Search Results - "Hoe, Kwang Lae"

CSNK1G2 differently sensitizes tamoxifen-induced decrease in PI3K/AKT/mTOR/S6K and ERK signaling according to the estrogen receptor existence in breast cancer cells by Nguyen Hoang, Anh Thu, Hoe, Kwang-Lae, Lee, Sook-Jeong

“…Tamoxifen (TAM) is a selective estrogen receptor modulator used for breast cancer patients. Prolonged use of tamoxifen is not recommended for some patients. In…”
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Conservation and Rewiring of Functional Modules Revealed by an Epistasis Map in Fission Yeast by Roguev, Assen, Bandyopadhyay, Sourav, Zofall, Martin, Zhang, Ke, Fischer, Tamas, Collins, Sean R, Qu, Hongjing, Shales, Michael, Park, Han-Oh, Hayles, Jacqueline, Hoe, Kwang-Lae, Kim, Dong-Uk, Ideker, Trey, Grewal, Shiv I, Weissman, Jonathan S, Krogan, Nevan J

“…An epistasis map (E-MAP) was constructed in the fission yeast, Schizosaccharomyces pombe, by systematically measuring the phenotypes associated with pairs of…”
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A genome-wide resource of cell cycle and cell shape genes of fission yeast by Hayles, Jacqueline, Wood, Valerie, Jeffery, Linda, Hoe, Kwang-Lae, Kim, Dong-Uk, Park, Han-Oh, Salas-Pino, Silvia, Heichinger, Christian, Nurse, Paul

“…To identify near complete sets of genes required for the cell cycle and cell shape, we have visually screened a genome-wide gene deletion library of 4843…”
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Stc1: A Critical Link between RNAi and Chromatin Modification Required for Heterochromatin Integrity by Bayne, Elizabeth H., White, Sharon A., Kagansky, Alexander, Bijos, Dominika A., Sanchez-Pulido, Luis, Hoe, Kwang-Lae, Kim, Dong-Uk, Park, Han-Oh, Ponting, Chris P., Rappsilber, Juri, Allshire, Robin C.

“…In fission yeast, RNAi directs heterochromatin formation at centromeres, telomeres, and the mating type locus. Noncoding RNAs transcribed from repeat elements…”
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Identification of Rbd2 as a candidate protease for sterol regulatory element binding protein (SREBP) cleavage in fission yeast by Kim, Jinsil, Ha, Hye-Jeong, Kim, Sujin, Choi, Ah-Reum, Lee, Sook-Jeong, Hoe, Kwang-Lae, Kim, Dong-Uk

“…Lipid homeostasis in mammalian cells is regulated by sterol regulatory element-binding protein (SREBP) transcription factors that are activated through…”
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Genome-wide functional analysis using the barcode sequence alignment and statistical analysis (Barcas) tool by Mun, Jihyeob, Kim, Dong-Uk, Hoe, Kwang-Lae, Kim, Seon-Young

“…Pooled library screen analysis using shRNAs or CRISPR-Cas9 hold great promise to genome-wide functional studies. While pooled library screens are effective…”
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G-749 Promotes Receptor Tyrosine Kinase TYRO3 Degradation and Induces Apoptosis in Both Colon Cancer Cell Lines and Xenograft Mouse Models by Kim, Hae Dong, Park, Eun Jung, Choi, Eun Kyoung, Song, Seuk Young, Hoe, Kwang-Lae, Kim, Dong-Uk

“…G-749 is an FLT3 kinase inhibitor that was originally developed as a treatment for acute myeloid leukemia. Some FLT3 kinase inhibitors are dual kinase…”
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Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes by Dixon, Scott J, Fedyshyn, Yaroslav, Koh, Judice L.Y, Prasad, T.S. Keshava, Chahwan, Charly, Chua, Gordon, Toufighi, Kiana, Baryshnikova, Anastasija, Hayles, Jacqueline, Hoe, Kwang-Lae, Kim, Dong-Uk, Park, Han-Oh, Myers, Chad L, Pandey, Akhilesh, Durocher, Daniel, Andrews, Brenda J, Boone, Charles

“…Synthetic lethal genetic interaction networks define genes that work together to control essential functions and have been studied extensively in Saccharomyces…”
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Yeast SREBP Cleavage Activation Requires the Golgi Dsc E3 Ligase Complex by Stewart, Emerson V., Nwosu, Christine C., Tong, Zongtian, Roguev, Assen, Cummins, Timothy D., Kim, Dong-Uk, Hayles, Jacqueline, Park, Han-Oh, Hoe, Kwang-Lae, Powell, David W., Krogan, Nevan J., Espenshade, Peter J.

