Search Results - "Hoefnagel, Laurien D"

Receptor conversion in distant breast cancer metastases by Hoefnagel, Laurien D C, van de Vijver, Marc J, van Slooten, Henk-Jan, Wesseling, Pieter, Wesseling, Jelle, Westenend, Pieter J, Bart, Joost, Seldenrijk, Cornelis A, Nagtegaal, Iris D, Oudejans, Joost, van der Valk, Paul, van der Groep, Petra, de Vries, Elisabeth G E, van der Wall, Elsken, van Diest, Paul J

“…When breast cancer patients develop distant metastases, the choice of systemic treatment is usually based on tissue characteristics of the primary tumor as…”
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PI3K/AKT/mTOR pathway activation in primary and corresponding metastatic breast tumors after adjuvant endocrine therapy by Beelen, Karin, Hoefnagel, Laurien D.C., Opdam, Mark, Wesseling, Jelle, Sanders, J., Vincent, Andrew D., Diest, Paul J., Linn, Sabine C.

“…Both preclinical and clinical data suggest that activation of the PI3K/AKT/mTOR pathway in response to hormonal therapy results in acquired endocrine therapy…”
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Prognostic value of estrogen receptor α and progesterone receptor conversion in distant breast cancer metastases by Hoefnagel, Laurien D. C., Moelans, Cathy B., Meijer, S. L., van Slooten, Henk‐Jan, Wesseling, Pieter, Wesseling, Jelle, Westenend, Pieter J., Bart, Joost, Seldenrijk, Cornelis A., Nagtegaal, Iris D., Oudejans, Joost, van der Valk, Paul, van Gils, Carla H., van der Wall, Elsken, van Diest, Paul J.

“…BACKGROUND: Changes in the receptor profile of primary breast cancers to their metastases (receptor conversion) have been described for the estrogen receptor α…”
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Genomic evolution from primary breast carcinoma to distant metastasis: Few copy number changes of breast cancer related genes by Moelans, Cathy B, van der Groep, Petra, Hoefnagel, Laurien D.C, van de Vijver, Marc J, Wesseling, Pieter, Wesseling, Jelle, van der Wall, Elsken, van Diest, Paul J

“…Abstract Cancer initiation and progression is characterized by (epi)genetic aberrations. However, little is known about the changes that occur during breast…”
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Upregulation of Claudin-4, CAIX and GLUT-1 in distant breast cancer metastases by Jiwa, Laura S, van Diest, Paul J, Hoefnagel, Laurien D, Wesseling, Jelle, Wesseling, Pieter, Moelans, Cathy B

“…Several studies have shown that the immunophenotype of distant breast cancer metastases may differ significantly from that of the primary tumor, especially…”
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The prognostic effect of DDX3 upregulation in distant breast cancer metastases by Heerma van Voss, Marise R., Schrijver, Willemijne A. M. E., ter Hoeve, Natalie D., Hoefnagel, Laurien D., Manson, Quirine F., van der Wall, Elsken, Raman, Venu, van Diest, Paul J.

“…Metastatic breast cancer remains one of the leading causes of death in women and identification of novel treatment targets is therefore warranted. Functional…”
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Influence of decalcification procedures on immunohistochemistry and molecular pathology in breast cancer by Schrijver, Willemijne A M E, van der Groep, Petra, Hoefnagel, Laurien DC, ter Hoeve, Natalie D, Peeters, Ton, Moelans, Cathy B, van Diest, Paul J

“…Distant breast cancer metastases are nowadays routinely biopsied to reassess receptor status and to isolate DNA for sequencing of druggable targets. Bone…”
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Testing for discordance at metastatic relapse of breast cancer matters by van Diest, Paul J, Hoefnagel, Laurien D C, van der Wall, Elsken

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