Search Results - "Hoed, M."

Genetic and metabolic determinants of methotrexate-induced mucositis in pediatric acute lymphoblastic leukemia by den Hoed, M A H, Lopez-Lopez, E, te Winkel, M L, Tissing, W, de Rooij, J D E, Gutierrez-Camino, A, Garcia-Orad, A, den Boer, E, Pieters, R, Pluijm, S M F, de Jonge, R, van den Heuvel-Eibrink, M M

“…Methotrexate (MTX) is an effective and toxic chemotherapeutic drug in the treatment of pediatric acute lymphoblastic leukemia(ALL). In this prospective study,…”
Get full text

Bone mineral density after childhood cancer in 346 long-term adult survivors of childhood cancer by den Hoed, M. A. H., Klap, B. C., te Winkel, M. L., Pieters, R., van Waas, M., Neggers, S. J. C. M. M., Boot, A. M., Blijdorp, K., van Dorp, W., Pluijm, S. M. F., van den Heuvel-Eibrink, M. M.

“…Summary More than 45 % of long-term childhood cancer survivors (CCS) were diagnosed with osteopenia. Our data suggest that greater awareness for osteopenia is…”
Get full text

Evaluation of ear, nose, and throat‐screening in liver transplantation candidates: A retrospective cohort study by Beukman, Eline, Meer, Adriaan J., Takkenberg, R. Bart, Hoed, Caroline M. den, Nagtegaal, Andries Paul

“…Background Patients with end‐stage liver disease can be treated with a liver transplantation (LT). Before listing, candidates are subjected to a screening…”
Get full text

Therapeutic drug monitoring of immunosuppressive drugs in hepatology and gastroenterology by Udomkarnjananun, Suwasin, Francke, Marith I., De Winter, Brenda C.M., Mulder, Midas B., Baan, Carla C., Metselaar, Herold J., den Hoed, Caroline M., Hesselink, Dennis A.

“…Immunosuppressive drugs have been key to the success of liver transplantation and are essential components of the treatment of inflammatory bowel disease (IBD)…”
Get full text

Ethnicity is a strong predictor for Helicobacter pylori infection in young women in a multi-ethnic European city by den Hollander, Wouter J, Holster, I Lisanne, den Hoed, Caroline M, van Deurzen, Frances, van Vuuren, Anneke J, Jaddoe, Vincent W, Hofman, Albert, Perez Perez, Guillermo I, Blaser, Martin J, Moll, Henriëtte A, Kuipers, Ernst J

“…Background and Aim At the same time that Helicobacter pylori prevalence is declining in Western countries, immigrants from developing countries with high H…”
Get full text

Current Perspectives on the Management of Herpesvirus Infections in Solid Organ Transplant Recipients by Malahe, S Reshwan K, van Kampen, Jeroen J A, Manintveld, Olivier C, Hoek, Rogier A S, den Hoed, Caroline M, Baan, Carla C, Kho, Marcia M L, Verjans, Georges M G M

“…Solid organ transplant recipients (SOTRs) are at high risk of human herpesvirus (HHV)-related morbidity and mortality due to the use of immunosuppressive…”
Get full text

Immunosuppressants exert differential effects on pan‐coronavirus infection and distinct combinatory antiviral activity with molnupiravir and nirmatrelvir by Wang, Yining, Li, Pengfei, Lavrijsen, Marla, Rottier, Robbert J., Hoed, Caroline M., Bruno, Marco J., Kamar, Nassim, Peppelenbosch, Maikel P., Vries, Annemarie C., Pan, Qiuwei

“…Background Immunocompromised populations, such as organ transplant recipients and patients with inflammatory bowel disease (IBD) receiving…”
Get full text

Highly conformable terahertz metasurface absorbers via two-photon polymerization on polymeric ultra-thin films by Ottomaniello, Andrea, Vezio, Paolo, Tricinci, Omar, Den Hoed, Frank M., Dean, Paul, Tredicucci, Alessandro, Mattoli, Virgilio

“…The continuously increasing interest in flexible and integrated photonics requires new strategies for device manufacturing on arbitrary complex surfaces and…”
Get full text

Accuracy of upper endoscopies with random biopsies to identify patients with gastric premalignant lesions who can safely be exempt from surveillance by Mommersteeg, Michiel C., Nieuwenburg, Stella A. V., den Hollander, Wouter J., Holster, Lisanne, den Hoed, Caroline M., Capelle, Lisette G., Tang, Tjon J., Anten, Marie- Paule, Prytz-Berset, Ingrid, Witteman, Ellen M., ter Borg, Frank, Burger, Jordy P. W., Doukas, Michail, Bruno, Marco J., Peppelenbosch, Maikel P., Fuhler, Gwenny M., Kuipers, Ernst J., Spaander, Manon C. W.

“…Introduction Guidelines recommend endoscopy with biopsies to stratify patients with gastric premalignant lesions (GPL) to high and low progression risk…”
Get full text

Evaluation of medication-related problems in liver transplant recipients with and without an outpatient medication consultation by a clinical pharmacist: a cohort study by Mulder, Midas B., Doga, B., Borgsteede, S. D., van den Burg, A. M., Metselaar, H. J., den Hoed, C. M., Hunfeld, N. G.M.

“…Background Transplant recipients undergo significant changes in their medication regimen during follow-up and are at an increased risk for medication-related…”
Get full text

Does dexamethasone induce more neuropsychological side effects than prednisone in pediatric acute lymphoblastic leukemia? A systematic review by Warris, L.T., van den Heuvel-Eibrink, M.M., den Hoed, M.A.H., Aarsen, F.K., Pieters, R., van den Akker, E.L.T.

