Search Results - "Hoefnagel, Sanne J. M."

Gene expression profiles of esophageal squamous cell cancers in Hodgkin lymphoma survivors versus sporadic cases by Ykema, Berbel L M, Hoefnagel, Sanne J M, Rigter, Lisanne S, Kodach, Liudmila L, Meijer, Gerrit A, van Leeuwen, Flora E, Khan, Hina N, Snaebjornsson, Petur, Aleman, Berthe M P, Broeks, Annegien, Meijer, Sybren L, Wang, Kenneth K, Carvalho, Beatriz, Krishnadath, Kausilia K, van Leerdam, Monique E

“…Hodgkin lymphoma (HL) survivors are at increased risk of developing second primary esophageal squamous cell cancer (ESCC). We aimed to gain insight in the…”
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Selective targeting BMP2 and 4 in SMAD4 negative esophageal adenocarcinoma inhibits tumor growth and aggressiveness in preclinical models by Li, Shulin, Hoefnagel, Sanne J. M., Read, Matthew, Meijer, Sybren, van Berge Henegouwen, Mark I., Gisbertz, Suzanne S., Bonora, Elena, Liu, David S. H., Phillips, Wayne A., Calpe, Silvia, Correia, Ana C. P., Sancho-Serra, Maria D. C., Mattioli, Sandro, Krishnadath, Kausilia K.

“…Purpose Abnormalities within the Sonic Hedgehog (SHH), Bone Morphogenetic Protein (BMP) and SMAD4 signalling pathways have been associated with the malignant…”
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Identification of Novel Molecular Subgroups in Esophageal Adenocarcinoma to Predict Response to Neo-Adjuvant Therapies by Hoefnagel, Sanne J. M, Koemans, Willem J, Khan, Hina N, Koster, Jan, Meijer, Sybren L, van Dieren, Jolanda M, Kodach, Liudmila L, van Sandick, Johanna W, Calpe, Silvia, del Sancho-Serra, Carmen M, Correia, Ana C. P, Van Berge Henegouwen, Mark I, Gisbertz, Suzanne S, Hulshof, Maarten C. C. M, Mattioli, Sandro, Spaander, Manon C. W, Krishnadath, Kausilia K

“…Esophageal adenocarcinoma (EAC) is a highly aggressive cancer and its response to chemo- and radiotherapy is unpredictable. EACs are highly heterogeneous at…”
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microRNA 125a Regulates MHC-I Expression on Esophageal Adenocarcinoma Cells, Associated With Suppression of Antitumor Immune Response and Poor Outcomes of Patients by Mari, Luigi, Hoefnagel, Sanne J.M., Zito, Domenico, van de Meent, Marian, van Endert, Peter, Calpe, Silvia, Sancho Serra, Maria del Carmen, Heemskerk, Mirjam H.M., van Laarhoven, Hanneke W.M., Hulshof, Maarten C.C.M., Gisbertz, Susanne S., Medema, Jan Paul, van Berge Henegouwen, Mark I., Meijer, Sybren L., Bergman, Jacques J.G.H.M., Milano, Francesca, Krishnadath, Kausilia K.

“…Immune checkpoint inhibition may affect growth or progression of highly aggressive cancers, such as esophageal adenocarcinoma (EAC). We investigated the…”
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Towards Personalized Treatment Strategies for Esophageal Adenocarcinoma; A Review on the Molecular Characterization of Esophageal Adenocarcinoma and Current Research Efforts on Individualized Curative Treatment Regimens by Hoefnagel, Sanne J. M., Boonstra, Jurjen J., Russchen, Marjolein J. A. M., Krishnadath, Kausilia K.

“…Esophageal cancers confer a major health challenge and are highly aggressive malignancies with poor prognosis. Esophageal adenocarcinoma (EAC) is one of the…”
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Inhibition of BMP2 and BMP4 Represses Barrett’s Esophagus While Enhancing the Regeneration of Squamous Epithelium in Preclinical Models by Correia, Ana C.P., Straub, Danielle, Read, Matthew, Hoefnagel, Sanne J.M., Romero-Pinedo, Salvador, Abadía-Molina, Ana C., Clemons, Nicholas J., Wang, Kenneth, Calpe, Silvia, Phillips, Wayne, Krishnadath, Kausilia K.

“…Barrett’s esophagus is considered to be a metaplastic lesion that predisposes for esophageal adenocarcinoma. Development of Barrett’s esophagus is considered…”
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Novel metastatic models of esophageal adenocarcinoma derived from FLO-1 cells highlight the importance of E-cadherin in cancer metastasis by Liu, David S, Hoefnagel, Sanne J M, Fisher, Oliver M, Krishnadath, Kausilia K, Montgomery, Karen G, Busuttil, Rita A, Colebatch, Andrew J, Read, Matthew, Duong, Cuong P, Phillips, Wayne A, Clemons, Nicholas J

“…There is currently a paucity of preclinical models available to study the metastatic process in esophageal cancer. Here we report FLO-1, and its isogenic…”
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Spray cryotherapy versus continued radiofrequency ablation in persistent Barrett’s esophagus by Genere, Juan Reyes, Visrodia, Kavel, Zakko, Liam, Hoefnagel, Sanne J M, Wang, Kenneth K

“…Abstract Radiofrequency ablation (RFA) is the first-line treatment for flat Barrett’s esophagus (BE) with dysplasia, however its role for persistent Barrett’s…”
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Increased PXR and Suppressed T-Cell Signaling Are Associated With Malignant Degeneration of Barrett’s Esophagus by Hoefnagel, Sanne J.M., Li, Shulin, Timmer, Eva M., Meijer, Sybren L., Krishnadath, Kausilia K.

“…Barrett's esophagus (BE) is the precursor lesion for esophageal adenocarcinoma (EAC). To detect EAC in early stage, patients with BE undergo endoscopic…”
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