Search Results - "Hodgins, Douglas C"

Characterization of Innate Responses Induced by PLGA Encapsulated- and Soluble TLR Ligands In Vitro and In Vivo in Chickens by Alkie, Tamiru N, Taha-Abdelaziz, Khaled, Barjesteh, Neda, Bavananthasivam, Jegarubee, Hodgins, Douglas C, Sharif, Shayan

“…Natural or synthetic Toll-like receptor (TLR) ligands trigger innate responses by interacting with distinct TLRs. TLR ligands can thus serve as vaccine…”
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Gene expression profiling of chicken cecal tonsils and ileum following oral exposure to soluble and PLGA-encapsulated CpG ODN, and lysate of Campylobacter jejuni by Taha-Abdelaziz, Khaled, Alkie, Tamiru Negash, Hodgins, Douglas C., Yitbarek, Alexander, Shojadoost, Bahram, Sharif, Shayan

“…•Soluble and PLGA-encapsulated-CpG ODN, and C. jejuni lysate elicit cytokine expression in the intestinal tissue.•Incorporation of CpG ODN into PLGA NPs…”
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Characterization of host responses induced by Toll-like receptor ligands in chicken cecal tonsil cells by Taha-abdelaziz, Khaled, Alkie, Tamiru Negash, Hodgins, Douglas C., Shojadoost, Bahram, Sharif, Shayan

“…•TLR ligands elicit innate responses in cecal tonsil mononuclear cells.•CpG ODN elicits higher responses in comparison to LPS or Pam3CSK4.•The use of TLR…”
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Investigating the IgM and IgG B Cell Receptor Repertoires and Expression of Ultralong Complementarity Determining Region 3 in Colostrum and Blood from Holstein-Friesian Cows at Calving by Altvater-Hughes, Tess E, Hodgins, Harold P, Hodgins, Douglas C, Bauman, Cathy A, Paibomesai, Marlene A, Mallard, Bonnie A

“…In cattle, colostral maternal immunoglobulins and lymphocytes transfer across the neonate's intestinal epithelium to provide protection against pathogens. This…”
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Advances in Poultry Vaccines: Leveraging Biotechnology for Improving Vaccine Development, Stability, and Delivery by Abdelaziz, Khaled, Helmy, Yosra A, Yitbarek, Alexander, Hodgins, Douglas C, Sharafeldin, Tamer A, Selim, Mohamed S H

“…With the rapidly increasing demand for poultry products and the current challenges facing the poultry industry, the application of biotechnology to enhance…”
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Transmission of H9N2 Low Pathogenicity Avian Influenza Virus (LPAIV) in a Challenge-Transmission Model by Raj, Sugandha, Astill, Jake, Alqazlan, Nadiyah, Boodhoo, Nitish, Hodgins, Douglas C, Nagy, Éva, Mubareka, Samira, Karimi, Khalil, Sharif, Shayan

“…Migratory birds are major reservoirs for avian influenza viruses (AIV), which can be transmitted to poultry and mammals. The H9N2 subtype of AIV has become…”
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Evaluation of a polysaccharide conjugate vaccine to reduce colonization by Campylobacter jejuni in broiler chickens by Hodgins, Douglas C, Barjesteh, Neda, St Paul, Michael, Ma, Zuchao, Monteiro, Mario A, Sharif, Shayan

“…Campylobacter jejuni is a leading bacterial cause of food-borne illness in humans. Symptoms range from mild gastroenteritis to dysentery. Contaminated chicken…”
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Local Innate Responses to TLR Ligands in the Chicken Trachea by Barjesteh, Neda, Alkie, Tamiru Negash, Hodgins, Douglas C, Nagy, Éva, Sharif, Shayan

“…The chicken upper respiratory tract is the portal of entry for respiratory pathogens, such as avian influenza virus (AIV). The presence of microorganisms is…”
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Commensal gut microbiota can modulate adaptive immune responses in chickens vaccinated with whole inactivated avian influenza virus subtype H9N2 by Yitbarek, Alexander, Astill, Jake, Hodgins, Douglas C., Parkinson, John, Nagy, Éva, Sharif, Shayan

“…Variations in the composition of commensal gut microbiota have been reported to be major contributors to differences in responses to vaccination among…”
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Effects of early feeding and dietary interventions on development of lymphoid organs and immune competence in neonatal chickens: A review by Taha-Abdelaziz, Khaled, Hodgins, Douglas C., Lammers, Aart, Alkie, Tamiru Negash, Sharif, Shayan

