis: prevention and therapy by Hoefs, J C

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Treatment of chronic hepatitis C with consensus interferon: A multicenter, randomized, controlled trial by Tong, M J, Reddy, K R, Lee, W M, Pockros, P J, Hoefs, J C, Keeffe, E B, Hollinger, F B, Hathcote, E J, White, H, Foust, R T, Jensen, D M, Krawitt, E L, Fromm, H, Black, M, Blatt, L M, Klein, M, Lubina, J

“…This multicenter, randomized, controlled, double‐blind, phase III study in 704 patients with chronic hepatitis C infection compared treatment with consensus…”
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Globulin correction of the albumin gradient: correlation with measured serum to ascites colloid osmotic pressure gradients by Hoefs, J C

“…The albumin difference or gradient between serum ascites is presumed to be an effective estimate of the colloid osmotic pressure gradient, although this has…”
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Opsonic activity of human ascitic fluid: a potentially important protective mechanism against spontaneous bacterial peritonitis by Runyon, B A, Morrissey, R L, Hoefs, J C, Wyle, F A

“…The opsonic activity of 60 ascitic fluids from 47 patients was measured using a standard opsonophagocytic assay. Curve analysis of the opsonic activity…”
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Measurement of portal shunting in dogs by Hoefs, J C

“…A new method for measuring the quantity of portal blood bypassing the liver (shunted) has been developed and tested in the dog. Shunts were mimicked by the…”
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Ascitic fluid analysis in the differentiation of spontaneous bacterial peritonitis from gastrointestinal tract perforation into ascitic fluid by Runyon, B A, Hoefs, J C

“…A review of patients with bacterial peritonitis and ascites revealed six patients with gastrointestinal tract perforation into their ascitic fluid and 33…”
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Raising the dose of interferon does not improve the response in chronic hepatitis C by Fong, T L, Morgan, T R, Phan, C G, Hoefs, J C

“…We report results of dose escalation to 5 or 6 million units (MU) three times weekly (t.i.w.) of interferon-alpha in 17 consecutive patients with chronic…”
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Hepatofugal portal flow in cirrhosis: observations on hepatic hemodynamics and the nature of the arterioportal communications by Rector, Jr, W G, Hoefs, J C, Hossack, K F, Everson, G T

“…Six of 85 patients (7%) with alcoholic liver disease undergoing transhepatic portal pressure measurement had either stagnant (3 patients) or reversed (3…”
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A Novel, Simple Method of Functional Spleen Volume Calculation by Liver-Spleen Scan by Hoefs, John C, Wang, Felix W, Lilien, David L, Walker, Barbara, Kanel, Gary

“…Spleen enlargement is commonly associated with portal hypertension from cirrhosis and may cause thrombocytopenia. Thus, accurate assessment of spleen size may…”
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Ascitic fluid chemical analysis before, during and after spontaneous bacterial peritonitis by Runyon, B A, Hoefs, J C

“…A retrospective analysis of 22 patients whose ascitic fluid had been analyzed prior to the onset of spontaneous bacterial peritonitis, during infection and/or…”
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Diagnostic paracentesis by Hoefs, J C, Jonas, G M

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264 MINIMAL MODEL TO DETERMINE FIRST-PASS HEPATIC EXTRACTION OF CHOLATE IN HUMANS by Martucci, M. A., Everson, G. T., Shiffman, M. L., Hoefs, J. C.

“…PurposeTo mathematically model clearance curves of cholate administered intravenously (13C) and orally (2H) to patients with chronic hepatitis C (HALT-C…”
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