Search Results - "Hodgson, J"

A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen by Coppé, Jean-Philippe, Patil, Christopher K, Rodier, Francis, Krtolica, Ana, Beauséjour, Christian M, Parrinello, Simona, Hodgson, J Graeme, Chin, Koei, Desprez, Pierre-Yves, Campisi, Judith

“…Cellular senescence irreversibly arrests cell proliferation in response to oncogenic stimuli. Human cells develop a senescence-associated secretory phenotype…”
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Early Warnings of Regime Shifts: A Whole-Ecosystem Experiment by Carpenter, S. R., Cole, J. J., Pace, M. L., Batt, R., Brock, W. A., Cline, T., Coloso, J., Hodgson, J. R., Kitchell, J. F., Seekell, D. A., Smith, L., Weidel, B.

“…Catastrophic ecological regime shifts may be announced in advance by statistical early warning signals such as slowing return rates from perturbation and…”
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Drosophila as a model for homeostatic, antibacterial, and antiviral mechanisms in the gut by Liu, Xi, Hodgson, Jeffrey J, Buchon, Nicolas

“…About the Authors: Xi Liu Affiliation: Cornell Institute for Host Microbe Interactions and Disease, Department of Entomology, Cornell University, Ithaca, New…”
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A brief introduction to mixed effects modelling and multi-model inference in ecology by Harrison, Xavier A, Donaldson, Lynda, Correa-Cano, Maria Eugenia, Evans, Julian, Fisher, David N, Goodwin, Cecily E D, Robinson, Beth S, Hodgson, David J, Inger, Richard

“…The use of linear mixed effects models (LMMs) is increasingly common in the analysis of biological data. Whilst LMMs offer a flexible approach to modelling a…”
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Multiple dimensions underlying the functional organization of the language network by Hodgson, Victoria J., Lambon Ralph, Matthew A., Jackson, Rebecca L.

“…Understanding the different neural networks that support human language is an ongoing challenge for cognitive neuroscience. Which divisions are capable of…”
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Increased microglia/macrophage gene expression in a subset of adult and pediatric astrocytomas by Engler, Jane R, Robinson, Aaron E, Smirnov, Ivan, Hodgson, J Graeme, Berger, Mitchel S, Gupta, Nalin, James, C David, Molinaro, Annette, Phillips, Joanna J

“…Glioblastoma (GBM) is a highly malignant brain tumor with a dismal prognosis. Gene expression profiling of GBM has revealed clinically relevant tumor subtypes,…”
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Fast–slow continuum and reproductive strategies structure plant life-history variation worldwide by Salguero-Gómez, Roberto, Jones, Owen R., Jongejans, Eelke, Blomberg, Simon P., Hodgson, David J., Mbeau-Ache, Cyril, Zuidema, Pieter A., de Kroon, Hans, Buckleya, Yvonne M.

“…The identification of patterns in life-history strategies across the tree of life is essential to our prediction of population persistence, extinction, and…”
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Chaplaincy, Spiritual Care and Moral Injury: Considerations Regarding Screening and Treatment by Carey, Lindsay B, Hodgson, Timothy J

“…Moral injury is a complex trauma related syndrome involving a correlation of biological, psychological, social, and spiritual symptoms that can have…”
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Constraint-Based Approach to Granular Dispersion Rheology by Guy, B M, Richards, J A, Hodgson, D J M, Blanco, E, Poon, W C K

“…We present a phenomenological model for granular suspension rheology in which particle interactions enter as constraints to relative particle motion. By…”
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Induction of Tumors in Mice by Genomic Hypomethylation by Gaudet, François, Hodgson, J. Graeme, Eden, Amir, Jackson-Grusby, Laurie, Dausman, Jessica, Gray, Joe W., Leonhardt, Heinrich, Jaenisch, Rudolf