“…With the ongoing intensification of the poultry industry and the continuous need to control pathogens, there is a critical need to extend our understanding of…”
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Functional mapping of the porcine reproductive and respiratory syndrome virus capsid protein nuclear localization signal and its pathogenic association by Pei, Yanlong, Hodgins, Douglas C., Lee, Changhee, Calvert, Jay G., Welch, Siao-Kun W., Jolie, Rika, Keith, Marcia, Yoo, Dongwan

“…PRRSV (porcine reproductive and respiratory syndrome virus) nucleocapsid (N) protein is the most abundant structural protein of the virus. During infection,…”
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Gut microbiota-mediated protection against influenza virus subtype H9N2 in chickens is associated with modulation of the innate responses by Yitbarek, Alexander, Taha-Abdelaziz, Khaled, Hodgins, Douglas C., Read, Leah, Nagy, Éva, Weese, J. Scott, Caswell, Jeff L., Parkinson, John, Sharif, Shayan

“…Commensal gut microbiota plays an important role in health and disease. The current study was designed to assess the role of gut microbiota of chickens in the…”
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A Multivalent Mannheimia-Bibersteinia Vaccine Protects Bighorn Sheep against Mannheimia haemolytica Challenge by Subramaniam, Renuka, Shanthalingam, Sudarvili, Bavananthasivam, Jegarubee, Kugadas, Abirami, Potter, Kathleen A, Foreyt, William J, Hodgins, Douglas C, Shewen, Patricia E, Barrington, George M, Knowles, Donald P, Srikumaran, Subramaniam

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Development of innate immunity in chicken embryos and newly hatched chicks: a disease control perspective by Alkie, Tamiru N., Yitbarek, Alexander, Hodgins, Douglas C., Kulkarni, Raveendra R., Taha-Abdelaziz, Khaled, Sharif, Shayan

“…Newly hatched chickens are confronted by a wide array of pathogenic microbes because their adaptive immune defences have limited capabilities to control these…”
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Necrotic enteritis in chickens: a review of pathogenesis, immune responses and prevention, focusing on probiotics and vaccination by Alizadeh, Mohammadali, Shojadoost, Bahram, Boodhoo, Nitish, Astill, Jake, Taha-Abdelaziz, Khaled, Hodgins, Douglas C, Kulkarni, Raveendra R, Sharif, Shayan

“…Necrotic enteritis (NE), caused by Clostridium perfringens (CP), is one of the most common of poultry diseases, causing huge economic losses to the poultry…”
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Oral administration of PLGA-encapsulated CpG ODN and Campylobacter jejuni lysate reduces cecal colonization by Campylobacter jejuni in chickens by Taha-Abdelaziz, Khaled, Hodgins, Douglas C., Alkie, Tamiru Negash, Quinteiro-Filho, Wanderely, Yitbarek, Alexander, Astill, Jake, Sharif, Shayan

“…•Oral administration of CpG ODN significantly reduces Campylobacter colonization.•PLGA NPs formulations enhance the ability of CpG ODN to reduce Campylobacter…”
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The effects of timing of high immune response phenotyping in relation to weaning on immune responses of crossbred beef calves by Beard, Shannon C, Schmied, Julie D, Hodgins, Douglas C, Mallard, Bonnie A

“…Abstract Genetic selection for immune response has the potential to increase the sustainability of the beef industry by breeding cattle that are productive yet…”
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Reduction of avian influenza virus shedding by administration of Toll-like receptor ligands to chickens by Barjesteh, Neda, Shojadoost, Bahram, Brisbin, Jennifer T, Emam, Mehdi, Hodgins, Douglas C, Nagy, Éva, Sharif, Shayan

“…Abstract Avian influenza viruses (AIV) are of concern to the poultry industry. Outbreaks of AIV highlight the urgent need for effective control measures…”
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Vaccination of neonates: Problem and issues by Hodgins, Douglas C, Shewen, Patricia E

“…Highlights ► Corticosteroids, cytokines and maternal antibodies affect neonatal immune responses. ► Non-rodent, non-umbilical cord blood models of neonatal…”
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Concentration and heritability of immunoglobulin G and natural antibody immunoglobulin M in dairy and beef colostrum along with serum total protein in their calves by Altvater-Hughes, Tess E, Hodgins, Douglas C, Wagter-Lesperance, Lauraine, Beard, Shannon C, Cartwright, Shannon L, Mallard, Bonnie A

“…Abstract Immunoglobulin (Ig) G and natural antibody (NAb) IgM are passively transferred to the neonatal calf through bovine colostrum. Maternal IgG provides…”
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