Search Results - "Hodgson, David R. W"

Allophycocyanin A is a carbon dioxide receptor in the cyanobacterial phycobilisome by Guillén-García, Alejandra, Gibson, Savannah E. R., Jordan, Caleb J. C., Ramaswamy, Venkata K., Linthwaite, Victoria L., Bromley, Elizabeth H. C., Brown, Adrian P., Hodgson, David R. W., Blower, Tim R., Verlet, Jan R. R., Degiacomi, Matteo T., Pålsson, Lars-Olof, Cann, Martin J.

“…Light harvesting is fundamental for production of ATP and reducing equivalents for CO 2 fixation during photosynthesis. However, electronic energy transfer…”
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The synthesis of peptides and proteins containing non-natural amino acids by Hodgson, David R W, Sanderson, John M

“…Methods for the incorporation of non-natural amino acids into proteins have advanced significantly over recent years and in this tutorial review we aim to give…”
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A quantitative reactivity scale for electrophilic fluorinating reagents by Rozatian, Neshat, Ashworth, Ian W, Sandford, Graham, Hodgson, David R W

“…Electrophilic N-F fluorination agents underpin the introduction of fluorine in aliphatic systems across drug and academic research. The choice of N-F reagent…”
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The preparation of graft copolymers of cellulose and cellulose derivatives using ATRP under homogeneous reaction conditions by Joubert, Fanny, Musa, Osama M, Hodgson, David R W, Cameron, Neil R

“…In this comprehensive review, we report on the preparation of graft-copolymers of cellulose and cellulose derivatives using atom transfer radical…”
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Stereoselective Syntheses of 3′-Hydroxyamino- and 3′-Methoxyamino-2′,3′-Dideoxynucleosides by Bose, Sritama, Hodgson, David R. W

“…Aminonucleosides are used as key motifs in medicinal and bioconjugate chemistry; however, existing strategies toward 3′-hypernucleophilic amine systems do not…”
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Nucleophilic displacement reactions of 5'-derivatised nucleosides in a vibration ball mill by Eguaogie, Olga, Conlon, Patrick F, Ravalico, Francesco, Sweet, Jamie S T, Elder, Thomas B, Conway, Louis P, Lennon, Marc E, Hodgson, David R W, Vyle, Joseph S

“…Vibration ball-milling in a zirconia-lined vessel afforded clean and quantitative nucleophilic displacement reactions between 4-methoxybenzylthiolate salts and…”
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Regulation of prokaryotic adenylyl cyclases by CO2 by Hammer, Arne, Hodgson, David R W, Cann, Martin J

“…The Slr1991 adenylyl cyclase of the model prokaroyte Synechocystis PCC 6803 was stimulated 2-fold at 20 mM total C(i) (inorganic carbon) at pH 7.5 through an…”
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Preparation of an Antibacterial Poly(ionic liquid) Graft Copolymer of Hydroxyethyl Cellulose by Joubert, Fanny, Yeo, R. Paul, Sharples, Gary J, Musa, Osama M, Hodgson, David R. W, Cameron, Neil R

“…Poly­(ionic liquid)­s (P­(IL)­s) of different degrees of polymerization (10, 50, and 100) were prepared via RAFT polymerization using an alkyne-terminated…”
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The identification of carbon dioxide mediated protein post-translational modifications by Linthwaite, Victoria L., Janus, Joanna M., Brown, Adrian P., Wong-Pascua, David, O’Donoghue, AnnMarie C., Porter, Andrew, Treumann, Achim, Hodgson, David R. W., Cann, Martin J.

“…Carbon dioxide is vital to the chemistry of life processes including metabolism, cellular homoeostasis, and pathogenesis. CO 2 is generally unreactive but can…”
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Stimulation of Mammalian G-protein-responsive Adenylyl Cyclases by Carbon Dioxide by Townsend, Philip D., Holliday, Phillip M., Fenyk, Stepan, Hess, Kenneth C., Gray, Michael A., Hodgson, David R.W., Cann, Martin J.

