Search Results - "Hoefnagel, D"

Risk factors for infections related to external ventricular drainage by Hoefnagel, D., Dammers, R., Ter Laak-Poort, M. P., Avezaat, C. J. J.

“…Summary Background. External ventricular drainage (EVD) is frequently used in neurosurgery for cerebrospinal fluid (CSF) drainage in patients with raised…”
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Receptor conversion in distant breast cancer metastases by Hoefnagel, Laurien D C, van de Vijver, Marc J, van Slooten, Henk-Jan, Wesseling, Pieter, Wesseling, Jelle, Westenend, Pieter J, Bart, Joost, Seldenrijk, Cornelis A, Nagtegaal, Iris D, Oudejans, Joost, van der Valk, Paul, van der Groep, Petra, de Vries, Elisabeth G E, van der Wall, Elsken, van Diest, Paul J

“…When breast cancer patients develop distant metastases, the choice of systemic treatment is usually based on tissue characteristics of the primary tumor as…”
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PI3K/AKT/mTOR pathway activation in primary and corresponding metastatic breast tumors after adjuvant endocrine therapy by Beelen, Karin, Hoefnagel, Laurien D.C., Opdam, Mark, Wesseling, Jelle, Sanders, J., Vincent, Andrew D., Diest, Paul J., Linn, Sabine C.

“…Both preclinical and clinical data suggest that activation of the PI3K/AKT/mTOR pathway in response to hormonal therapy results in acquired endocrine therapy…”
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Letter to the editor: Progressive neurology in a young woman with a known Currarino’s triad by Hoefnagel, D., Spoor, J. K. H., Dammers, R., Dirven, C. M. F., de Jong, T. H. R.

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Prognostic value of estrogen receptor α and progesterone receptor conversion in distant breast cancer metastases by Hoefnagel, Laurien D. C., Moelans, Cathy B., Meijer, S. L., van Slooten, Henk‐Jan, Wesseling, Pieter, Wesseling, Jelle, Westenend, Pieter J., Bart, Joost, Seldenrijk, Cornelis A., Nagtegaal, Iris D., Oudejans, Joost, van der Valk, Paul, van Gils, Carla H., van der Wall, Elsken, van Diest, Paul J.

“…BACKGROUND: Changes in the receptor profile of primary breast cancers to their metastases (receptor conversion) have been described for the estrogen receptor α…”
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Genomic evolution from primary breast carcinoma to distant metastasis: Few copy number changes of breast cancer related genes by Moelans, Cathy B, van der Groep, Petra, Hoefnagel, Laurien D.C, van de Vijver, Marc J, Wesseling, Pieter, Wesseling, Jelle, van der Wall, Elsken, van Diest, Paul J

“…Abstract Cancer initiation and progression is characterized by (epi)genetic aberrations. However, little is known about the changes that occur during breast…”
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Upregulation of Claudin-4, CAIX and GLUT-1 in distant breast cancer metastases by Jiwa, Laura S, van Diest, Paul J, Hoefnagel, Laurien D, Wesseling, Jelle, Wesseling, Pieter, Moelans, Cathy B

“…Several studies have shown that the immunophenotype of distant breast cancer metastases may differ significantly from that of the primary tumor, especially…”
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Discordance in ERα, PR and HER2 receptor status across different distant breast cancer metastases within the same patient by Hoefnagel, L.D.C., van der Groep, P., van de Vijver, M.J., Boers, J.E., Wesseling, P., Wesseling, J., van der Wall, E., van Diest, P.J.

“…We studied discordance in estrogen receptor alpha (ERα), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) status between multiple…”
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The prognostic effect of DDX3 upregulation in distant breast cancer metastases by Heerma van Voss, Marise R., Schrijver, Willemijne A. M. E., ter Hoeve, Natalie D., Hoefnagel, Laurien D., Manson, Quirine F., van der Wall, Elsken, Raman, Venu, van Diest, Paul J.

“…Metastatic breast cancer remains one of the leading causes of death in women and identification of novel treatment targets is therefore warranted. Functional…”
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Influence of decalcification procedures on immunohistochemistry and molecular pathology in breast cancer by Schrijver, Willemijne A M E, van der Groep, Petra, Hoefnagel, Laurien DC, ter Hoeve, Natalie D, Peeters, Ton, Moelans, Cathy B, van Diest, Paul J

“…Distant breast cancer metastases are nowadays routinely biopsied to reassess receptor status and to isolate DNA for sequencing of druggable targets. Bone…”
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Testing for discordance at metastatic relapse of breast cancer matters by van Diest, Paul J, Hoefnagel, Laurien D C, van der Wall, Elsken

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OS06.6.A LOCAL DELIVERY OF HRBMP4 AS AN ANTICANCER THERAPY IN PATIENTS WITH RECURRENT GLIOBLASTOMA: A FIRST-IN-HUMAN PHASE 1 DOSE ESCALATION TRIAL by Bos, E M, Binda, E, Verploegh, I S, Wembacher, E, Hoefnagel, D, Balvers, R K, Korporaal, A L, Conidi, A, Warnert, E A H, Trivieri, N, Visioli, A, Zaccarini, P, Caiola, L, van Wijck, R, van der Spek, P, Huylebroeck, D, Leenstra, S, Lamfers, M L M, Ram, Z, Westphal, M, Noske, D, Legnani, F, DiMeco, F, Vescovi, A L, Dirven, C M F

“…Abstract BACKGROUND This Phase 1 study evaluates the intra- and peritumoral administration by convection enhanced delivery (CED) of human recombinant Bone…”
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Evidence for a genetic factor in the etiology of premature ovarian failure by Coulam, C B, Stringfellow, S, Hoefnagel, D

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Lesch-Nyhan syndrome. Pathology and pathologic physiology. Summary by Hoefnagel, D

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Chromosome abnormalities and genetic counselling by Hoefnagel, D

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Toxic effects of atropine and homatropine eyedrops in children by HOEFNAGEL, D

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Partial lipodystrophy and familial C3 deficiency by McLean, R H, Hoefnagel, D

“…A familial deficiency of C3 in the family of a patient with partial lipodystrophy is reported for the first time. This genetic defect is termed hypomorphism of…”
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Fulminating, rapidly fatal shigellosis in children by HOEFNAGEL, D

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Trisomy after colchicine therapy by Hoefnagel, D

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Dyscephalia Mandibulo-oculo-facialis by Hoefnagel, D., Benirschke, K.

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