Search Results - "Hoe Chow, Pierce Kah"

Tumor‐adjacent tissue co‐expression profile analysis reveals pro‐oncogenic ribosomal gene signature for prognosis of resectable hepatocellular carcinoma by Grinchuk, Oleg V., Yenamandra, Surya P., Iyer, Ramakrishnan, Singh, Malay, Lee, Hwee Kuan, Lim, Kiat Hon, Chow, Pierce Kah‐Hoe, Kuznetsov, Vladamir A.

“…Currently, molecular markers are not used when determining the prognosis and treatment strategy for patients with hepatocellular carcinoma (HCC). In the…”
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Global Epidemiology and Genetics of Hepatocellular Carcinoma by Toh, Ming Ren, Wong, Evelyn Yi Ting, Wong, Sunny Hei, Ng, Alvin Wei Tian, Loo, Lit-Hsin, Chow, Pierce Kah-Hoe, Ngeow, Joanne

“…Hepatocellular carcinoma (HCC) is one of the leading cancers worldwide. Classically, HCC develops in genetically susceptible individuals who are exposed to…”
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Splice‐switch oligonucleotide‐based combinatorial platform prioritizes synthetic lethal targets CHK1 and BRD4 against MYC‐driven hepatocellular carcinoma by Thng, Dexter Kai Hao, Toh, Tan Boon, Pigini, Paolo, Hooi, Lissa, Dan, Yock Young, Chow, Pierce Kah‐Hoe, Bonney, Glenn Kunnath, Rashid, Masturah Bte Mohd Abdul, Guccione, Ernesto, Wee, Dave Keng Boon, Chow, Edward Kai‐Hua

“…Deregulation of MYC is among the most frequent oncogenic drivers in hepatocellular carcinoma (HCC). Unfortunately, the clinical success of MYC‐targeted…”
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Development of a new patient-derived xenograft humanised mouse model to study human-specific tumour microenvironment and immunotherapy by Zhao, Yue, Shuen, Timothy Wai Ho, Toh, Tan Boon, Chan, Xue Ying, Liu, Min, Tan, Sue Yee, Fan, Yong, Yang, Hechuan, Lyer, Shridhar Ganpathi, Bonney, Glenn Kunnath, Loh, Eva, Chang, Kenneth Tou En, Tan, Thiam Chye, Zhai, Weiwei, Chan, Jerry Kok Yen, Chow, Edward Kai-Hua, Chee, Cheng Ean, Lee, Guan Huei, Dan, Yock Young, Chow, Pierce Kah-Hoe, Toh, Han Chong, Lim, Seng Gee, Chen, Qingfeng

“…As the current therapeutic strategies for human hepatocellular carcinoma (HCC) have been proven to have limited effectiveness, immunotherapy becomes a…”
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Over-expression of the mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK in hepatocellular carcinoma: its role in tumor progression and apoptosis by Huynh, Hung, Nguyen, Thi Thanh Tuyen, Chow, Kah-Hoe Pierce, Tan, Puay Hoon, Soo, Khee Chee, Tran, Evelyne

“…Hepatocellular carcinoma (HCC) is one of the most common malignancies in South East Asia. Although activation of the MEK-MAPK is often associated with cellular…”
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Microvascular Invasion Is a Better Predictor of Tumor Recurrence and Overall Survival Following Surgical Resection for Hepatocellular Carcinoma Compared to the Milan Criteria by LIM, Kheng-Choon, CHOW, Pierce Kah-Hoe, ALLEN, John C, CHIA, Ghim-Song, LIM, Miaoshan, CHEOW, Peng-Chung, CHUNG, Alexander Y. F, OOI, London L. P, TAN, Say-Beng

