Search Results - "Hoefman, Sven"

The more, the merrier: heterotroph richness stimulates methanotrophic activity by Ho, Adrian, de Roy, Karen, Thas, Olivier, De Neve, Jan, Hoefman, Sven, Vandamme, Peter, Heylen, Kim, Boon, Nico

“…Although microorganisms coexist in the same environment, it is still unclear how their interaction regulates ecosystem functioning. Using a methanotroph as a…”
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The preclinical pharmacology of the high affinity anti-IL-6R Nanobody® ALX-0061 supports its clinical development in rheumatoid arthritis by Van Roy, Maarten, Ververken, Cedric, Beirnaert, Els, Hoefman, Sven, Kolkman, Joost, Vierboom, Michel, Breedveld, Elia, 't Hart, Bert, Poelmans, Sofie, Bontinck, Lieselot, Hemeryck, Alex, Jacobs, Sandy, Baumeister, Judith, Ulrichts, Hans

“…The pleiotropic cytokine interleukin-6 (IL-6) plays an important role in the pathogenesis of different diseases, including rheumatoid arthritis (RA). ALX-0061…”
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Methylomonas lenta sp. nov., a methanotroph isolated from manure and a denitrification tank by Hoefman, Sven, Heylen, Kim, De Vos, Paul

“…Two methanotrophic bacteria, strains R-45377(T) and R-45370, were respectively isolated from a slurry pit of a cow stable and from a denitrification tank of a…”
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Niche differentiation in nitrogen metabolism among methanotrophs within an operational taxonomic unit by Hoefman, Sven, van der Ha, David, Boon, Nico, Vandamme, Peter, De Vos, Paul, Heylen, Kim

“…The currently accepted thesis on nitrogenous fertilizer additions on methane oxidation activity assumes niche partitioning among methanotrophic species, with…”
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Exploration and prediction of interactions between methanotrophs and heterotrophs by Stock, Michiel, Hoefman, Sven, Kerckhof, Frederiek-Maarten, Boon, Nico, De Vos, Paul, De Baets, Bernard, Heylen, Kim, Waegeman, Willem

“…Methanotrophs can form the basis of a methane-driven food web on which heterotrophic microorganisms can feed. In return, these heterotrophs can stimulate…”
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Population pharmacokinetics and pharmacodynamics of a novel vascular adhesion protein-1 inhibitor using a multiple-target mediated drug disposition model by Snelder, Nelleke, Hoefman, Sven, Garcia-Hernandez, Alberto, Onkels, Hartmut, Larsson, Tobias E., Bergmann, Kirsten R.

“…ASP8232 is a novel inhibitor of vascular adhesion protein-1 that was under evaluation for reducing residual albuminuria in patients with diabetic kidney…”
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Optimized cryopreservation of mixed microbial communities for conserved functionality and diversity by Kerckhof, Frederiek-Maarten, Courtens, Emilie N P, Geirnaert, Annelies, Hoefman, Sven, Ho, Adrian, Vilchez-Vargas, Ramiro, Pieper, Dietmar H, Jauregui, Ruy, Vlaeminck, Siegfried E, Van de Wiele, Tom, Vandamme, Peter, Heylen, Kim, Boon, Nico

“…The use of mixed microbial communities (microbiomes) for biotechnological applications has steadily increased over the past decades. However, these microbiomes…”
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Pre-Clinical Intravenous Serum Pharmacokinetics of Albumin Binding and Non-Half-Life Extended Nanobodies by Hoefman, Sven, Ottevaere, Ingrid, Baumeister, Judith, Sargentini-Maier, Maria

“…Nanobodies are antigen-binding, single variable domain proteins derived from naturally-occurring, heavy chain only antibodies. They are highly soluble, stable,…”
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Survival or revival: long-term preservation induces a reversible viable but non-culturable state in methane-oxidizing bacteria by Hoefman, Sven, Van Hoorde, Koenraad, Boon, Nico, Vandamme, Peter, De Vos, Paul, Heylen, Kim

“…Knowledge on long-term preservation of micro-organisms is limited and research in the field is scarce despite its importance for microbial biodiversity and…”
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Planktonic versus Biofilm Catabolic Communities: Importance of the Biofilm for Species Selection and Pesticide Degradation by VERHAGEN, Pieter, DE GELDER, Leen, HOEFMAN, Sven, DE VOS, Paul, BOON, Nico

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Mechanism-based modeling of the effect of a novel inhibitor of vascular adhesion protein-1 on albuminuria and renal function markers in patients with diabetic kidney disease by Hoefman, Sven, Snelder, Nelleke, van Noort, Martijn, Garcia-Hernandez, Alberto, Onkels, Hartmut, Larsson, Tobias E., Bergmann, Kirsten R.

