Search Results - "Hodgins, M. B."

Expression of the sarco/endoplasmic reticulum calcium ATPase type 2 and 3 isoforms in normal skin and Darier's disease by Tavadia, S., Authi, K.S., Hodgins, M.B., Munro, C.S.

“…Summary Background  Darier's disease (DD) is caused by mutations in ATP2A2, which encodes the sarco/endoplasmic reticulum calcium ATPase type 2 (SERCA2), a…”
Get full text

Pachyonychia congenita type 2: abnormal dentition extending into adulthood by Zamiri, M., McLean, W.H.I., Hodgins, M.B., Munro, C.S.

Get full text

Localization of androgen receptors in human skin by immunohistochemistry: implications for the hormonal regulation of hair growth, sebaceous glands and sweat glands by Choudhry, R, Hodgins, M B, Van der Kwast, T H, Brinkmann, A O, Boersma, W J

“…A mouse monoclonal antibody against the N-terminal region of human androgen receptor (AR) was used to identify receptors by immunoperoxidase staining in frozen…”
Get more information

Upregulation of Connexin 26 is a Feature of Keratinocyte Differentiation in Hyperproliferative Epidermis, Vaginal Epithelium, and Buccal Epithelium by Lucke, Tom, Choudhry, Rukhsana, Thom, Russell, Selmer, Inger-Sofie, Burden, A. David, Hodgins, Malcolm B.

“…In epidermis, it has been suggested, intercellular communication through gap junctions is important in coordinating cell behavior. The connexins, may…”
Get full text

An immunohistochemical study of androgen, oestrogen and progesterone receptors in the vulva and vagina by Hodgins, Malcolm B., Spike, Rosemary C., Mackie, Rona M., MacLean, Allan B.

“…Objective Tomap potential sites of sex steroid action in the human vulva. Methods Monoclonal antibodies to androgen, oestrogen and progesterone receptors were…”
Get full text

Polyamines regulate gap junction communication in connexin 43-expressing cells by Shore, L, McLean, P, Gilmour, S K, Hodgins, M B, Finbow, M E

“…The control of cell-cell communication through gap junctions is thought to be crucial in normal tissue function and during various stages of tumorigenesis…”
Get full text

Changing patterns of gap junctional intercellular communication and connexin distribution in mouse epidermis and hair follicles during embryonic development by Choudhry, R., Pitts, J.D., Hodgins, M.B.

“…In the mouse embryo between embryonic days 12 (E12) and 16, regular arrays of epidermal placodes on the mystacial pad develop into whisker follicles. This…”
Get full text

Correlation of clinical, endocrine and molecular abnormalities with in vivo responses to high-dose testosterone in patients with partial androgen insensitivity syndrome by Tincello, D. G., Saunders, P. T. K., Hodgins, M. B., Simpson, N. B., Edwards, C. R. W., Hargreaves, T. B., Wu, F. C. W.

“…OBJECTIVE To investigate the responses of two patients previously diagnosed as Reifenstein's syndrome to graded high‐dose testosterone in terms of hormone…”
Get full text

Aberrant Splicing of Androgen Receptor mRNA Results in Synthesis of a Nonfunctional Receptor Protein in a Patient with Androgen Insensitivity by Ris-Stalpers, C., G. G. J. M. Kuiper, Faber, P. W., Schweikert, H. U., van Rooij, H. C. J., Zegers, N. D., Hodgins, M. B., Degenhart, H. J., Trapman, J., Brinkmann, A. O.

“…Androgen insensitivity is a disorder in which the correct androgen response in an androgen target cell is impaired. The clinical symptoms of this X…”
Get full text

Characterization and Chromosomal Localization of Human Hair-Specific Keratin Genes and Comparative Expression During the Hair Growth Cycle by Bowden, Paul E., Hainey, Sandra D., Parker, Gillian, Jones, David O., Zimonjic, Drazen, Popescu, Nicholas, Hodgins, Malcolm B.

“…During anagen, cell proliferation in the germinative matrix of the hair follicle gives rise to the fiber and inner root sheath. The hair fiber is constructed…”
Get full text

Mutation in DSG1 causing autosomal dominant striate palmoplantar keratoderma by Zamiri, M., Smith, F.J.D., Campbell, L.E., Tetley, L., Eady, R.A.J., Hodgins, M.B., McLean, W.H.I., Munro, C.S.

Get full text

Human diseases: clues to cracking the connexin code? by Kelsell, David P., Dunlop, John, Hodgins, Malcolm B.

“…The vertebrate gap junctions formed by the connexin family of transmembrane proteins came to the attention of geneticists in 1993 with the identification of…”
Get full text

An in vitro model of dermatophyte invasion of the human hair follicle by RASHID, A, HODGINS, M. B, RICHARDSON, M. D

“…A novel in vitro model for the study of hair invasion by Trichophyton mentagrophytes was developed. Hair was obtained by microdissection and plucking…”
Get full text

trans-dominant inhibition of connexin-43 by mutant connexin-26: implications for dominant connexin disorders affecting epidermal differentiation by Rouan, F, White, T W, Brown, N, Taylor, A M, Lucke, T W, Paul, D L, Munro, C S, Uitto, J, Hodgins, M B, Richard, G

“…Dominant mutations of GJB2-encoding connexin-26 (Cx26) have pleiotropic effects, causing either hearing impairment (HI) alone or in association with…”
Get full text

Immunohistochemical localization of estrogen receptors in the vulva and vagina by MACLEAN, A. B, NICOL, L. A, HODGINS, M. B

“…A rat monoclonal antibody against human estrogen receptor (ER) was used to localize nuclear ER in frozen tissue sections with the peroxidase-antiperoxidase…”
Get full text

The relationship between connexins, gap junctions, tissue architecture and tumour invasion, as studied in a novel in vitro model of HPV-16-associated cervical cancer progression by AASEN, Trond, HODGINS, Malcolm B, EDWARD, Michael, GRAHAM, Sheila V

“…Disruption of gap junctional intercellular communication (GJIC) and/or connexins (gap junction proteins) is frequently reported in malignant cell lines and…”
Get full text

Peripheral oestrogen synthesis in man: its regulation and possible physiological significance by Hodgins, M B

Get more information

Androgens and sweating by Kunkeler, L, Hodgins, M B

Get more information

Binding of androgens in 5 alpha-reductase-deficient human genital skin fibroblasts: inhibition by progesterone and its metabolites by Hodgins, M B

“…Binding of [3H]testosterone and 5alpha-dihydro[3H]testosterone ([3H]DHT) to specific androgen-receptor sites of 5alpha-reductase-deficient human genital skin…”
Get more information

The effect of treatment with 13-cis-retinoic acid on the metabolic burst of peripheral blood neutrophils from patients with acne by Perkins, W, Crocket, K V, Hodgins, M B, Mackie, R M, Lackie, J M

“…The N-formylmethionyl-leucyl-phenylalanine (f-MLP)-induced metabolic burst activity of peripheral blood neutrophils isolated from acne patients undergoing…”
Get more information