Search Results - "Hoefert, Sebastian"

Mechanical stress in plates for bridging reconstruction mandibular defects and purposes of double plate reinforcement by Hoefert, Sebastian, Taier, Roberto

“…To evaluate the biomechanical performance of a commercially available bridging plate (2.4) as well as screws and bone simulating the reconstruction of…”
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Routine panendoscopy in oral squamous cell cancer patients: mandatory or facultative? by Valentin, Anthony, Goetz, Martin, Hetzel, Juergen, Reinert, Siegmar, Hoefert, Sebastian

“…Objectives This study investigated benefits of routine panendoscopy in staging of oral squamous cell cancer patients. Materials and methods From 2013 to 2017,…”
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Relevance of a Prolonged Preoperative Antibiotic Regime in the Treatment of Bisphosphonate-Related Osteonecrosis of the Jaw by Hoefert, Sebastian, MD, DDS, Eufinger, Harald, MD, DDS, PhD

“…Purpose Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a severe and therapy-resistant disease. The present study was performed to evaluate the role…”
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Treatment response of advanced HNSCC towards immune checkpoint inhibition is associated with an activated effector memory T cell phenotype by Schumacher, Max, Beer, Sina, Moraes Ribeiro, Emmanuelle, Korkmaz, Fulya, Keppeler, Hildegard, Fitzel, Rahel, Erkner, Estelle, Radszuweit, Pia, Lengerke, Claudia, Schneidawind, Corina, Hoefert, Sebastian, Mauz, Paul Stefan, Schneidawind, Dominik

“…Locally advanced or metastatic head and neck squamous cell carcinoma (HNSCC) is associated with a poor prognosis. The introduction of PD-1 inhibitors has led…”
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Clinical course and therapeutic outcomes of operatively and non-operatively managed patients with denosumab-related osteonecrosis of the jaw (DRONJ) by Hoefert, Sebastian, Dr. Dr, Yuan, Anna, DMD, Postgraduate PhD, Munz, Adelheid, Grimm, Martin, PD Dr. Dr, Elayouti, Ashraf, PD Dr, Reinert, Siegmar, Prof. Dr. Dr

“…Abstract Purpose Details regarding risk factors, onset, and outcomes for denosumab-related osteonecrosis (DRONJ) are sparse. This study examines the clinical…”
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18F-Fluoride PET/CT Imaging of Medication-Related Osteonecrosis of the Jaw in Conservative Treatment—A Case Report by Reinert, Christian Philipp, Pfannenberg, Christina, Gatidis, Sergios, la Fougère, Christian, Nikolaou, Konstantin, Hoefert, Sebastian

“…Medication-related osteonecrosis of the jaw (MRONJ) is a serious side effect in antiresorptive treatment. Treatment of MRONJ is considered primarily…”
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Effect of bisphosphonates on macrophagic THP-1 cell survival in bisphosphonate-related osteonecrosis of the jaw (BRONJ) by Hoefert, Sebastian, MD, DMD, Sade Hoefert, Claudia, DMD, Munz, Adelheid, MTA, Schmitz, Inge, PhD, Grimm, Martin, MD, DMD, Yuan, Anna, DMD, Northoff, Hinnak, MD, PhD, Reinert, Siegmar, MD, DMD, Alexander, Dorothea, PhD

“…Objectives Immune deficiency and bacterial infection have been suggested to play a role in the pathophysiology of bisphosphonate-related osteonecrosis of the…”
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Importance of microcracks in etiology of bisphosphonate-related osteonecrosis of the jaw: a possible pathogenetic model of symptomatic and non-symptomatic osteonecrosis of the jaw based on scanning electron microscopy findings by Hoefert, Sebastian, Schmitz, Inge, Tannapfel, Andrea, Eufinger, Harald

“…The aim of this study was to evaluate a possible role of microcracks in the pathogenesis of bisphosphonate-related osteonecrosis of the jaw (ONJ) and to…”
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Sunitinib may raise the risk of bisphosphonate-related osteonecrosis of the jaw: presentation of three cases by Hoefert, Sebastian, MD, DDS, Eufinger, Harald, MD, DDS, PhD

“…Objective Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a serious side effect of bisphosphonate (BP) medication. Tooth extractions are the most…”
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Preoperative Assessment of Medication-Related Osteonecrosis of the Jaw Using [18F]fluoride Positron Emission Tomography (PET)/CT and [18F]fluorodeoxyglucose PET/MRI in Correlation with Histomorphometry and Micro-CT-A Prospective Comparative Study by Reinert, Christian Philipp, Pfannenberg, Christina, Gückel, Brigitte, Dittmann, Helmut, la Fougère, Christian, Nikolaou, Konstantin, Reinert, Siegmar, Schönhof, Rouven, Hoefert, Sebastian