“…Mammalian lipid homeostasis requires proteolytic activation of membrane-bound sterol regulatory element binding protein (SREBP) transcription factors through…”
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The fission yeast GATA factor, Gaf1, modulates sexual development via direct down-regulation of ste11+ expression in response to nitrogen starvation by Kim, Lila, Hoe, Kwang-Lae, Yu, Yeong Man, Yeon, Ji-Hyun, Maeng, Pil Jae

“…Gaf1 is the first GATA family zinc-finger transcription factor identified in Schizosaccharomyces pombe. Here, we report that Gaf1 functions as a negatively…”
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Arginase II activity regulates cytosolic Ca2+ level in a p32-dependent manner that contributes to Ca2+-dependent vasoconstriction in native low-density lipoprotein-stimulated vascular smooth muscle cells by Koo, Bon-hyeock, Hong, Dongeui, Hong, Hyeon Don, Lim, Hyun Kyo, Hoe, Kwang Lae, Won, Moo-Ho, Kim, Young Myeong, Berkowitz, Dan E., Ryoo, Sungwoo

“…Although arginase II (ArgII) is abundant in mitochondria, Ca 2+ -accumulating organelles, the relationship between ArgII activity and Ca 2+ translocation into…”
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Mitochondrial dysfunction increases oxidative stress and decreases chronological life span in fission yeast by Zuin, Alice, Gabrielli, Natalia, Calvo, Isabel A, García-Santamarina, Sarela, Hoe, Kwang-Lae, Kim, Dong Uk, Park, Han-Oh, Hayles, Jacqueline, Ayté, José, Hidalgo, Elena

“…Oxidative stress is a probable cause of aging and associated diseases. Reactive oxygen species (ROS) originate mainly from endogenous sources, namely the…”
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Systematic Target Screening Revealed That Tif302 Could Be an Off-Target of the Antifungal Terbinafine in Fission Yeast by Lee, Sol, Nam, Miyoung, Lee, Ah-Reum, Lee, Jaewoong, Woo, Jihye, Kang, Nam Sook, Balupuri, Anand, Lee, Minho, Kim, Seon-Young, Ro, Hyunju, Choi, Youn-Woong, Kim, Dong-Uk, Hoe, Kwang-Lae

“…We used a heterozygous gene deletion library of fission yeasts comprising all essential and non-essential genes for a microarray screening of target genes of…”
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The CCR4-NOT complex is implicated in the viability of aneuploid yeasts by Tange, Yoshie, Kurabayashi, Atsushi, Goto, Bunshiro, Hoe, Kwang-Lae, Kim, Dong-Uk, Park, Han-Oh, Hayles, Jacqueline, Chikashige, Yuji, Tsutumi, Chihiro, Hiraoka, Yasushi, Yamao, Fumiaki, Nurse, Paul, Niwa, Osami

“…To identify the genes required to sustain aneuploid viability, we screened a deletion library of non-essential genes in the fission yeast Schizosaccharomyces…”
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S. pombe genome deletion project: An update by Spirek, Mario, Benko, Zsigmond, Carnecka, Martina, Rumpf, Cornelia, Cipak, Lubos, Batova, Monika, Marova, Ivana, Nam, Miyoung, Kim, Dong-Uk, Park, Han-Oh, Hayles, Jacqueline, Hoe, Kwang-Lae, Nurse, Paul, Gregan, Juraj

“…The fission yeast Schizosaccharomyces pombe is a model organism used widely to study various aspects of eukaryotic biology. A collection of heterozygous…”
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Chronic peripheral administration of the angiotensin II AT1 receptor antagonist Candesartan blocks brain AT1 receptors by Nishimura, Yasuaki, Ito, Takeshi, Hoe, Kwang-Lae, Saavedra, Juan M.

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Optimization of a microarray for fission yeast by Kim, Dong-Uk, Lee, Minho, Han, Sangjo, Nam, Miyoung, Lee, Sol, Lee, Jaewoong, Woo, Jihye, Kim, Dongsup, Hoe, Kwang-Lae

“…Bar-code (tag) microarrays of yeast gene-deletion collections facilitate the systematic identification of genes required for growth in any condition of…”
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Peripheral Administration of an Angiotensin II AT1 Receptor Antagonist Decreases the Hypothalamic-Pituitary-Adrenal Response to Isolation Stress by Armando, Ines, Carranza, Andrea, Nishimura, Yasuaki, Hoe, Kwang-Lae, Barontini, Marta, Terrón, José A, Falcón-Neri, Alicia, Ito, Takeshi, Juorio, Augusto V, Saavedra, Juan M

“…Angiotensin II, which stimulates AT1 receptors, is a brain and peripheral stress hormone. We pretreated rats with the AT1 receptor antagonist candesartan for…”
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Nsk1 ensures accurate chromosome segregation by promoting association of kinetochores to spindle poles during anaphase B by Buttrick, Graham J, Meadows, John C, Lancaster, Theresa C, Vanoosthuyse, Vincent, Shepperd, Lindsey A, Hoe, Kwang-Lae, Kim, Dong-Uk, Park, Han-Oh, Hardwick, Kevin G, Millar, Jonathan B A

“…Type 1 phosphatase (PP1) antagonizes Aurora B kinase to stabilize kinetochore-microtubule attachments and to silence the spindle checkpoint. We screened for…”
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Systematic Target Screening Revealed That Tif302 Could Be an Off-Target of the Antifungal Terbinafine in Fission Yeast by Lee, Sol, Nam, Miyoung, Lee, Ah-Reum, Lee, Jaewoong, Woo, Jihye, Kang, Nam Sook, Balupuri, Anand, Lee, Minho, Kim, Seon-Young, Ro, Hyunju, Choi, Youn-Woong, Kim, Dong-Uk, Hoe, Kwang-Lae

“…We used a heterozygous gene deletion library of fission yeasts comprising all essential and non-essential genes for a microarray screening of target genes of…”
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