Search Results - "Hodin, Caroline M"

Regulated Proteolysis of NOTCH2 and NOTCH3 Receptors by ADAM10 and Presenilins by Groot, Arjan J., Habets, Roger, Yahyanejad, Sanaz, Hodin, Caroline M., Reiss, Karina, Saftig, Paul, Theys, Jan, Vooijs, Marc

“…In mammals, there are four NOTCH receptors and five Delta-Jagged-type ligands regulating many aspects of embryonic development and adult tissue homeostasis…”
Get full text

Hemolysis results in impaired intestinal microcirculation and intestinal epithelial cell injury by Hanssen, Sebastiaan J, Lubbers, Tim, Hodin, Caroline M, Prinzen, Frits W, Buurman, Wim A, Jacobs, Michael J

“…AIM：To study the effect of circulating cell-free oxy-hemoglobin（FHb） on intestinal microcirculation and intestinal epithelial injury in a rat model. METHODS：To…”
Get full text

Starvation Compromises Paneth Cells by Hodin, Caroline M, Lenaerts, Kaatje, Grootjans, Joep, de Haan, Jacco J, Hadfoune, M'hamed, Verheyen, Fons K, Kiyama, Hiroshi, Heineman, Erik, Buurman, Wim A

“…Lack of enteral feeding, with or without parenteral nutritional support, is associated with increased intestinal permeability and translocation of bacteria…”
Get full text

Level of Activation of the Unfolded Protein Response Correlates With Paneth Cell Apoptosis in Human Small Intestine Exposed to Ischemia/Reperfusion by Grootjans, Joep, Hodin, Caroline M, de Haan, Jacco–Juri, Derikx, Joep P.M, Rouschop, Kasper M.A, Verheyen, Fons K, van Dam, Ronald M, Dejong, Cornelis H.C, Buurman, Wim A, Lenaerts, Kaatje

“…Background & Aims In the intestine, Paneth cells participate in the innate immune response. Their highly secretory function makes them susceptible to…”
Get full text

Reduced Paneth cell antimicrobial protein levels correlate with activation of the unfolded protein response in the gut of obese individuals by Hodin, Caroline M, Verdam, Froukje J, Grootjans, Joep, Rensen, Sander S, Verheyen, Fons K, Dejong, Cornelis HC, Buurman, Wim A, Greve, Jan Willem, Lenaerts, Kaatje

“…The intestinal microbiota is increasingly acknowledged to play a crucial role in the development of obesity. A shift in intestinal microbiota composition…”
Get full text

Total parenteral nutrition induces a shift in the Firmicutes to Bacteroidetes ratio in association with Paneth cell activation in rats by Hodin, Caroline M, Visschers, Ruben G J, Rensen, Sander S, Boonen, Bas, Olde Damink, Steven W M, Lenaerts, Kaatje, Buurman, Wim A

“…The use of total parenteral nutrition (TPN) in the treatment of critically ill patients has been the subject of debate because it has been associated with…”
Get more information

Parenteral nutrition dysregulates bile salt homeostasis in a rat model of parenteral nutrition-associated liver disease by Koelfat, Kiran V.K, Schaap, Frank G, Hodin, Caroline M.J.M, Visschers, Ruben G.J, Svavarsson, Björn I, Lenicek, Martin, Shiri-Sverdlov, Ronit, Lenaerts, Kaatje, Olde Damink, Steven W.M

“…Summary Background & aims Parenteral nutrition (PN), a lifesaving therapy in patients with intestinal failure, has been associated with hepatobiliary…”
Get full text

Localization of the lipopolysaccharide recognition complex in the human healthy and inflamed premature and adult gut by Wolfs, Tim G.A.M., Derikx, Joep P.M., Hodin, Caroline M.I.M., Vanderlocht, Joris, Driessen, Ann, de Bruïne, Adriaan P., Bevins, Charles L., Lasitschka, Felix, Gassler, Nikolaus, van Gemert, Wim G., Buurman, Wim A.

“…Background: Microbiota in the intestinal lumen provide an abundant source of potentially detrimental antigens, including lipopolysaccharide (LPS), a potent…”
Get full text

Reduced Paneth Cell Antimicrobial Protein Levels Correlate With Activation of the Unfolded Protein Response in the Gut of Obese Individuals by Hodin, Caroline M, Verdam, Froukje J, Grootjans, Joep, Rensen, Sander S, Dejong, Cornelis H, Buurman, Wim A, Greve, Jan Willem, Lenaerts, Kaatje

Get full text

Increased release of sMD-2 during human endotoxemia and sepsis: A role for endothelial cells by Wolfs, Tim G.A.M., Dunn-Siegrist, Irène, van’t Veer, Cornelis, Hodin, Caroline M.I.M., Germeraad, Wilfred T.V., van Zoelen, Marieke A.D., van Suylen, Robert-Jan, Peutz-Kootstra, Carine J., Elson, Greg, Pugin, Jérôme, Buurman, Wim A.

“…MD-2 is the crucial cofactor of TLR4 in the detection of LPS. Here, we show that soluble MD-2 (sMD-2) circulates in plasma of healthy individuals as a…”
Get full text

Decreased expression of Paneth cell antimicrobial peptides coincide with bacterial translocation after starvation by Hodin, Caroline M, Lenaerts, Kaatje, Haan, Jacco‐Juri, Grootjans, Joep, Hadfoune, M'hamed, Hooper, Lora V, Heineman, Eric, Buurman, Wim A

“…The lack of enteral feeding, with or without parenteral nutritional support has been reported to result in increased translocation of bacteria, which is…”
Get full text

FXR agonism protects against liver injury in a rat model of intestinal failure-associated liver disease by Koelfat, Kiran V K, Visschers, Ruben G J, Hodin, Caroline M J M, de Waart, D Rudi, van Gemert, Wim G, Cleutjens, Jack P M, Gijbels, Marion J, Shiri-Sverdlov, Ronit, Mookerjee, Rajeshwar P, Lenaerts, Kaatje, Schaap, Frank G, Steven W M, Olde Damink

“…Intestinal failure-associated liver disease (IFALD) is a clinical challenge. The pathophysiol-ogy is multifactorial and remains poorly understood. Disturbed…”
Get full text

FXR agonism protects against liver injury in a rat model of intestinal failure-associated liver disease by Olde Damink, Steven

Get full text