“…The purpose of this study was to investigate the imaging characteristics of medication-related osteonecrosis of the jaw (MRONJ) using [18F]fluoride positron…”
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Co-expression of CD44+/RANKL+ tumor cells in the carcinogenesis of oral squamous cell carcinoma by Grimm, Martin, Renz, Cornelius, Munz, Adelheid, Hoefert, Sebastian, Krimmel, Michael, Reinert, Siegmar

“…[Abstract] Receptor activator of nuclear factor-kappa (RANK)/receptor activator of nuclear factor-kappa B ligand (RANKL) signaling helps putative cancer stem…”
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Transketolase-like protein 1 expression in recurrent oral squamous cell carcinoma after curative resection: a case report by Grimm, Martin, MD, DMD, Hoefert, Sebastian, MD, DMD, Luz, Oliver, MD, Reinert, Siegmar, MD, DMD, PhD, Polligkeit, Joachim, MD, DMD

“…Background Squamous cell carcinoma of the oral cavity (OSCC) is one of the common malignant tumors of the head and neck worldwide. Transketolase-like protein 1…”
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Change in reimbursement and costs in German oncological head and neck surgery over the last decade: ablative tongue cancer surgery and reconstruction with split-thickness skin graft vs. microvascular radial forearm flap by Hoefert, Sebastian, Lotter, Oliver

“…Objectives Defects after ablative tongue cancer surgery can be reconstructed by split-thickness skin grafts or free microvascular flaps. The different surgical…”
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Synthetic, non-person related panoramic radiographs created by generative adversarial networks in research, clinical, and teaching applications by Schoenhof, Rouven, Schoenhof, Raoul, Blumenstock, Gunnar, Lethaus, Bernd, Hoefert, Sebastian

“…Generative Adversarial Networks (GANs) can produce synthetic images free from personal data. They hold significant value in medical research, where data…”
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Gingival fibroblasts and medication-related osteonecrosis of the jaw: Results by real-time and wound healing in vitro assays by Yuan, Anna, Munz, Adelheid, Reinert, Siegmar, Hoefert, Sebastian

“…This study investigated the effects of bisphosphonates and denosumab on human gingival fibroblasts (HGFs) that could influence inflammation, wound healing, and…”
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Histologic analysis of medication-related osteonecrosis of the jaw compared with antiresorptive-exposed bone and other infectious, inflammatory, and necrotic jaw diseases by Yuan, Anna, Munz, Adelheid, Reinert, Siegmar, Hoefert, Sebastian

“…This study characterized histologic features of medication-related osteonecrosis of the jaw (MRONJ) through analysis of tissues from patients and healthy…”
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Microarchitecture of medication-related osteonecrosis of the jaw (MRONJ); a retrospective micro-CT and morphometric analysis by Schoenhof, Rouven, Munz, Adelheid, Yuan, Anna, ElAyouti, Ashraf, Boesmueller, Hans, Blumenstock, Gunnar, Reinert, Siegmar, Hoefert, Sebastian

“…Medication-related osteonecrosis of the jaw (MRONJ) is a severe side effect of antiresorptive (AR) drugs such as bisphosphonates (BP) and denosumab (Dmab)…”
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Macrophages and bisphosphonate-related osteonecrosis of the jaw (BRONJ): evidence of local immunosuppression of macrophages in contrast to other infectious jaw diseases by Hoefert, Sebastian, Schmitz, Inge, Weichert, Frank, Gaspar, Marcel, Eufinger, Harald

“…Objectives Bisphosphonates (BIP) are well established in bone diseases. A serious side effect is the bisphosphonate-related osteonecrosis of the jaw (BRONJ)…”
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Donor site morbidity of the anterolateral thigh flap by Weise, Hannes, Naros, Andreas, Blumenstock, Gunnar, Krimmel, Michael, Hoefert, Sebastian, Kluba, Susanne, Hofer, Stefan, Reinert, Siegmar

“…The purpose of this study was to investigate donor site morbidity after reconstruction of defects in the head and neck region with an anterolateral thigh (ALT)…”
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Three-dimensional accuracy of mandibular reconstruction by patient-specific pre-bent reconstruction plates using an “in-house” 3D-printer by Naros, Andreas, Weise, Hannes, Tilsen, Felix, Hoefert, Sebastian, Naros, Georgios, Krimmel, Michael, Reinert, Siegmar, Polligkeit, Joachim

“…The purpose of this study was to compare the three-dimensional accuracy of mandibular reconstruction following mandible continuity resection in patients…”
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