“…Carbon dioxide is fundamental to the physiology of all organisms. There is considerable interest in the precise molecular mechanisms that organisms use to…”
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Synthesis of 2,2-difluoro-1,3-diketone and 2,2-difluoro-1,3-ketoester derivatives using fluorine gas by Hampton, Alexander S, Hodgson, David R W, McDougald, Graham, Wang, Linhua, Sandford, Graham

“…Solutions of 1,3-diketones and 1,3-ketoester derivatives react with fluorine to give the corresponding 2,2-difluoro-1,3-dicarbonyl derivatives in the presence…”
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Phosphate analogues in the dissection of mechanism by Korhonen, Heidi J, Conway, Louis P, Hodgson, David RW

“…•Analogues of phosphate monoesters and diesters, and phosphoanhydrides are reviewed.•Hydrolysable analogues provide details of the mechanisms of…”
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Author Correction: The identification of carbon dioxide mediated protein post-translational modifications by Linthwaite, Victoria L., Janus, Joanna M., Brown, Adrian P., Wong-Pascua, David, O’Donoghue, AnnMarie C., Porter, Andrew, Treumann, Achim, Hodgson, David R. W., Cann, Martin J.

“…The original version of this Article omitted the following from the Acknowledgements: ‘This work was support by EPSRC grant EP/K504336/1 and Leverhulme Trust…”
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The Role of Protein-Ligand Contacts in Allosteric Regulation of the Escherichia coli Catabolite Activator Protein by Townsend, Philip D., Rodgers, Thomas L., Glover, Laura C., Korhonen, Heidi J., Richards, Shane A., Colwell, Lucy J., Pohl, Ehmke, Wilson, Mark R., Hodgson, David R.W., McLeish, Tom C.B., Cann, Martin J.

“…Allostery is a fundamental process by which ligand binding to a protein alters its activity at a distant site. Both experimental and theoretical evidence…”
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Chemical approaches towards unravelling kinase-mediated signalling pathways by Hodgson, David R W, Schröder, Martin

“…Protein kinases control the function of about one third of cellular proteins by catalysing the transfer of the γ-phosphate group of ATP onto their substrate…”
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Hydrolysis Studies of Phosphodichloridate and Thiophosphodichloridate Ions by Delley, Richard J, O’Donoghue, AnnMarie C, Hodgson, David R. W

“…We report the pH-k obs profiles for the hydrolyses of phosphodichloridate and thiophosphodichloridate ions in aqueous solutions. Both species show broad pH–k…”
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The synthesis, conformation and hydrolytic stability of an N,S-bridging thiophosphoramidate analogue of thymidylyl-3',5'-thymidine by Conway, Louis P, Mikkola, Satu, O'Donoghue, AnnMarie C, Hodgson, David R W

“…A 3'-N,5'-S-bridging thiophosphoramidate analogue of thymidylyl-3',5'-thymidine was synthesised under aqueous conditions. (1)H NMR conformational measurements…”
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A procedure for the preparation and isolation of nucleoside-5'-diphosphates by Korhonen, Heidi J, Bolt, Hannah L, Hodgson, David R W

“…Tris[bis(triphenylphosphoranylidene)ammonium] pyrophosphate (PPN pyrophosphate) was used in the SN2 displacements of the tosylate ion from 5'-tosylnucleosides…”
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Synthesis of thiophosphoramidates in water: click chemistry for phosphates by Trmčić, Milena, Hodgson, David R W

“…An aqueous method for the preparation of N,S-dialkyl thiophosphoramidates is reported. Thiophosphorylation of alkylamines was performed using SPCl(3) in…”
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Synthesis of 5'-amino-5'-deoxyguanosine-5'-N-phosphoramidate and its enzymatic incorporation at the 5'-termini of RNA molecules by Williamson, David, Cann, Martin J, Hodgson, David R W

“…5'-amino-5'-deoxyguanosine-5'-N-phosphoramidate (GNHP) was synthesized in four steps from guanosine and was found to initiate T7 RNAP-promoted transcriptions…”
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