“…To compare microvascular invasion (McVI) with parameters defined by the Milan criteria in predicting tumor recurrence and overall survival (OS) in patients…”
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The spatial organization of intra-tumour heterogeneity and evolutionary trajectories of metastases in hepatocellular carcinoma by Zhai, Weiwei, Lim, Tony Kiat-Hon, Zhang, Tong, Phang, Su-Ting, Tiang, Zenia, Guan, Peiyong, Ng, Ming-Hwee, Lim, Jia Qi, Yao, Fei, Li, Zheng, Ng, Poh Yong, Yan, Jie, Goh, Brian K., Chung, Alexander Yaw-Fui, Choo, Su-Pin, Khor, Chiea Chuen, Soon, Wendy Wei-Jia, Sung, Ken Wing-Kin, Foo, Roger Sik-Yin, Chow, Pierce Kah-Hoe

“…Hepatocellular carcinoma (HCC) has one of the poorest survival rates among cancers. Using multi-regional sampling of nine resected HCC with different…”
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Three-Dimensional Aggregated Spheroid Model of Hepatocellular Carcinoma Using a 96-Pillar/Well Plate by Lee, Sang-Yun, Teng, Yvonne, Son, Miseol, Ku, Bosung, Hwang, Hyun Ju, Tergaonkar, Vinay, Chow, Pierce Kah-Hoe, Lee, Dong Woo, Nam, Do-Hyun

“…A common method of three-dimensional (3D) cell cultures is embedding single cells in Matrigel. Separated cells in Matrigel migrate or grow to form spheroids…”
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High-dose drug heat map analysis for drug safety and efficacy in multi-spheroid brain normal cells and GBM patient-derived cells by Lee, Sang-Yun, Teng, Yvonne, Son, Miseol, Ku, Bosung, Moon, Ho Sang, Tergaonkar, Vinay, Chow, Pierce Kah-Hoe, Lee, Dong Woo, Nam, Do-Hyun

“…To test the safety and efficacy of drugs via a high does drug heat map, a multi-spheroids array chip was developed by adopting a micropillar and microwell…”
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Grit protects medical students from burnout: a longitudinal study by Jumat, Muhammad Raihan, Chow, Pierce Kah-Hoe, Allen, Jr, John Carson, Lai, Siang Hui, Hwang, Nian-Chih, Iqbal, Jabed, Mok, May Un Sam, Rapisarda, Attilio, Velkey, John Matthew, Engle, Deborah Lynn, Compton, Scott

“…Burnout is a serious issue plaguing the medical profession with potential negative consequences on patient care. Burnout symptoms are observed as early as…”
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Hepatic FTO expression is increased in NASH and its silencing attenuates palmitic acid-induced lipotoxicity by Lim, Andrea, Zhou, Jin, Sinha, Rohit A., Singh, Brijesh K., Ghosh, Sujoy, Lim, Kiat-Hon, Chow, Pierce Kah-Hoe, Woon, Esther C.Y., Yen, Paul M.

“…Non-alcoholic steatohepatitis (NASH) is one of the most common causes of liver failure worldwide. It is characterized by excess fat accumulation, inflammation,…”
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Comprehensive analysis of transcriptome profiles in hepatocellular carcinoma by Jin, Yu, Lee, Wai Yeow, Toh, Soo Ting, Tennakoon, Chandana, Toh, Han Chong, Chow, Pierce Kah-Hoe, Chung, Alexander Y-F, Chong, Samuel S, Ooi, London L-P-J, Sung, Wing-Kin, Lee, Caroline G-L

“…Hepatocellular carcinoma is the second most deadly cancer with late presentation and limited treatment options, highlighting an urgent need to better…”
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Utility of combining PIVKA-II and AFP in the surveillance and monitoring of hepatocellular carcinoma in the Asia-Pacific region by Kim, Do Young, Toan, Bao Nguyen, Tan, Chee-Kiat, Hasan, Irsan, Setiawan, Lyana, Yu, Ming-Lung, Izumi, Namiki, Huyen, Nguyen Nguyen, Chow, Pierce Kah-Hoe, Mohamed, Rosmawati, Chan, Stephen Lam, Tanwandee, Tawesak, Lee, Teng-Yu, Hai, Thi Thanh Nguyen, Yang, Tian, Lee, Woo-Chang, Chan, Henry Lik Yuen