“…Steroid‐induced neuropsychological side effects impact quality of life in children with acute lymphoblastic leukemia. Dexamethasone induces more metabolic side…”
Get full text

Oral antibiotics lower mycophenolate mofetil drug exposure, possibly by interfering with the enterohepatic recirculation: A case series by Simoons, Mirjam, Naipal, Kishan A. T., Jong, Huib, Hoed, Caroline M., Winter, Brenda C. M., Mulder, Midas B.

“…Mycophenolate mofetil has an important role as immunosuppressive agent in solid organ transplant recipients. Exposure to the active mycophenolic acid (MPA) can…”
Get full text

GWAS-identified loci for coronary heart disease are associated with intima-media thickness and plaque presence at the carotid artery bulb by den Hoed, Marcel, Strawbridge, Rona J, Almgren, Peter, Gustafsson, Stefan, Axelsson, Tomas, Engström, Gunnar, de Faire, Ulf, Hedblad, Bo, Humphries, Steve E, Lindgren, Cecilia M, Morris, Andrew P, Östling, Gerd, Syvänen, Ann-Christine, Tremoli, Elena, Hamsten, Anders, Ingelsson, Erik, Melander, Olle, Lind, Lars

“…Abstract Background Large-scale genome-wide association studies (GWAS) have so far identified 45 loci that are robustly associated with coronary heart disease…”
Get full text

Modifying Tacrolimus-related Toxicity After Liver Transplantation Comparing Life Cycle Pharma Tacrolimus Versus Extended-released Tacrolimus: A Multicenter, Randomized Controlled Trial by Mulder, Midas B, van Hoek, Bart, Polak, Wojtek G, Alwayn, Ian P J, de Winter, Brenda C M, Darwish Murad, Sarwa, Verhey-Hart, Elke, Elshove, Lara, Erler, Nicole S, Hesselink, Dennis A, den Hoed, Caroline M, Metselaar, Herold J

“…The aim of this open-label, multicenter, randomized controlled study was to investigate whether the life cycle pharma (LCP)-tacrolimus compared with the…”
Get full text

Pleiotropic effects of obesity-susceptibility loci on metabolic traits: a meta-analysis of up to 37,874 individuals by van Vliet-Ostaptchouk, J. V., den Hoed, M., Luan, J., Zhao, J. H., Ong, K. K., van der Most, P. J., Wong, A., Hardy, R., Kuh, D., van der Klauw, M. M., Bruinenberg, M., Khaw, K. T., Wolffenbuttel, B. H. R., Wareham, N. J., Snieder, H., Loos, R. J. F.

“…Aims/hypothesis Genetic pleiotropy may contribute to the clustering of obesity and metabolic conditions. We assessed whether genetic variants that are robustly…”
Get full text

Maternal diabetes and incidence of childhood cancer - a nationwide cohort study and exploratory genetic analysis by Deleskog, Anna, den Hoed, Marcel, Tettamanti, Giorgio, Carlsson, Sofia, Ljung, Rickard, Feychting, Maria, Brooke, Hannah L

“…The etiology of childhood cancer is not well understood, but may be linked to prenatal and perinatal factors, such as maternal diabetes. However, this…”
Get full text

Care for the organ transplant recipient on the intensive care unit by van den Hoogen, M.W.F., Seghers, L., Manintveld, O.C., Roest, S., Bekkers, J.A., den Hoed, C.M., Minnee, R.C., de Geus, H.R.H., van Thiel, R.J., Hesselink, D.A.

“…All transplant recipients receive tacrolimus, mycophenolate and glucocorticoids and these drugs have many side-effects and drug-drug interactions. Common…”
Get full text

Factors associated with the progression of gastric intestinal metaplasia: a multicenter, prospective cohort study by Nieuwenburg, S. A. V., Mommersteeg, M. C., Eikenboom, E. L., Yu, B., den Hollander, W. J., Holster, I. Lisanne, den Hoed, Caroline M., Capelle, L. G, Tang, Thjon J., Anten, Marie-Paule, Prytz-Berset, I., Witteman, E. M., ter Borg, F., Burger, Jordy P. W., Bruno, Marco J., Fuhler, G. M., Peppelenbosch, Maikel P., Doukas, Michael, Kuipers, Ernst J., Spaander, Manon C.W.

“…Abstract Background and study aims  Gastric cancer (GC) is usually preceded by premalignant gastric lesions (GPLs) such as gastric intestinal metaplasia (GIM)…”
Get full text

The prevalence of premalignant gastric lesions in asymptomatic patients: Predicting the future incidence of gastric cancer by den Hoed, C.M, van Eijck, B.C, Capelle, L.G, van Dekken, H, Biermann, K, Siersema, P.D, Kuipers, E.J

“…Abstract Background Helicobacter pylori is the main risk-factor for gastric cancer through a cascade from gastritis through atrophic gastritis (AG), intestinal…”
Get full text

Dysregulation of macrophage PEPD in obesity determines adipose tissue fibro-inflammation and insulin resistance by Pellegrinelli, V., Rodriguez-Cuenca, S., Rouault, C., Figueroa-Juarez, E., Schilbert, H., Virtue, S., Moreno-Navarrete, J. M., Bidault, G., Vázquez-Borrego, M. C., Dias, A. R., Pucker, B., Dale, M., Campbell, M., Carobbio, S., Lin, Y. H., Vacca, M., Aron-Wisnewsky, J., Mora, S., Masiero, M. M., Emmanouilidou, A., Mukhopadhyay, S., Dougan, G., den Hoed, M., Loos, R. J. F., Fernández-Real, J. M., Chiarugi, D., Clément, K., Vidal-Puig, A.

“…Resulting from impaired collagen turnover, fibrosis is a hallmark of adipose tissue (AT) dysfunction and obesity-associated insulin resistance (IR). Prolidase,…”
Get full text