Search Results - "Hodges, Vivien M"

Pathophysiology of anemia and erythrocytosis by Hodges, Vivien M, Rainey, Susan, Lappin, Terence R, Maxwell, A. Peter

“…Abstract An increasing understanding of the process of erythropoiesis raises some interesting questions about the pathophysiology, diagnosis and treatment of…”
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Erythropoietin-induced activation of the JAK2/STAT5, PI3K/Akt, and Ras/ERK pathways promotes malignant cell behavior in a modified breast cancer cell line by Shi, Zhanzhong, Hodges, Vivien M, Dunlop, Elaine A, Percy, Melanie J, Maxwell, Alexander P, El-Tanani, Mohamed, Lappin, Terry R J

“…Erythropoietin (Epo), the major regulator of erythropoiesis, and its cognate receptor (EpoR) are also expressed in nonerythroid tissues, including tumors…”
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GATA2 regulates the erythropoietin receptor in t(12;21) ALL by Gaine, Marie E, Sharpe, Daniel J, Smith, James S, Colyer, Hilary A A, Hodges, Vivien M, Lappin, Terry R, Mills, Ken I

“…The t(12;21) (p13;q22) chromosomal translocation resulting in the fusion gene is the most frequent structural cytogenetic abnormality in children with acute…”
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Erythroblasts from Friend virus infected‐ and phenylhydrazine‐treated mice accurately model erythroid differentiation by Hodges, Vivien M., Winter, Paul C., Lappin, Terence R. J.

“…The dynamics of gene expression during terminal erythroid differentiation have been examined in three murine models; the erythroleukaemia cell line HCD‐57 and…”
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Demonstration of mRNA for five species of cytochrome P450 in human bone marrow, bone marrow‐derived macrophages and human haemopoietic cell lines by Hodges, Vivien M., Molloy, Gael Y., Wickramasinghe

“…The expression of mRNA for five cytochrome P450s (CYP1A1, 2A6/7, 2D6, 2E1 and 3A4) was studied in human bone marrow, bone‐marrow‐derived macrophages and blood…”
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PHF23: A Novel Erythropoietin-Induced Gene Associated with AML and MDS by Hodges, Vivien M., Rainey, Susan, Smyth, Victoria, Mills, Ken, Lappin, Terence R.J., Maxwell, A. Peter

“…Chromosomal translocations in a number of hematopoietic malignancies, including AML and MDS, result in the formation of NUP98 gene chimeras. Recently, fusion…”
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Analysis of HOXA5 and HOXB3 Expression Complements Conventional Cytogenetic Analysis in Acute Myeloid Leukemia by Finnegan, Damian P.J., Hodges, Vivien M., Thompson, Alexander, Quinn, Michael F., Humphries, Mervyn, Lappin, Terence R.J., McMullin, Mary Frances, Ball, Graham R.

“…Acute myeloid leukemia (AML) is a heterogeneous group of hematological malignancies with individual cases showing wide variations in response to treatment…”
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Rare apolipoprotein E variant identified in a patient with type III hyperlipidaemia by Wenham, P R, McDowell, I F, Hodges, V M, McEneny, J, O'Kane, M J, Davies, R J, Nicholls, D P, Trimble, E R, Blundell, G

“…We report a rare apolipoprotein E variant in an Irish female with Type III hyperlipidaemia who has the phenotype E2E1 as determined by isoelectric focusing…”
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Expression and mutagenesis of recombinant human and murine erythropoietins in Escherichia coli by Bill, Roslyn M., Winter, Paul C., McHale, Cliona M., Hodges, Vivien M., Elder, G.Elizabeth, Caley, Jane, Flitsch, Sabine L., Bicknell, Roy, Lappin, Terence R.J.

“…Expression of the polypeptide hormone erythropoietin (EPO) in Escherichia coli by four bacterial expression vectors was examined. Complementary DNAs encoding…”
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