“…Even though the combined use of ultrasound (US) and alpha-fetoprotein (AFP) is recommended for the surveillance of hepatocellular carcinoma (HCC), the…”
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A review of prognostic scores after liver resection in hepatocellular carcinoma: the MSKCC, SLICER and SSCLIP scores by Chan, Esther Ern-Hwei, Chow, Pierce Kah-Hoe

“…Predicting prognosis in hepatocellular carcinoma (HCC) aids clinical decision-making and stratifies patient follow-up plans. There are currently three…”
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Resection for hepatocellular carcinoma: Is it justifiable to restrict this to the American Association for the Study of the Liver/Barcelona Clinic for Liver Cancer criteria? by Chow, Pierce Kah-Hoe

“…Hepatocellular carcinoma (HCC) is an important cancer worldwide. The main curative treatment modality is surgical resection although only a minority of…”
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Transferrin-conjugated magnetic silica PLGA nanoparticles loaded with doxorubicin and paclitaxel for brain glioma treatment by Cui, Yanna, Xu, Qingxing, Chow, Pierce Kah-Hoe, Wang, Deping, Wang, Chi-Hwa

“…Abstract The effective treatment of malignant brain glioma is hindered by the poor transport across the blood–brain barrier (BBB) and the low penetration…”
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Consensus for Radiotherapy in Hepatocellular Carcinoma from The 5th Asia-Pacific Primary Liver Cancer Expert Meeting (APPLE 2014): Current Practice and Future Clinical Trials by Park, Hee Chul, Yu, Jeong Il, Cheng, Jason Chia-Hsien, Zeng, Zhao Chong, Hong, Ji Hong, Wang, Michael Lian Chek, Kim, Mi Sook, Chi, Kwan Hwa, Liang, Po-Ching, Lee, Rheun-Chuan, Lau, Wan-Yee, Han, Kwang Hyub, Chow, Pierce Kah-Hoe, Seong, Jinsil

“…A consensus meeting to develop practice guidelines and to recommend future clinical trials for radiation therapy (RT), including external beam RT (EBRT), and…”
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Recurrent Dermatofibrosarcoma Protuberans of the Shoulder with Rare Distant Abdominal Metastasis detected by Fluorodeoxyglucose-Positron Emission Tomography - Computed Tomography ( FDG-PET / CT ) by Pierce , Chow Kah Hoe, Zaheer , Sumbul, Sittampalam , Kesavan, Al-Tamimi , Ammad, Osmany , Saabry

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An appraisal of surgical and percutaneous drainage for pyogenic liver abscesses larger than 5 cm by TAN, Yu-Meng, CHUNG, Alexander Yaw-Fui, CHOW, Pierce Kah-Hoe, CHEOW, Peng-Chung, WONG, Wai-Keong, LONDON LUCIEN OOI, SOO, Khee-Chee

“…To determine whether first-line treatment with percutaneous or surgical drainage of liver abscesses larger than 5 cm results in better clinical outcome…”
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Current role of selective internal radiation with yttrium-90 in liver tumors by Lau, Wan Yee, Teoh, Yee Leong, Win, Khin Maung, Lee, Rheun-Chuan, de Villa, Vanessa H, Kim, Yun Hwan Joseph, Liang, Po-Chin, Santos-Ocampo, Ramon S, Lo, Richard Hoau Gong, Lim, Kieron Boon Leng, Tai, David Wai Meng, Ng, David Chee Eng, Irani, Farah Gillan, Gogna, Apoorva, Chow, Pierce Kah-Hoe

“…An expert panel met to review the evidence for selective internal radiation therapy (SIRT) using yttrium-90 microspheres in hepatocellular carcinoma and…”
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