Search Results - "Hoeben, Freek J. M."
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Bioorthogonal Tetrazine Carbamate Cleavage by Highly Reactive trans-Cyclooctene
Published in Journal of the American Chemical Society (24-06-2020)“…The high rate of the ‘click-to-release’ reaction between an allylic substituted trans-cyclooctene linker and a tetrazine activator has enabled exceptional…”
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Triggered Drug Release from an Antibody–Drug Conjugate Using Fast “Click-to-Release” Chemistry in Mice
Published in Bioconjugate chemistry (20-07-2016)“…The use of a bioorthogonal reaction for the selective cleavage of tumor-bound antibody–drug conjugates (ADCs) would represent a powerful new tool for ADC…”
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Supramolecular p−n-Heterojunctions by Co-Self-Organization of Oligo(p-phenylene Vinylene) and Perylene Bisimide Dyes
Published in Journal of the American Chemical Society (01-09-2004)“…Comparative studies on hydrogen-bonded versus covalently linked donor−acceptor−donor dye arrays obtained from oligo(p-phenylene vinylene)s (OPVs) as donor and…”
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Influence of Supramolecular Organization on Energy Transfer Properties in Chiral Oligo(p-phenylene vinylene) Porphyrin Assemblies
Published in Journal of the American Chemical Society (08-08-2007)“…A comparative study on oligo(p-phenylene vinylene) (OPV)-appended porphyrins containing all trans-vinylene (either hydrophilic or lipophilic) or amide linkages…”
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Surface-Induced Diastereomeric Complex Formation of a Nucleoside at the Liquid/Solid Interface: Stereoselective Recognition and Preferential Adsorption
Published in Journal of the American Chemical Society (03-07-2013)“…With the aim of achieving surface-mediated enantioselective adsorption, the self-assembly of chiral oligo(p-phenylenevinylene) (OPV3T) with nucleosides is…”
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About Supramolecular Assemblies of π-Conjugated Systems
Published in Chemical reviews (01-04-2005)“…Hoeben et al want to bring together the areas of supramolecular assembly and pi-conjugated systems. Hoeben et al focus on the self-assembly and properties of…”
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Sequential Energy and Electron Transfer in Aggregates of Tetrakis[oligo(p-phenylene vinylene)] Porphyrins and C60 in Water
Published in Journal of the American Chemical Society (05-10-2005)“…Chiral aggregation of oligo(p-phenylene vinylene)-functionalized Zn and free-base porphyrins is observed in water. The formation of mixed assemblies containing…”
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Visualization of Various Supramolecular Assemblies of Oligo(para-phenylenevinylene)-Melamine and Perylene Bisimide
Published in Chemistry : a European journal (26-09-2008)“…A melamine derivative has been covalently equipped with two oligo(para‐phenylenevinylene) (OPV) chromophores. This procedure yields a bifunctional molecule…”
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Chiral Alignment of OPV Chromophores: Exploitation of the Ureidophthalimide-Based Foldamer
Published in Journal of the American Chemical Society (20-12-2006)“…The ability of foldamers to adopt a secondary structure in solution has been exploited to organize peripheral functionality. Our previously reported…”
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Metal-Free Cycloaddition Chemistry Driven Pretargeted Radioimmunotherapy Using α‑Particle Radiation
Published in Bioconjugate chemistry (20-12-2017)“…The pretargeted radioimmunotherapy approach (PRIT) decouples the administration of tumor targeting monoclonal antibodies (mAbs) from that of the radiolabeled…”
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DOTA-tetrazine probes with modified linkers for tumor pretargeting
Published in Nuclear medicine and biology (01-12-2017)“…Pretargeted radioimmunoimaging and -therapy approaches building on the bioorthogonal inverse-electron-demand Diels–Alder (IEDDA) reaction between strained…”
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Scaling Behavior of Dendritic Nanoparticle Mobility in Semidilute Polymer Solutions
Published in Macromolecules (27-10-2015)“…In our studies on particle mobility in polymer solutions, we have investigated and determined self-diffusion coefficients of nanoparticles in semidilute…”
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Toward Single-Enzyme Molecule Electrochemistry: [NiFe]-Hydrogenase Protein Film Voltammetry at Nanoelectrodes
Published in ACS nano (23-12-2008)“…We have scaled down electrochemical assays of redox-active enzymes enabling us to study small numbers of molecules. Our approach is based on lithographically…”
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NMR Nanoparticle Diffusometry in Hydrogels: Enhancing Sensitivity and Selectivity
Published in Analytical chemistry (Washington) (16-09-2014)“…From the diffusional behavior of nanoparticles in heterogeneous hydrogels, quantitative information about submicron structural features of the polymer matrix…”
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Molecular-Level Helical Stack of a Nucleotide-Appended Oligo(p-phenylenevinylene) Directed by Supramolecular Self-Assembly with a Complementary Oligonucleotide as a Template
Published in Journal of the American Chemical Society (11-10-2006)“…The nucleotide-appended oligo(p-phenylenevinylene),…”
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Complex Coacervate Core Micelles with Spectroscopic Labels for Diffusometric Probing of Biopolymer Networks
Published in Langmuir (24-11-2015)“…We present the design, preparation, and characterization of two types of complex coacervate core micelles (C3Ms) with cross-linked cores and spectroscopic…”
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Transfer of π-Conjugated Columnar Stacks from Solution to Surfaces
Published in Journal of the American Chemical Society (24-12-2003)“…Three hydrogen-bonded oligo(p-phenylenevinylene)s, OPV3, OPV4, and OPV5, that differ in conjugation length have been synthesized and fully characterized. All…”
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Investigating the Cellular Specificity in Tumors of a Surface-Converting Nanoparticle by Multimodal Imaging
Published in Bioconjugate chemistry (17-05-2017)“…Active targeting of nanoparticles through surface functionalization is a common strategy to enhance tumor delivery specificity. However, active targeting…”
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Fluorescence‐ and multispectral optoacoustic imaging for an optimized detection of deeply located tumors in an orthotopic mouse model of pancreatic carcinoma
Published in International journal of cancer (15-05-2018)“…A crucial point for the management of pancreatic ductal adenocarcinoma (PDAC) is the decrease of R1 resections. Our aim was to evaluate the combination of…”
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Direct Visualization of Efficient Energy Transfer in Single Oligo(p-phenylene vinylene) Vesicles
Published in Angewandte Chemie International Edition (13-02-2006)“…Monitoring self‐assembled objects: Optical studies and scanning confocal microscopy have been used to monitor intermolecular energy transfer (ENT) in mixed…”
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