Search Results - "Hodgkinson, C."

Olive (Olea europaea L.) leaf polyphenols improve insulin sensitivity in middle-aged overweight men: a randomized, placebo-controlled, crossover trial by de Bock, Martin, Derraik, José G B, Brennan, Christine M, Biggs, Janene B, Morgan, Philip E, Hodgkinson, Steven C, Hofman, Paul L, Cutfield, Wayne S

“…Olive plant leaves (Olea europaea L.) have been used for centuries in folk medicine to treat diabetes, but there are very limited data examining the effects of…”
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Interaction between a functional MAOA locus and childhood sexual abuse predicts alcoholism and antisocial personality disorder in adult women by Ducci, F, Enoch, M-A, Hodgkinson, C, Xu, K, Catena, M, Robin, R W, Goldman, D

“…Women who have experienced childhood sexual abuse (CSA) have an increased risk of alcoholism and antisocial personality disorder (ASPD). Among male subjects, a…”
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Methylomic profiling and replication implicates deregulation of PCSK9 in alcohol use disorder by Lohoff, F W, Sorcher, J L, Rosen, A D, Mauro, K L, Fanelli, R R, Momenan, R, Hodgkinson, C A, Vendruscolo, L F, Koob, G F, Schwandt, M, George, D T, Jones, I S, Holmes, A, Zhou, Z, Xu, M-J, Gao, B, Sun, H, Phillips, M J, Muench, C, Kaminsky, Z A

“…Alcohol use disorder (AUD) is a common and chronic disorder with substantial effects on personal and public health. The underlying pathophysiology is poorly…”
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Tumourigenic non-small-cell lung cancer mesenchymal circulating tumour cells: a clinical case study by Morrow, C.J., Trapani, F., Metcalf, R.L., Bertolini, G., Hodgkinson, C.L., Khandelwal, G., Kelly, P., Galvin, M., Carter, L., Simpson, K.L., Williamson, S., Wirth, C., Simms, N., Frankliln, L., Frese, K.K., Rothwell, D.G., Nonaka, D., Miller, C.J., Brady, G., Blackhall, F.H., Dive, C.

“…Over the past decade, numerous reports describe the generation and increasing utility of non-small-cell lung cancer (NSCLC) patient-derived xenografts (PDX)…”
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FAAH selectively influences placebo effects by Peciña, M, Martínez-Jauand, M, Hodgkinson, C, Stohler, C S, Goldman, D, Zubieta, J K

“…Endogenous opioid and cannabinoid systems are thought to act synergistically regulating antinociceptive and reward mechanisms. To further understand the human…”
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Functional genetic variants that increase synaptic serotonin and 5-HT3 receptor sensitivity predict alcohol and drug dependence by Enoch, M-A, Gorodetsky, E, Hodgkinson, C, Roy, A, Goldman, D

“…The 5-HT3 receptor is rapidly potentiated by ethanol and mediates fast excitatory serotonin (5-HT) transmission that modulates dopamine release in the reward…”
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The contribution of rare and common variants in 30 genes to risk nicotine dependence by Yang, J, Wang, S, Yang, Z, Hodgkinson, C A, Iarikova, P, Ma, J Z, Payne, T J, Goldman, D, Li, M D

“…Genetic and functional studies have revealed that both common and rare variants of several nicotinic acetylcholine receptor subunits are associated with…”
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The glucagon-like peptide-1 receptor as a potential treatment target in alcohol use disorder: evidence from human genetic association studies and a mouse model of alcohol dependence by Suchankova, P, Yan, J, Schwandt, M L, Stangl, B L, Caparelli, E C, Momenan, R, Jerlhag, E, Engel, J A, Hodgkinson, C A, Egli, M, Lopez, M F, Becker, H C, Goldman, D, Heilig, M, Ramchandani, V A, Leggio, L

“…The hormone glucagon-like peptide-1 (GLP-1) regulates appetite and food intake. GLP-1 receptor (GLP-1R) activation also attenuates the reinforcing properties…”
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A CHRNA5 allele related to nicotine addiction and schizophrenia by Hong, L. E., Yang, X., Wonodi, I., Hodgkinson, C. A., Goldman, D., Stine, O. C., Stein, E. S., Thaker, G. K.