“…Genome-wide DNA hypomethylation occurs in many human cancers, but whether this epigenetic change is a cause or consequence of tumorigenesis has been unclear…”
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Discovery and Characterization of SY-1365, a Selective, Covalent Inhibitor of CDK7 by Hu, Shanhu, Marineau, Jason J, Rajagopal, Nisha, Hamman, Kristin B, Choi, Yoon Jong, Schmidt, Darby R, Ke, Nan, Johannessen, Liv, Bradley, Michael J, Orlando, David A, Alnemy, Sydney R, Ren, Yixuan, Ciblat, Stephane, Winter, Dana K, Kabro, Anzhelika, Sprott, Kevin T, Hodgson, J Graeme, Fritz, Christian C, Carulli, John P, di Tomaso, Emmanuelle, Olson, Eric R

“…Recent studies suggest that targeting transcriptional machinery can lead to potent and selective anticancer effects in cancers dependent on high and constant…”
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Assessment of the higher order structure of Humira®, Remicade®, Avastin®, Rituxan®, Herceptin®, and Enbrel® by 2D-NMR fingerprinting by Hodgson, Derek J., Ghasriani, Houman, Aubin, Yves

“…•A simple method to prepare Fab and Fc fragments from monoclonal antibodies samples.•Demonstration of feasibility to collect 2D-NMR spectra of mAb products…”
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miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells by Silber, Joachim, Lim, Daniel A, Petritsch, Claudia, Persson, Anders I, Maunakea, Alika K, Yu, Mamie, Vandenberg, Scott R, Ginzinger, David G, James, C David, Costello, Joseph F, Bergers, Gabriele, Weiss, William A, Alvarez-Buylla, Arturo, Hodgson, J Graeme

“…Glioblastoma multiforme (GBM) is an invariably fatal central nervous system tumor despite treatment with surgery, radiation, and chemotherapy. Further insights…”
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Perils and pitfalls of mixed-effects regression models in biology by Silk, Matthew J., Harrison, Xavier A., Hodgson, David J.

“…Biological systems, at all scales of organisation from nucleic acids to ecosystems, are inherently complex and variable. Biologists therefore use statistical…”
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Why do sperm carry RNA? Relatedness, conflict, and control by Hosken, David J., Hodgson, David J.

“…•Sperm carry a large RNA payload.•We suggest novel functions for some of these RNAs.•We also propose how to test these putative functions. Classically, sperm…”
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international terminology for grazing lands and grazing animals by Allen, V.G., Batello, C., Berretta, E.J., Hodgson, J., Kothmann, M., Li, X., McIvor, J., Milne, J., Morris, C., Peeters, A., Sanderson, M.

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Infected or informed? Social structure and the simultaneous transmission of information and infectious disease by Evans, Julian C., Silk, Matthew J., Boogert, Neeltje J., Hodgson, David J.

“…Social interactions present opportunities for both information and infection to spread through populations. Social learning is often proposed as a key benefit…”
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Using Social Network Measures in Wildlife Disease Ecology, Epidemiology, and Management by SILK, MATTHEW J., CROFT, DARREN P., DELAHAY, RICHARD J., HODGSON, DAVID J., BOOTS, MIKE, WEBER, NICOLA, McDONALD, ROBBIE A.

“…Contact networks, behavioral interactions, and shared use of space can all have important implications for the spread of disease in animals. Social networks…”
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Soft matter science and the COVID-19 pandemic by Poon, Wilson C K, Brown, Aidan T, Direito, Susana O L, Hodgson, Daniel J M, Le Nagard, Lucas, Lips, Alex, MacPhee, Cait E, Marenduzzo, Davide, Royer, John R, Silva, Andreia F, Thijssen, Job H J, Titmuss, Simon

“…Much of the science underpinning the global response to the COVID-19 pandemic lies in the soft matter domain. Coronaviruses are composite particles with a core…”
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How Interatomic Steps in the Exact Kohn–Sham Potential Relate to Derivative Discontinuities of the Energy by Hodgson, M. J. P, Kraisler, Eli, Schild, Axel, Gross, E. K. U

“…Accurate density functional calculations hinge on reliable approximations to the unknown exchange-correlation (xc) potential. The most popular approximations…”
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