“…The vascular adhesion protein-1 (VAP-1) inhibitor ASP8232 reduces albuminuria in patients with type 2 diabetes and chronic kidney disease. A mechanism-based…”
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Methyloparacoccus murrellii gen. nov., sp. nov., a methanotroph isolated from pond water by Hoefman, Sven, van der Ha, David, Iguchi, Hiroyuki, Yurimoto, Hiroya, Sakai, Yasuyoshi, Boon, Nico, Vandamme, Peter, Heylen, Kim, De Vos, Paul

“…Two novel methanotrophic strains, R-49797T and OS501, were isolated from pond water in South Africa and Japan, respectively. Strains R-49797T and OS501 shared…”
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A novel integrated QSP model of in vivo human glucose regulation to support the development of a glucagon/GLP‐1 dual agonist by Bosch, Rolien, Petrone, Marcella, Arends, Rosalin, Vicini, Paolo, Sijbrands, Eric J. G., Hoefman, Sven, Snelder, Nelleke

“…Glucagon‐like peptide‐1 (GLP‐1) receptor agonists (GLP‐1RAs) and dual GLP‐1/glucagon receptor agonists improve glycaemic control and cause significant weight…”
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Copper enhances the activity and salt resistance of mixed methane-oxidizing communities by van der Ha, David, Hoefman, Sven, Boeckx, Pascal, Verstraete, Willy, Boon, Nico

“…Effluents of anaerobic digesters are an underestimated source of greenhouse gases, as they are often saturated with methane. A post-treatment with…”
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Atmospheric methane removal by methane-oxidizing bacteria immobilized on porous building materials by Ganendra, Giovanni, De Muynck, Willem, Ho, Adrian, Hoefman, Sven, De Vos, Paul, Boeckx, Pascal, Boon, Nico

“…Biological treatment using methane-oxidizing bacteria (MOB) immobilized on six porous carrier materials have been used to mitigate methane emission…”
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Miniaturized extinction culturing is the preferred strategy for rapid isolation of fast‐growing methane‐oxidizing bacteria by Hoefman, Sven, van der Ha, David, De Vos, Paul, Boon, Nico, Heylen, Kim

“…Summary Methane‐oxidizing bacteria (MOB) have a large potential as a microbial sink for the greenhouse gas methane as well as for biotechnological purposes…”
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Characterisation of cotadutide's dual GLP‐1/glucagon receptor agonistic effects on glycaemic control using an in vivo human glucose regulation quantitative systems pharmacology model by Bosch, Rolien, Petrone, Marcella, Arends, Rosalin, Vicini, Paolo, Sijbrands, Eric J. G., Hoefman, Sven, Snelder, Nelleke

“…Background and Purpose Cotadutide is a dual GLP‐1 and glucagon receptor agonist with balanced agonistic activity at each receptor designed to harness the…”
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Population pharmacokinetics of regorafenib in solid tumours: Exposure in clinical practice considering enterohepatic circulation and food intake by Keunecke, Anne, Hoefman, Sven, Drenth, Henk‐Jan, Zisowsky, Jochen, Cleton, Adriaan, Ploeger, Bart A.

“…Aim Regorafenib is an oral multikinase inhibitor with clinical efficacy in a range of advanced solid tumours. A population pharmacokinetic (PK) model was…”
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Primers for overlooked nirK, qnorB, and nosZ genes of thermophilic Gram-positive denitrifiers by Verbaendert, Ines, Hoefman, Sven, Boeckx, Pascal, Boon, Nico, De Vos, Paul

“…Abstract Although efforts have been made the past few years, knowledge on genomic and phenotypic diversity and occurrence of the denitrification ability in…”
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Safeguarding bacterial resources promotes biotechnological innovation by Heylen, Kim, Hoefman, Sven, Vekeman, Bram, Peiren, Jindrich, De Vos, Paul

“…Environmental research delivers valuable bacterial resources for biotechnology. We believe that systematic long-term preservation of bacteria will promote…”
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