“…Schizophrenia and nicotine addiction are both highly heritable phenotypes. Because individuals with schizophrenia have a higher rate of smoking than those in…”
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Association of genetic ancestry with striatal dopamine D2/D3 receptor availability by Wiers, C E, Towb, P C, Hodgkinson, C A, Shen, P-H, Freeman, C, Miller, G, Lindgren, E, Shokri-Kojori, E, Demiral, Ş B, Kim, S W, Tomasi, D, Sun, H, Wang, G-J, Goldman, D, Volkow, N D

“…Despite ethnic differences in allele frequencies of variants in dopaminergic genes associated with dopamine D2/D3 receptor availability (D2R), no study to date…”
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A variant on the kappa opioid receptor gene (OPRK1) is associated with stress response and related drug craving, limbic brain activation and cocaine relapse risk by Xu, K, Seo, D, Hodgkinson, C, Hu, Y, Goldman, D, Sinha, R

“…Stress increases drug craving and relapse risk. The kappa opioid receptor gene ( OPRK1 ) mediates stress responses. Here, we examined whether the OPRK1…”
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Defining the role of corticotropin releasing factor binding protein in alcohol consumption by Haass-Koffler, C L, Henry, A T, Melkus, G, Simms, J A, Naemmuddin, M, Nielsen, C K, Lasek, A W, Magill, M, Schwandt, M L, Momenan, R, Hodgkinson, C A, Bartlett, S E, Swift, R M, Bonci, A, Leggio, L

“…The corticotropin releasing factor (CRF) exerts its effects by acting on its receptors and on the binding protein (CRFBP), and has been implicated in alcohol…”
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DISC-1 Leu607Phe alleles differentially affect centrosomal PCM1 localization and neurotransmitter release by Eastwood, S L, Hodgkinson, C A, Harrison, P J

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Prefrontal cortex lesions and MAO-A modulate aggression in penetrating traumatic brain injury by PARDINI, M, KRUEGER, F, HODGKINSON, C, RAYMONT, V, FERRIER, C, GOLDMAN, D, STRENZIOK, M, GUIDA, S, GRAFMAN, J

“…This study investigates the interaction between brain lesion location and monoamine oxidase A (MAO-A) in the genesis of aggression in patients with penetrating…”
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OPRM1 gene variants modulate amphetamine‐induced euphoria in humans by Dlugos, A. M., Hamidovic, A., Hodgkinson, C., Shen, P. H., Goldman, D., Palmer, A. A., de Wit, H.

“…The μ‐opioid receptor is involved in the rewarding effects of not only opioids like morphine but also psychostimulants like amphetamine. This study aimed to…”
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Biomarkers of chemotherapy resistance in breast cancer identified by proteomics: Current status by Hodgkinson, Victoria C, Eagle, Gina L, Drew, Philip J, Lind, Michael J, Cawkwell, Lynn

“…Abstract This review describes and discusses the advantages and limitations of proteomic approaches in the identification of biomarkers associated with…”
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437 PIM kinase inhibitor AZD1208 sensitises SCLC to BH3 mimetic AZD4320 by Sloane, R, Bola, B, Lancashire, M, Hodgkinson, C, Morrow, C, Simpson, K, Dive, C

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A preliminary study suggests that nicotine and prefrontal dopamine affect cortico‐striatal areas in smokers with performance feedback by Lee, M. R., Gallen, C. L., Ross, T. J., Kurup, P., Salmeron, B. J., Hodgkinson, C. A., Goldman, D., Stein, E. A., Enoch, M. A.

“…Nicotine and tonic dopamine (DA) levels [as inferred by catechol‐O‐methyl tranferase (COMT) Val158Met genotype] interact to affect prefrontal processing…”
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Sprouting success of shrubs after fire: height-dependent relationships for different strategies by Hodgkinson, K.C

“…The sprouting success of co-occurring populations of shrub species in a temperate woodland of semi-arid Australia was investigated and related to population…”
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A caspase-3 ‘death-switch’ in colorectal cancer cells for induced and synchronous tumor apoptosis in vitro and in vivo facilitates the development of minimally invasive cell death biomarkers by Simpson, K L, Cawthorne, C, Zhou, C, Hodgkinson, C L, Walker, M J, Trapani, F, Kadirvel, M, Brown, G, Dawson, M J, MacFarlane, M, Williams, K J, Whetton, A D, Dive, C

“…Novel anticancer drugs targeting key apoptosis regulators have been developed and are undergoing clinical trials. Pharmacodynamic biomarkers to define the…”
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